Structure of Fam20A reveals a pseudokinase featuring a unique disulfide pattern and inverted ATP-binding

Periodontal disease and FAM20A mutations

(2017) Piranit Nik Kantaputra et al.   JOURNAL OF HUMAN GENETICS

Non lethal Raine syndrome and differential diagnosis

(2016) Siham Chafai Elalaoui et al.   European Journal of Medical Genetics

Raine Syndrome (OMIM #259775), Caused By FAM20C Mutation, Is Congenital Sclerosing Osteomalacia With Cerebral Calcification (OMIM 259660)

(2016) Michael P Whyte et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Structural Basis for the Non-catalytic Functions of Protein Kinases

(2016) Jennifer E. Kung et al.   STRUCTURE

Structure of protein O-mannose kinase reveals a unique active site architecture

(2016) Qinyu Zhu et al.   eLife

Novel FAM20A mutation causes autosomal recessive amelogenesis imperfecta

(2015) Michael Volodarsky et al.   ARCHIVES OF ORAL BIOLOGY

The secretory pathway kinases

(2015) Anju Sreelatha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Variability of systemic and oro-dental phenotype in two families with non-lethal Raine syndrome with FAM20C mutations

(2015) Ana Carolina Acevedo et al.   BMC Medical Genetics

A Single Kinase Generates the Majority of the Secreted Phosphoproteome

(2015) Vincent S. Tagliabracci et al.   CELL

Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2)

(2015) Xiaoshan Min et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

Further evidence for causal FAM20A mutations and first case of amelogenesis imperfecta and gingival hyperplasia syndrome in Morocco: a case report

(2015) Imane Cherkaoui Jaouad et al.   BMC Oral Health

A secretory kinase complex regulates extracellular protein phosphorylation

(2015) Jixin Cui et al.   eLife

Enamel-Renal-Gingival syndrome, hypodontia, and a novelFAM20Amutation

(2014) Piranit Nik Kantaputra et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Hypophosphatemic osteomalacia and bone sclerosis caused by a novel homozygous mutation of the FAM20C gene in an elderly man with a mild variant of Raine syndrome

(2014) Shinji Takeyari et al.   BONE

RETRACTED: An ATP-Competitive Inhibitor Modulates the Allosteric Function of the HER3 Pseudokinase

(2014) Peter Littlefield et al.   CHEMISTRY & BIOLOGY

Kinases and Pseudokinases: Lessons from RAF

(2014) A. S. Shaw et al.   MOLECULAR AND CELLULAR BIOLOGY

Dimeric Structure of Pseudokinase RNase L Bound to 2-5A Reveals a Basis for Interferon-Induced Antiviral Activity

(2014) Hao Huang et al.   MOLECULAR CELL

Interplay of Mg2+, ADP, and ATP in the cytosol and mitochondria: Unravelling the role of Mg2+ in cell respiration

(2014) E. Gout et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Xylose phosphorylation functions as a molecular switch to regulate proteoglycan biosynthesis

(2014) J. Wen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN Response

(2014) Y. Han et al.   SCIENCE

Enamel-renal-gingival syndrome andFAM20Amutations

(2013) Piranit Nik Kantaputra et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL

(2013) James M. Murphy et al.   BIOCHEMICAL JOURNAL

A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties

(2013) James M. Murphy et al.   BIOCHEMICAL JOURNAL

Phosphorylation of substrates destined for secretion by the Fam20 kinases

(2013) Vincent S. Tagliabracci et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

(2013) James M. Murphy et al.   IMMUNITY

Exome sequencing reveals FAM20c mutations associated with fibroblast growth factor 23-related hypophosphatemia, dental anomalies, and ectopic calcification

(2013) Silje Hjorth Rafaelsen et al.   JOURNAL OF BONE AND MINERAL RESEARCH

FAM20A Mutations Associated with Enamel Renal Syndrome

(2013) S.K. Wang et al.   JOURNAL OF DENTAL RESEARCH

Autosomal recessive gingival hyperplasia and dental anomalies caused by a 29-base pair duplication in the FAM20A gene

(2013) Rita M Cabral et al.   JOURNAL OF HUMAN GENETICS

Nephrocalcinosis (Enamel Renal Syndrome) Caused by Autosomal RecessiveFAM20AMutations

(2013) Graciana Jaureguiberry et al.   NEPHRON PHYSIOLOGY

Crystal structure of the Golgi casein kinase

(2013) J. Xiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FAM20A Mutations Can Cause Enamel-Renal Syndrome (ERS)

(2013) Shih-Kai Wang et al.   PLoS Genetics

Crystal structures of the JAK2 pseudokinase domain and the pathogenic mutant V617F

(2012) Rajintha M Bandaranayake et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Secreted Kinase Phosphorylates Extracellular Proteins That Regulate Biomineralization

(2012) V. S. Tagliabracci et al.   SCIENCE

Secreted protein kinases

(2012) Vincent S. Tagliabracci et al.   TRENDS IN BIOCHEMICAL SCIENCES

Whole-Exome Sequencing Identifies FAM20A Mutations as a Cause of Amelogenesis Imperfecta and Gingival Hyperplasia Syndrome

(2011) James O'Sullivan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Novel FAM20A mutations in hypoplastic amelogenesis imperfecta

(2011) Sang Hyun Cho et al.   HUMAN MUTATION

LigPlot+: Multiple Ligand–Protein Interaction Diagrams for Drug Discovery

(2011) Roman A. Laskowski et al.   Journal of Chemical Information and Modeling

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Osteosclerotic bone dysplasia in siblings with a Fam20C mutation

(2010) M Fradin et al.   CLINICAL GENETICS

Pseudokinases-remnants of evolution or key allosteric regulators?

(2010) Elton Zeqiraj et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Dali server: conservation mapping in 3D

(2010) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation

(2010) Fumin Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FAM20B is a kinase that phosphorylates xylose in the glycosaminoglycan–protein linkage region

(2009) Toshiyasu Koike et al.   BIOCHEMICAL JOURNAL

Appion: An integrated, database-driven pipeline to facilitate EM image processing

(2009) Gabriel C. Lander et al.   JOURNAL OF STRUCTURAL BIOLOGY

DoG Picker and TiltPicker: Software tools to facilitate particle selection in single particle electron microscopy

(2009) N.R. Voss et al.   JOURNAL OF STRUCTURAL BIOLOGY

The Pseudoactive Site of ILK Is Essential for Its Binding to α-Parvin and Localization to Focal Adhesions

(2009) Koichi Fukuda et al.   MOLECULAR CELL

Crystal structure of the catalytic domain of Haspin, an atypical kinase implicated in chromatin organization

(2009) F. Villa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and functional characterization of the atypical human kinase haspin

(2009) J. Eswaran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural analysis of the catalytically inactive kinase domain of the human EGF receptor 3

(2009) N. Jura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP and MO25α Regulate the Conformational State of the STRADα Pseudokinase and Activation of the LKB1 Tumour Suppressor

(2009) Elton Zeqiraj et al.   PLOS BIOLOGY

CASK Functions as a Mg2+-Independent Neurexin Kinase

(2008) Konark Mukherjee et al.   CELL

PROMALS3D: a tool for multiple protein sequence and structure alignments

(2008) Jimin Pei et al.   NUCLEIC ACIDS RESEARCH