Article
Horticulture
Hyun Ju Ju, Kyeoung Cheol Kim, Heekyu Kim, Ju-Sung Kim, Tae Kyung Hyun
Summary: The study revealed significant impacts of genotype on phytonutrients and biological activities of Perilla frutescens var. crispa (Pfc). Different genotypes showed variations in phytochemical composition and biological effects, with Pfc 5 exhibiting antimelanogenic activity and Pfc 2 showing strong anti-inflammatory effects. These findings are important for the breeding and genetic engineering of Pfc to address future phytonutrition and health challenges.
Article
Food Science & Technology
Keiya Shimamori, Tomohiko Nambu, Daiki Kawamata, Masahiro Kuragano, Naoki Nishishita, Toshifumi Iimori, Shinya Yamanaka, Koji Uwai, Kiyotaka Tokuraku
Summary: This study found that the cultivation environment affects the inhibitory activity of Perilla frutescens var. crispa on Aβ aggregation, with the highest activity observed in plants harvested just before flowering. Wind-shielded plants had reduced activity compared to plants just before flowering. Additionally, appropriate nitrogen fertilization and at least one week of drying increased the activity of Perilla frutescens var. crispa. Furthermore, leaf extracts of Perilla frutescens var. crispa suppressed Aβ-induced toxicity in nerve growth factor-differentiated PC12 cells. This study provides practical cultivation methods for Perilla frutescens var. crispa with high Aβ aggregation inhibitory activity for the prevention of AD.
Review
Food Science & Technology
Shu Taira, Aya Kiriake-Yoshinaga, Hitomi Shikano, Ryuzoh Ikeda, Shoko Kobayashi, Kazuaki Yoshinaga
Summary: The study successfully localized essential oils such as perillaldehyde, beta-caryophyllene, and rosmarinic acid in perilla herb using MALDI mass spectrometry imaging, providing a new method for the quantification of essential oils.
FOOD SCIENCE & NUTRITION
(2021)
Article
Pharmacology & Pharmacy
NamHoon Kim, Si-Yeon Kim, Sang-Woo Kim, Jung Min Lee, Sung-Kyu Kim, Mi-Houn Park, Ki-Hwan Kim, Minseok Oh, Chang-Gue Son, In Chul Jung, Eun-Jung Lee
Summary: This study aimed to evaluate the clinical efficacy and safety of PE extracts on semi-healthy people with mild knee joint pain. The results showed that PE intake for eight weeks was more effective than placebo in reducing knee joint pain and improving knee joint function. It was concluded that PE extracts were effective and safe for relieving knee joint pain and improving knee joint function.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Food Science & Technology
Jisu Lee, Youngjae Shin
Summary: This study found that 'Antisperill' contains various antioxidants, and microwave-assisted low temperature vacuum drying is the optimal method to preserve and enhance its antioxidant content.
FOOD SCIENCE AND BIOTECHNOLOGY
(2023)
Article
Agronomy
Thi Kim Loan Nguyen, Moon-Sun Yeom, Myung-Min Oh
Summary: The study found that red perilla showed different growth characteristics and compound contents at different electrical conductivity levels, with NSP 1 dS m(-1) performing the best.
Article
Agricultural Engineering
SuYun Ding, ZhiQian Yan, HuiPing Liu, Pei Chen, ShuYuan Shi, MengLi Chang
Summary: The polysaccharide PFP extracted from Perilla frutescens var. frutescens has antitumor activity by inhibiting tumor proliferation through blocking the cell cycle S phase, and also exhibits protective effects on mouse liver and thymus tissues.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Biochemistry & Molecular Biology
Wen-Fang Tang, Hui-Ping Tsai, Yu-Hsiu Chang, Tein-Yao Chang, Chung-Fan Hsieh, Chia-Yi Lin, Guan-Hua Lin, Yu-Li Chen, Jia-Rong Jheng, Ping-Cheng Liu, Chuen-Mi Yang, Yuan-Fan Chin, Cheng Cheung Chen, Jyh-Hwa Kau, Yi-Jen Hung, Po-Shiuan Hsieh, Jim-Tong Horng
Summary: The study found that Perilla leaf extract could inhibit SARS-CoV-2 replication by inactivating the virus, blocking viral infection steps, reducing viral replication and inflammation response. Moreover, it showed additive-to-synergistic efficacy when used in combination with remdesivir.
BIOMEDICAL JOURNAL
(2021)
Article
Agriculture, Multidisciplinary
Xiaoxiang Han, Jianghui Huang, Jinwang Cai, Chen Yu, Shengchou Jiang, Qing Ye, Shuifen Yang, Weichun Pan, Qiaozhi Zhang, Yanbo Wang
Summary: In this study, anthocyanins were successfully extracted from purple perilla leaves using natural deep eutectic solvents (DESs) and microwave-ultrasonic assisted extraction (MUAE). The extraction method was efficient, energy-saving, and environmentally friendly. The biological activity and bacteriostatic impact of the extract were evaluated.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Virology
Yu-Ting Kuo, Ching-Hsuan Liu, Angela Corona, Elisa Fanunza, Enzo Tramontano, Liang-Tzung Lin
Summary: Ebola virus is a highly infectious and deadly virus, and PFME has been identified as an effective inhibitor of EBOV entry, blocking viral spread and infection.
Review
Biochemistry & Molecular Biology
Gigi Adam, Silvia Robu, Mihaela-Magdalena Flutur, Oana Cioanca, Ingrid-Andrada Vasilache, Ana-Maria Adam, Cornelia Mircea, Aurel Nechita, Valeriu Harabor, AnaMaria Harabor, Monica Hancianu
Summary: This review aims to provide an updated understanding of the clinical applications of Perilla frutescens through human studies and outline potential directions for further research. The findings suggest significant clinical effects of Perilla frutescens extracts on allergic rhinoconjuctivitis, especially in young populations, as well as a potent hypolipemiant effect and potential improvements in cognitive function. Supplementary research in controlled clinical settings is needed to confirm these therapeutic effects.
Article
Food Science & Technology
Eunbi Cho, Jihye Lee, Jae Seong Sin, Sung-kyu Kim, Chul Jin Kim, Mi Hee Park, Wan-Seob Cho, Minho Moon, Dong Hyun Kim, Ji Wook Jung
Summary: This study investigated the effects of a standardized ethanol extract of Perilla frutescens var. acuta (L.) Britt. (Lamiaceae) on various pathologies of Alzheimer's Disease (AD) in 5XFAD mice. The extract was found to block A beta aggregation, disassemble pre-formed A beta aggregates, and ameliorate memory impairments. Additionally, it reduced A beta deposits and neuroinflammation in the hippocampus of the mice. These findings suggest that the extract could be a promising therapeutic candidate for AD.
FOOD AND CHEMICAL TOXICOLOGY
(2022)
Article
Multidisciplinary Sciences
Renyan Liao
Summary: The present study explored the effects of different concentrations of abscisic acid (ABA) on the growth and selenium (Se) absorption capacity of Perilla frutescens. The results showed that 5 and 10 μmol/L ABA promoted the growth of P. frutescens and enhanced the Se accumulation capacity, while 5 μmol/L ABA increased the Se content, Se extraction, and Se bioconcentration factor.
Article
Nanoscience & Nanotechnology
N. Reddy, Huizhen Li, Tianyu Hou, M. S. Bethu, Zhiqing Ren, Zhijun Zhang
Summary: This study successfully synthesized PF@AgNPs using Perilla frutescens leaf extract, which possess antibacterial, antioxidant, and anticancer activities. PF@AgNPs showed good physical properties and significant inhibition activities against various cancer cell lines.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2021)
Article
Agricultural Engineering
Jin Hwan Lee, Yong-Sung Cho
Summary: The research aimed to compare phenolic contents and beneficial effects from different organs of Korean perilla species, showing significant variations in antioxidant and enzyme inhibitory activities. Perilla seeds, especially from P. frutescens and P. citriodora, exhibited predominant abilities, making them potential sources for natural nutraceutical uses.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Article
Entomology
William R. Morrison, Chang-Gyu Park, Bo Yoon Seo, Yong-Lak Park, Hong Geun Kim, Kevin B. Rice, Doo-Hyung Lee, Tracy C. Leskey
JOURNAL OF PEST SCIENCE
(2017)
Article
Entomology
Seung-Phil Chun, Young-Chul Jun, Hong-Geun Kim, Woo-Kyun Lee, Myoung-Chul Kim, Seung-Hoon Chun, Sung-Eun Jung
JOURNAL OF ASIA-PACIFIC ENTOMOLOGY
(2017)
Article
Entomology
Sun Young Kim, Hong Geun Kim, Hyung Joo Yoon, Kyeong Yong Lee, Nam Jung Kim
ENTOMOLOGICAL RESEARCH
(2017)
Article
Entomology
Seung-Phil Chun, Young-Chul Jun, Hong-Geun Kim, Woo-Kyun Lee, Myoung-Chul Kim, Seung-Hoon Chun, Sung-Eun Jung
JOURNAL OF ASIA-PACIFIC ENTOMOLOGY
(2017)
Editorial Material
Entomology
Hong Geun Kim, Jong-Seok Park, Doo-Hyung Lee
FLORIDA ENTOMOLOGIST
(2018)
Correction
Entomology
Seung-Phil Chun, Young-Chul Jung, Hong-Geun Kim, Woo-Kyun Lee, Myoung-Chul Kim, Seung-Hoon Chun, Sung-Eun Jung
JOURNAL OF ASIA-PACIFIC ENTOMOLOGY
(2018)
Article
Entomology
Minhyung Jung, Soowan Kim, Hong Geun Kim, Doo-Hyung Lee
JOURNAL OF ASIA-PACIFIC ENTOMOLOGY
(2018)
Article
Entomology
Hong Geun Kim, David C. Margolies, Yoonseong Park
PHYSIOLOGICAL ENTOMOLOGY
(2018)
Correction
Entomology
Seung-Phil Chun, Young-Chul Jung, Hong-Geun Kim, Woo-Kyun Lee, Myoung-Chul Kim, Seung-Hoon Chun, Sung-Eun Jung
JOURNAL OF ASIA-PACIFIC ENTOMOLOGY
(2018)
Article
Entomology
Minhyung Jung, Soowan Kim, Hong Geun Kim, Doo-Hyung Lee
JOURNAL OF ASIA-PACIFIC ENTOMOLOGY
(2018)
Review
Biotechnology & Applied Microbiology
Hong Geun Kim, Doo-Hyung Lee
BIOCONTROL SCIENCE AND TECHNOLOGY
(2019)
Article
Entomology
Kisang Kwon, Ji-Hye Song, Honggeun Kim, O-Yu Kwon
JOURNAL OF THE KANSAS ENTOMOLOGICAL SOCIETY
(2020)
Article
Entomology
Hong Geun Kim, Minhyung Jung, Doo-Hyung Lee
Summary: Seasonal activity and SFTS virus carriership of ticks in a rural area of South Korea were studied. The dominant tick species was Haemaphysalis longicornis, with larvae mostly found in grave areas and nymphs and adults in grasslands. Only one SFTS virus-positive sample was detected in 2019, while 18 positive samples were found from August to October in 2020.
EXPERIMENTAL AND APPLIED ACAROLOGY
(2022)
Article
Entomology
Ji-Hye Song, Kisang Kwon, Nuri Lee, Hyojung Shin, Dong Woon Kim, Honggeun Kim, O-Yu Kwon
JOURNAL OF THE KANSAS ENTOMOLOGICAL SOCIETY
(2019)