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Scipion: A software framework toward integration, reproducibility and validation in 3D electron microscopy

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CTFFIND4: Fast and accurate defocus estimation from electron micrographs

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ClpB N-terminal domain plays a regulatory role in protein disaggregation

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The Cyclic Peptide Ecumicin Targeting ClpC1 Is Active against Mycobacterium tuberculosis In Vivo

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Lassomycin, a Ribosomally Synthesized Cyclic Peptide, Kills Mycobacterium tuberculosis by Targeting the ATP-Dependent Protease ClpC1P1P2

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Structural Dynamics of the MecA-ClpC Complex

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Activated ClpP kills persisters and eradicates a chronic biofilm infection

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Protein rescue from aggregates by powerful molecular chaperone machines

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Heat shock protein (Hsp) 70 is an activator of the Hsp104 motor

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Unraveling the Mechanism of Protein Disaggregation Through a ClpB-DnaK Interaction

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Disruption of Ionic Interactions between the Nucleotide Binding Domain 1 (NBD1) and Middle (M) Domain in Hsp100 Disaggregase Unleashes Toxic Hyperactivity and Partial Independence from Hsp70

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RELION: Implementation of a Bayesian approach to cryo-EM structure determination

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Hsp70 proteins bind Hsp100 regulatory M domains to activate AAA+ disaggregase at aggregate surfaces

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A tightly regulated molecular toggle controls AAA+ disaggregase

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The Natural Product Cyclomarin Kills Mycobacterium Tuberculosis by Targeting the ClpC1 Subunit of the Caseinolytic Protease

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ClpXP, an ATP-powered unfolding and protein-degradation machine

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Inactivation ofclpBin the Pathogen Leptospira interrogans Reduces Virulence and Resistance to Stress Conditions

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Structure and mechanism of the hexameric MecA–ClpC molecular machine

(2011) Feng Wang et al.   NATURE

Structure and function of the AAA+ protein CbbX, a red-type Rubisco activase

(2011) Oliver Mueller-Cajar et al.   NATURE

The antibiotic ADEP reprogrammes ClpP, switching it from a regulated to an uncontrolled protease

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