With Friends Like These: The Complex Role of Neutrophils in the Progression of Severe Pneumonia

Capsules of virulent pneumococcal serotypes enhance formation of neutrophil extracellular traps during in vivo pathogenesis of pneumonia

(2016) Anandi Narayana Moorthy et al.   Oncotarget

Relevant Cytokines in the Management of Community-Acquired Pneumonia

(2016) Adrian Rendon et al.   Current Infectious Disease Reports

Neutrophil Extracellular Traps in Pulmonary Diseases: Too Much of a Good Thing?

(2016) Bárbara Nery Porto et al.   Frontiers in Immunology

S. aureus blocks efferocytosis of neutrophils by macrophages through the activity of its virulence factor alpha toxin

(2016) Taylor S. Cohen et al.   Scientific Reports

Dynamics of Lung Defense in Pneumonia: Resistance, Resilience, and Remodeling

(2015) Lee J. Quinton et al.   Annual Review of Physiology

In Vivo Transcriptional Profiling of Yersinia pestis Reveals a Novel Bacterial Mediator of Pulmonary Inflammation

(2015) Roger D. Pechous et al.   mBio

Spatially Distinct Neutrophil Responses within the Inflammatory Lesions of Pneumonic Plague

(2015) Nikolas M. Stasulli et al.   mBio

Extracellular Adenosine Protects against Streptococcus pneumoniae Lung Infection by Regulating Pulmonary Neutrophil Recruitment

(2015) Elsa N. Bou Ghanem et al.   PLoS Pathogens

Lipid Mediators in the Resolution of Inflammation

(2014) Charles N. Serhan et al.   Cold Spring Harbor Perspectives in Biology

Neutrophil Elastase Causes Tissue Damage That Decreases Host Tolerance to Lung Infection with Burkholderia Species

(2014) Manoranjan Sahoo et al.   PLoS Pathogens

A Systems Analysis Identifies a Feedforward Inflammatory Circuit Leading to Lethal Influenza Infection

(2013) Marlène Brandes et al.   CELL

Systemic Disease during Streptococcus pneumoniae Acute Lung Infection Requires 12-Lipoxygenase-Dependent Inflammation

(2013) R. Bhowmick et al.   JOURNAL OF IMMUNOLOGY

Early Host Cell Targets of Yersinia pestis during Primary Pneumonic Plague

(2013) Roger D. Pechous et al.   PLoS Pathogens

Respiratory Infection and the Impact of Pulmonary Immunity on Lung Health and Disease

(2012) Joseph P. Mizgerd   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

CXCL10-CXCR3 Enhances the Development of Neutrophil-mediated Fulminant Lung Injury of Viral and Nonviral Origin

(2012) Akihiko Ichikawa et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Understanding the roles of cytokines and neutrophil activity and neutrophil apoptosis in the protective versus deleterious inflammatory response in pneumonia

(2012) Jose Bordon et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Infection regulates pro-resolving mediators that lower antibiotic requirements

(2012) Nan Chiang et al.   NATURE

Neutrophil Extracellular Traps Directly Induce Epithelial and Endothelial Cell Death: A Predominant Role of Histones

(2012) Mona Saffarzadeh et al.   PLoS One

Excessive Neutrophils and Neutrophil Extracellular Traps Contribute to Acute Lung Injury of Influenza Pneumonitis

(2011) Teluguakula Narasaraju et al.   AMERICAN JOURNAL OF PATHOLOGY

Cathepsin G and Neutrophil Elastase Play Critical and Nonredundant Roles in Lung-Protective Immunity against Streptococcus pneumoniae in Mice

(2011) Ines Hahn et al.   INFECTION AND IMMUNITY

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(2011) Jochen Grommes et al.   MOLECULAR MEDICINE

Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils

(2011) Stephen J Galli et al.   NATURE IMMUNOLOGY

In vivo efficacy of KRP-109, a novel elastase inhibitor, in a murine model of severe pneumococcal pneumonia

(2011) Koichi Yamada et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Neutrophil α-Defensins Cause Lung Injury by Disrupting the Capillary–Epithelial Barrier

(2010) Khalil Bdeir et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Nonresolving Inflammation

(2010) Carl Nathan et al.   CELL

CXCL5 Regulates Chemokine Scavenging and Pulmonary Host Defense to Bacterial Infection

(2010) Junjie Mei et al.   IMMUNITY

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

Neutrophil Elastase, Proteinase 3, and Cathepsin G as Therapeutic Targets in Human Diseases

(2010) B. Korkmaz et al.   PHARMACOLOGICAL REVIEWS

In vivo two-photon imaging reveals monocyte-dependent neutrophil extravasation during pulmonary inflammation

(2010) D. Kreisel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Leukocyte Elastase Induces Lung Epithelial Apoptosis via a PAR-1–, NF-κB–, and p53-Dependent Pathway

(2009) Tomoko Suzuki et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Severe Community-Acquired Pneumonia

(2009) Marcos I. Restrepo et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Dying and Necrotic Neutrophils Are Anti-Inflammatory Secondary to the Release of  -Defensins

(2009) K. Miles et al.   JOURNAL OF IMMUNOLOGY

Human Neutrophils Kill Streptococcus pneumoniae via Serine Proteases

(2009) A. J. Standish et al.   JOURNAL OF IMMUNOLOGY

Human defensins and LL-37 in mucosal immunity

(2009) Mona Doss et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Polymorphonuclear neutrophils and T lymphocytes: strange bedfellows or brothers in arms?

(2009) Ingrid Müller et al.   TRENDS IN IMMUNOLOGY

Neutrophil degranulation mediates severe lung damage triggered by streptococcal M1 protein

(2008) O. Soehnlein et al.   EUROPEAN RESPIRATORY JOURNAL

The role of the multifunctional peptide LL-37 in host defense

(2008) Ylva Kai-Larsen   Frontiers in Bioscience-Landmark

Neutrophil Recruitment to the Lungs during Bacterial Pneumonia

(2008) A. Craig et al.   INFECTION AND IMMUNITY

Acute Lower Respiratory Tract Infection

(2008) Joseph P. Mizgerd   NEW ENGLAND JOURNAL OF MEDICINE