Direct measurement of conformational strain energy in protofilaments curling outward from disassembling microtubule tips

Microtubules self-repair in response to mechanical stress

(2015) Laura Schaedel et al.   NATURE MATERIALS

A mutation uncouples the tubulin conformational and GTPase cycles, revealing allosteric control of microtubule dynamics

(2015) Elisabeth A Geyer et al.   eLife

Tubulin Bond Energies and Microtubule Biomechanics Determined from Nanoindentation in Silico

(2014) Olga Kononova et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A tethered delivery mechanism explains the catalytic action of a microtubule polymerase

(2014) Pelin Ayaz et al.   eLife

Conserved and divergent features of kinetochores and spindle microtubule ends from five species

(2013) J. Richard McIntosh et al.   JOURNAL OF CELL BIOLOGY

Long tethers provide high-force coupling of the Dam1 ring to shortening microtubules

(2013) V. A. Volkov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cortical Dynein Controls Microtubule Dynamics to Generate Pulling Forces that Position Microtubule Asters

(2012) Liedewij Laan et al.   CELL

A TOG:  -tubulin Complex Structure Reveals Conformation-Based Mechanisms for a Microtubule Polymerase

(2012) P. Ayaz et al.   SCIENCE

Design, Overexpression, and Purification of Polymerization-Blocked Yeast αβ-Tubulin Mutants

(2011) Vinu Johnson et al.   BIOCHEMISTRY

Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B

(2010) Jerry F. Tien et al.   JOURNAL OF CELL BIOLOGY

Tubulin depolymerization may be an ancient biological motor

(2010) J. R. McIntosh et al.   JOURNAL OF CELL SCIENCE

Direct physical study of kinetochore–microtubule interactions by reconstitution and interrogation with an optical force clamp

(2010) Andrew D. Franck et al.   METHODS

Tension directly stabilizes reconstituted kinetochore-microtubule attachments

(2010) Bungo Akiyoshi et al.   NATURE

Kinetochores’ gripping feat: conformational wave or biased diffusion?

(2010) Charles L. Asbury et al.   TRENDS IN CELL BIOLOGY

The Ndc80 Kinetochore Complex Forms Load-Bearing Attachments to Dynamic Microtubule Tips via Biased Diffusion

(2009) Andrew F. Powers et al.   CELL

EB1 Recognizes the Nucleotide State of Tubulin in the Microtubule Lattice

(2009) Marija Zanic et al.   PLoS One

Fibrils Connect Microtubule Tips with Kinetochores: A Mechanism to Couple Tubulin Dynamics to Chromosome Motion

(2008) J. Richard McIntosh et al.   CELL