Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma

The evolution of the unstable cancer genome

(2014) Rebecca A Burrell et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Tumour heterogeneity and the evolution of polyclonal drug resistance

(2014) Rebecca A. Burrell et al.   Molecular Oncology

Clonal evolution in breast cancer revealed by single nucleus genome sequencing

(2014) Yong Wang et al.   NATURE

Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer

(2014) Jens G Lohr et al.   NATURE BIOTECHNOLOGY

Chromosome instability induced by Mps1 and p53 mutation generates aggressive lymphomas exhibiting aneuploidy-induced stress

(2014) Floris Foijer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

(2014) E. C. de Bruin et al.   SCIENCE

Cumulative Haploinsufficiency and Triplosensitivity Drive Aneuploidy Patterns and Shape the Cancer Genome

(2013) Teresa Davoli et al.   CELL

Pan-cancer patterns of somatic copy number alteration

(2013) Travis I Zack et al.   NATURE GENETICS

Spindle checkpoint deficiency is tolerated by murine epidermal cells but not hair follicle stem cells

(2013) F. Foijer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer Karyotypes: Survival of the Fittest

(2013) Joshua M. Nicholson et al.   Frontiers in Oncology

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification of Aneuploidy-Tolerating Mutations

(2010) Eduardo M. Torres et al.   CELL

Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemia

(2010) Letetia Jones et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal

(2010) Rocio Sotillo et al.   NATURE

The ploidy conveyor of mature hepatocytes as a source of genetic variation

(2010) Andrew W. Duncan et al.   NATURE

Whole Chromosome Instability Caused by Bub1 Insufficiency Drives Tumorigenesis through Tumor Suppressor Gene Loss of Heterozygosity

(2009) Darren J. Baker et al.   CANCER CELL

Cre activity in fetalalbCremouse hepatocytes: Utility for developmental studies

(2009) Carla M. Weisend et al.   GENESIS

Loss of spindle assembly checkpoint–mediated inhibition of Cdc20 promotes tumorigenesis in mice

(2009) Min Li et al.   JOURNAL OF CELL BIOLOGY

The R246S hot-spot p53 mutant exerts dominant-negative effects in embryonic stem cells in vitro and in vivo

(2008) M. K. Lee et al.   JOURNAL OF CELL SCIENCE

Genomic stability and tumour suppression by the APC/C cofactor Cdh1

(2008) Irene García-Higuera et al.   NATURE CELL BIOLOGY

Losses of Chromosome Arms 4q, 8p, 13q and Gain of 8q Are Correlated with Increasing Chromosomal Instability in Hepatocellular Carcinoma

(2008) Sabine Hertz et al.   PATHOBIOLOGY

Aneuploidy Affects Proliferation and Spontaneous Immortalization in Mammalian Cells

(2008) B. R. Williams et al.   SCIENCE

Mouse models in liver cancer research: A review of current literature

(2008) Martijn WH Leenders et al.   WORLD JOURNAL OF GASTROENTEROLOGY