Oncogenic BRAF disrupts thyroid morphogenesis and function via twist expression

ACTIVE SURVEILLANCE FOR PAPILLARY THYROID MICROCARCINOMA: NEW CHALLENGES AND OPPORTUNITIES FOR THE HEALTH CARE SYSTEM

(2016) Grace C. Haser et al.   Endocrine Practice

Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers

(2016) Iñigo Landa et al.   JOURNAL OF CLINICAL INVESTIGATION

CrispRVariants charts the mutation spectrum of genome engineering experiments

(2016) Helen Lindsay et al.   NATURE BIOTECHNOLOGY

Challenges of Active Surveillance Protocols for Low-Risk Papillary Thyroid Microcarcinoma in the United States

(2016) Grace C. Haser et al.   THYROID

BRAFV600E mutation in papillary thyroid microcarcinoma: a meta-analysis

(2015) F. Li et al.   ENDOCRINE-RELATED CANCER

Association Between BRAF V600E Mutation and Recurrence of Papillary Thyroid Cancer

(2015) Mingzhao Xing et al.   JOURNAL OF CLINICAL ONCOLOGY

Integrated Genomic Characterization of Papillary Thyroid Carcinoma

(2014) Nishant Agrawal et al.   CELL

BRAF activates and physically interacts with PAK to regulate cell motility

(2014) Samantha K McCarty et al.   ENDOCRINE-RELATED CANCER

Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

(2014) John A Zuris et al.   NATURE BIOTECHNOLOGY

p53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancer

(2014) D. G. McFadden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thyroid hormone-dependent adult pigment cell lineage and pattern in zebrafish

(2014) S. K. McMenamin et al.   SCIENCE

Profile of selumetinib and its potential in the treatment of melanoma

(2014) Sapna Patel et al.   OncoTargets and Therapy

Increased MAPK reactivation in early resistance to dabrafenib/trametinib combination therapy of BRAF-mutant metastatic melanoma

(2014) Georgina V. Long et al.   Nature Communications

V600EBRAF promotes invasiveness of thyroid cancer cells by decreasing E-cadherin expression through a Snail-dependent mechanism

(2013) Pablo Baquero et al.   CANCER LETTERS

Overexpression of HIF-2α, TWIST, and CXCR4 Is Associated with Lymph Node Metastasis in Papillary Thyroid Carcinoma

(2013) Ni Wang et al.   Clinical & Developmental Immunology

Molecular Pathways: Mitogen-Activated Protein Kinase Pathway Mutations and Drug Resistance

(2013) A. L. Pritchard et al.   CLINICAL CANCER RESEARCH

The zebrafish reference genome sequence and its relationship to the human genome

(2013) Kerstin Howe et al.   NATURE

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Incorporating RNA-seq data into the zebrafish Ensembl genebuild

(2012) J. E. Collins et al.   GENOME RESEARCH

Mutationally Activated BRAFV600E Elicits Papillary Thyroid Cancer in the Adult Mouse

(2011) R.-P. Charles et al.   CANCER RESEARCH

TWIST1 Plays a Pleiotropic Role in Determining the Anaplastic Thyroid Cancer Phenotype

(2011) Paolo Salerno et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation

(2011) Debyani Chakravarty et al.   JOURNAL OF CLINICAL INVESTIGATION

The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset

(2011) Craig J. Ceol et al.   NATURE

Progression of BRAF-induced thyroid cancer is associated with epithelial–mesenchymal transition requiring concomitant MAP kinase and TGFβ signaling

(2011) J A Knauf et al.   ONCOGENE

Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice

(2011) A. T. Franco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The BRAFV600E Oncogene Induces Transforming Growth Factor   Secretion Leading to Sodium Iodide Symporter Repression and Increased Malignancy in Thyroid Cancer

(2009) G. Riesco-Eizaguirre et al.   CANCER RESEARCH

V600EBRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway

(2009) C. A. Pratilas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA