Entamoeba histolytica EhCP112 Dislocates and Degrades Claudin-1 and Claudin-2 at Tight Junctions of the Intestinal Epithelium

Cortactin deficiency causes increased RhoA/ROCK1-dependent actomyosin contractility, intestinal epithelial barrier dysfunction, and disproportionately severe DSS-induced colitis

(2017) A F Citalán-Madrid et al.   Mucosal Immunology

Toxoplasma gondii Infection Promotes Epithelial Barrier Dysfunction of Caco-2 Cells

(2016) Marisol Pallete Briceño et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Tight junctions: from simple barriers to multifunctional molecular gates

(2016) Ceniz Zihni et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Entamoeba histolytica Cysteine Proteinase 5 Evokes Mucin Exocytosis from Colonic Goblet Cells via αvβ3 Integrin

(2016) Steve Cornick et al.   PLoS Pathogens

Transcriptional Regulators of Claudins in Epithelial Tight Junctions

(2015) Niamat Khan et al.   MEDIATORS OF INFLAMMATION

Conceptual barriers to understanding physical barriers

(2015) Amulya Lingaraju et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

EhVps32 Is a Vacuole-Associated Protein Involved in Pinocytosis and Phagocytosis of Entamoeaba histolytica

(2015) Yunuen Avalos-Padilla et al.   PLoS Pathogens

Molecular aspects of tight junction barrier function

(2014) Guo Hua Liang et al.   CURRENT OPINION IN PHARMACOLOGY

Crystal Structure of a Claudin Provides Insight into the Architecture of Tight Junctions

(2014) H. Suzuki et al.   SCIENCE

Entamoeba histolytica Exacerbates Epithelial Tight Junction Permeability and Proinflammatory Responses in Muc2−/− Mice

(2013) Vanessa Kissoon-Singh et al.   AMERICAN JOURNAL OF PATHOLOGY

Changes in the expression levels of tight junction components during reconstruction of tight junction from mucosal lesion by intestinal ischemia/reperfusion

(2013) Yusuke Takizawa et al.   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

Effect of the silencing of the Ehcp112 gene on the in vitro virulence of Entamoeba histolytica

(2013) Ramón Ocádiz-Ruiz et al.   Parasites & Vectors

Salmonella Infection Upregulates the Leaky Protein Claudin-2 in Intestinal Epithelial Cells

(2013) Yong-guo Zhang et al.   PLoS One

The EhCPADH112 Complex of Entamoeba histolytica Interacts with Tight Junction Proteins Occludin and Claudin-1 to Produce Epithelial Damage

(2013) Abigail Betanzos et al.   PLoS One

Identification of the Virulence Landscape Essential for Entamoeba histolytica Invasion of the Human Colon

(2013) Roman Thibeaux et al.   PLoS Pathogens

Good Caco-2 cell culture practices

(2012) Manuela Natoli et al.   TOXICOLOGY IN VITRO

Prostaglandin E2 Produced by Entamoeba histolytica Signals via EP4 Receptor and Alters Claudin-4 to Increase Ion Permeability of Tight Junctions

(2011) Manigandan Lejeune et al.   AMERICAN JOURNAL OF PATHOLOGY

Giardia disrupts the arrangement of tight, adherens and desmosomal junction proteins of intestinal cells

(2011) C. Maia-Brigagão et al.   PARASITOLOGY INTERNATIONAL

The immunopathogenesis of Entamoeba histolytica

(2010) Leanne Mortimer et al.   EXPERIMENTAL PARASITOLOGY

Entamoeba histolyticaCysteine Proteinase 5 Binds Integrin on Colonic Cells and Stimulates NFκB-mediated Pro-inflammatory Responses

(2010) Yongzhong Hou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Major cysteine peptidases ofEntamoeba histolyticaare required for aggregation and digestion of erythrocytes but are dispensable for phagocytosis and cytopathogenicity

(2009) Henriette Irmer et al.   MOLECULAR MICROBIOLOGY

Purification, refolding and autoactivation of the recombinant cysteine proteinase EhCP112 from Entamoeba histolytica

(2008) Laura I. Quintas-Granados et al.   PROTEIN EXPRESSION AND PURIFICATION