Mutational phospho-mimicry reveals a regulatory role for the XRCC4 and XLF C-terminal tails in modulating DNA bridging during classical non-homologous end joining
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Mutational phospho-mimicry reveals a regulatory role for the XRCC4 and XLF C-terminal tails in modulating DNA bridging during classical non-homologous end joining
Authors
Keywords
-
Journal
eLife
Volume 6, Issue -, Pages -
Publisher
eLife Sciences Organisation, Ltd.
Online
2017-05-13
DOI
10.7554/elife.22900
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Restoration of ATM Expression in DNA-PKcs–Deficient Cells Inhibits Signal End Joining
- (2016) Jessica A. Neal et al. JOURNAL OF IMMUNOLOGY
- VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break Repair
- (2016) Johannes van den Boom et al. MOLECULAR CELL
- Sliding sleeves of XRCC4–XLF bridge DNA and connect fragments of broken DNA
- (2016) Ineke Brouwer et al. NATURE
- Bridging of double-stranded breaks by the nonhomologous end-joining ligation complex is modulated by DNA end chemistry
- (2016) Dylan A. Reid et al. NUCLEIC ACIDS RESEARCH
- Versatility in phospho-dependent molecular recognition of the XRCC1 and XRCC4 DNA-damage scaffolds by aprataxin-family FHA domains
- (2015) Amy L. Cherry et al. DNA REPAIR
- XRCC4/XLF Interaction Is Variably Required for DNA Repair and Is Not Required for Ligase IV Stimulation
- (2015) Sunetra Roy et al. MOLECULAR AND CELLULAR BIOLOGY
- Akt-Mediated Phosphorylation of XLF Impairs Non-Homologous End-Joining DNA Repair
- (2015) Pengda Liu et al. MOLECULAR CELL
- Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair
- (2015) Dylan A. Reid et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neddylation Promotes Ubiquitylation and Release of Ku from DNA-Damage Sites
- (2015) Jessica S. Brown et al. Cell Reports
- Reprint of “The clinical impact of deficiency in DNA non-homologous end-joining”
- (2014) Lisa Woodbine et al. DNA REPAIR
- A role for XLF in DNA repair and recombination in human somatic cells
- (2014) Farjana Jahan Fattah et al. DNA REPAIR
- Unraveling the Complexities of DNA-Dependent Protein Kinase Autophosphorylation
- (2014) J. A. Neal et al. MOLECULAR AND CELLULAR BIOLOGY
- Modernizing the Nonhomologous End-Joining Repertoire: Alternative and Classical NHEJ Share the Stage
- (2013) Ludovic Deriano et al. Annual Review of Genetics
- A noncatalytic function of the ligation complex during nonhomologous end joining
- (2013) Jessica Cottarel et al. JOURNAL OF CELL BIOLOGY
- RNA-Guided Human Genome Engineering via Cas9
- (2013) P. Mali et al. SCIENCE
- Non-homologous end-joining partners in a helical dance: structural studies of XLF–XRCC4 interactions
- (2012) Qian Wu et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- XRCC4's interaction with XLF is required for coding (but not signal) end joining
- (2012) S. Roy et al. NUCLEIC ACIDS RESEARCH
- A human XRCC4–XLF complex bridges DNA
- (2012) Sara N. Andres et al. NUCLEIC ACIDS RESEARCH
- Crystal Structure of a Complex of DNA with One AT-Hook of HMGA1
- (2012) Elsa Fonfría-Subirós et al. PLoS One
- Destroying the ring: Freeing DNA from Ku with ubiquitin
- (2011) Lisa Postow FEBS LETTERS
- XRCC4 Protein Interactions with XRCC4-like Factor (XLF) Create an Extended Grooved Scaffold for DNA Ligation and Double Strand Break Repair
- (2011) Michal Hammel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining
- (2011) V. Ropars et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
- (2010) Michael R. Lieber Annual Review of Biochemistry
- Dual Modes of Interaction between XRCC4 and Polynucleotide Kinase/Phosphatase
- (2010) Rajam S. Mani et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Delineation of the Xrcc4-interacting Region in the Globular Head Domain of Cernunnos/XLF
- (2010) Laurent Malivert et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks
- (2008) Y YU et al. DNA REPAIR
- APLF (C2orf13) facilitates nonhomologous end-joining and undergoes ATM-dependent hyperphosphorylation following ionizing radiation
- (2008) Chloe J. Macrae et al. DNA REPAIR
- Ku80 removal from DNA through double strand break–induced ubiquitylation
- (2008) Lisa Postow et al. JOURNAL OF CELL BIOLOGY
- Lymphocyte-Specific Compensation for XLF/Cernunnos End-Joining Functions in V(D)J Recombination
- (2008) Gang Li et al. MOLECULAR CELL
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started