Anti-diabetic drug binding site in a mammalian KATP channel revealed by Cryo-EM
Published 2017 View Full Article
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Title
Anti-diabetic drug binding site in a mammalian KATP channel revealed by Cryo-EM
Authors
Keywords
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Journal
eLife
Volume 6, Issue -, Pages -
Publisher
eLife Sciences Organisation, Ltd.
Online
2017-10-16
DOI
10.7554/elife.31054
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Note: Only part of the references are listed.- MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
- (2017) Shawn Q Zheng et al. NATURE METHODS
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- (2015) Prasanna K. Devaraneni et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2008) Yu-Wen Lin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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