DNA Delivery and Genomic Integration into Mammalian Target Cells through Type IV A and B Secretion Systems of Human Pathogens

Gene therapy using bacterial vectors

(2017) Peter Celec   Frontiers in Bioscience-Landmark

Substrate translocation involves specific lysine residues of the central channel of the conjugative coupling protein TrwB

(2017) Delfina Larrea et al.   MOLECULAR GENETICS AND GENOMICS

Pathogenic Helicobacter pylori strains translocate DNA and activate TLR9 via the cancer-associated cag type IV secretion system

(2016) M G Varga et al.   ONCOGENE

Subversion of Retrograde Trafficking by Translocated Pathogen Effectors

(2016) Nicolas Personnic et al.   TRENDS IN MICROBIOLOGY

Structural Biology of Bacterial Type IV Secretion Systems

(2015) Vidya Chandran Darbari et al.   Annual Review of Biochemistry

Towards an integrated model of bacterial conjugation

(2014) Elena Cabezón et al.   FEMS MICROBIOLOGY REVIEWS

Legionella pneumophila type IV effectors hijack the transcription and translation machinery of the host cell

(2014) Monica Rolando et al.   TRENDS IN CELL BIOLOGY

A Screen of Coxiella burnetii Mutants Reveals Important Roles for Dot/Icm Effectors and Host Autophagy in Vacuole Biogenesis

(2014) Hayley J. Newton et al.   PLoS Pathogens

A Translocation Motif in Relaxase TrwC Specifically Affects Recruitment by Its Conjugative Type IV Secretion System

(2013) A. Alperi et al.   JOURNAL OF BACTERIOLOGY

Effector Protein Translocation by the Coxiella burnetii Dot/Icm Type IV Secretion System Requires Endocytic Maturation of the Pathogen-Occupied Vacuole

(2013) Hayley J. Newton et al.   PLoS One

HUH site-specific recombinases for targeted modification of the human genome

(2013) Coral González-Prieto et al.   TRENDS IN BIOTECHNOLOGY

Assembly and mechanisms of bacterial type IV secretion machines

(2012) E. L. Zechner et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Site-Specific Integration of Foreign DNA into Minimal Bacterial and Human Target Sequences Mediated by a Conjugative Relaxase

(2012) Leticia Agúndez et al.   PLoS One

New perspectives into bacterial DNA transfer to human cells

(2012) Matxalen Llosa et al.   TRENDS IN MICROBIOLOGY

Isolation from Animal Tissue and Genetic Transformation of Coxiella burnetii Are Facilitated by an Improved Axenic Growth Medium

(2011) Anders Omsland et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The Coxiella burnetii Cryptic Plasmid Is Enriched in Genes Encoding Type IV Secretion System Substrates

(2011) D. E. Voth et al.   JOURNAL OF BACTERIOLOGY

Transfer of R388 Derivatives by a Pathogenesis-Associated Type IV Secretion System into both Bacteria and Human Cells

(2011) Esther Fernández-González et al.   JOURNAL OF BACTERIOLOGY

Conjugative DNA transfer into human cells by the VirB/VirD4 type IV secretion system of the bacterial pathogen Bartonella henselae

(2011) G. Schroder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Coxiella burnetii Dot/Icm System Delivers a Unique Repertoire of Type IV Effectors into Host Cells and Is Required for Intracellular Replication

(2011) Kimberly L. Carey et al.   PLoS Pathogens

Modulation of Host Cell Function byLegionella pneumophilaType IV Effectors

(2010) Andree Hubber et al.   Annual Review of Cell and Developmental Biology

Nuclear Targeting of a Bacterial Integrase That Mediates Site-Specific Recombination between Bacterial and Human Target Sequences

(2010) Leticia Agúndez et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Functional Dissection of the Conjugative Coupling Protein TrwB

(2010) H. D. de Paz et al.   JOURNAL OF BACTERIOLOGY

Legionella pneumophila Promotes Functional Interactions between Plasma Membrane Syntaxins and Sec22b

(2010) Kohei Arasaki et al.   TRAFFIC

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS