Loss of the melanocortin-4 receptor in mice causes dilated cardiomyopathy

Mechanisms of Lipid Accumulation in the Bone Morphogenetic Protein Receptor Type 2 Mutant Right Ventricle

(2016) Megha H. Talati et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Inhibiting Insulin-Mediated β 2 -Adrenergic Receptor Activation Prevents Diabetes-Associated Cardiac DysfunctionClinical Perspective

(2016) Qingtong Wang et al.   CIRCULATION

The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update

(2016) Enis Afgan et al.   NUCLEIC ACIDS RESEARCH

Divergent effects of central melanocortin signalling on fat and sucrose preference in humans

(2016) Agatha A. van der Klaauw et al.   Nature Communications

An Overview of Murine High Fat Diet as a Model for Type 2 Diabetes Mellitus

(2016) Ahlke Heydemann   Journal of Diabetes Research

Molecular mechanisms of diabetic cardiomyopathy

(2014) Heiko Bugger et al.   DIABETOLOGIA

Prevalence of Childhood and Adult Obesity in the United States, 2011-2012

(2014) Cynthia L. Ogden et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Regulation and therapeutic strategies of 4-hydroxy-2-nonenal metabolism in heart disease

(2013) V. R. Mali et al.   FREE RADICAL RESEARCH

Mice Long-Term High-Fat Diet Feeding Recapitulates Human Cardiovascular Alterations: An Animal Model to Study the Early Phases of Diabetic Cardiomyopathy

(2013) Sebastián D. Calligaris et al.   PLoS One

High Fat Feeding in Mice Is Insufficient to Induce Cardiac Dysfunction and Does Not Exacerbate Heart Failure

(2013) Robert E. Brainard et al.   PLoS One

Metabolic stress–induced activation of FoxO1 triggers diabetic cardiomyopathy in mice

(2012) Pavan K. Battiprolu et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondria in cardiac hypertrophy and heart failure

(2012) Mariana G. Rosca et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Sympathetic Function in Human Carriers of Melanocortin-4 Receptor Gene Mutations

(2010) Friedhelm Sayk et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Obesity due to Melanocortin 4 Receptor (MC4R) Deficiency Is Associated with Increased Linear Growth and Final Height, Fasting Hyperinsulinemia, and Incompletely Suppressed Growth Hormone Secretion

(2010) Carlos E. Martinelli et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Adiposity and Incidence of Heart Failure Hospitalization and Mortality

(2009) Emily B. Levitan et al.   Circulation-Heart Failure

Cardiovascular effects of leptin

(2009) Gary Sweeney   Nature Reviews Cardiology

A short duration of high-fat diet induces insulin resistance and predisposes to adverse left ventricular remodeling after pressure overload

(2008) Michael J. Raher et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Prevalence of Melanocortin-4 Receptor Deficiency in Europeans and Their Age-Dependent Penetrance in Multigenerational Pedigrees

(2008) F. Stutzmann et al.   DIABETES

Endogenous Melanocortin System Activity Contributes to the Elevated Arterial Pressure in Spontaneously Hypertensive Rats

(2008) Alexandre A. da Silva et al.   HYPERTENSION

Modulation of Blood Pressure by Central Melanocortinergic Pathways

(2008) Jerry R. Greenfield et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Heterozygous Mutation in the Third Transmembrane Domain Causes a Dominant-Negative Effect on Signalling Capability of the MC4R

(2008) Patrick Tarnow et al.   Obesity Facts