Article
Medicine, General & Internal
Chengyi Ding, Dara O'Neill, Steven Bell, Emmanuel Stamatakis, Annie Britton
Summary: The study found that light-to-moderate alcohol consumption is associated with the prognosis of patients with cardiovascular disease, showing a J-shaped association, with the risk reduction peaking before decreasing with increasing alcohol intake.
Article
Oncology
Gyeongsil Lee, Seogsong Jeong, Seulggie Choi, Kyae Hyung Kim, Jooyoung Chang, Seong Rae Kim, Kyuwoong Kim, Joung Sik Son, Sung Min Kim, Daein Choi, Sang Min Park
Summary: There was no association found between alcohol consumption and incident cardiovascular disease among long-term survivors of colorectal cancer. However, hazardous alcohol consumption was linked to an increased risk of ischemic and hemorrhagic stroke in comparison to non-drinkers. The study suggests that advising colorectal cancer survivors to avoid high alcohol consumption may be beneficial in reducing the risk of stroke.
Article
Cardiac & Cardiovascular Systems
Richard Kazibwe, Parag A. Chevli, Joni K. Evans, Matthew Allison, Erin D. Michos, Alexis C. Wood, Jingzhong Ding, Michael D. Shapiro, Morgana Mongraw-Chaffin
Summary: This study aimed to investigate the association between alcohol consumption and ectopic adiposity in adults at risk for cardiovascular disease. The results showed that heavy alcohol intake and binge drinking were associated with higher ectopic fat.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Review
Gastroenterology & Hepatology
Fredrik Aberg, Christopher D. Byrne, Carlos J. Pirola, Ville Mannisto, Silvia Sookoian
Summary: Alcohol use and metabolic syndrome frequently co-exist and are associated with various health problems including chronic liver disease and hepatocellular carcinoma. The effects of mild-moderate alcohol consumption on the risk of metabolic syndrome and fatty liver disease are unclear, with mixed results from studies. However, prospective studies indicate that mild-moderate alcohol use is associated with an increase in liver-related outcomes. Alcohol and metabolic factors independently and together contribute to liver-related outcomes, and components of metabolic syndrome have additive effects. Central/abdominal obesity measures may predict liver-related outcomes more accurately than BMI, even in individuals who consume harmful amounts of alcohol. The accumulating evidence highlights the multifactorial nature of liver disease and suggests the need for holistic approaches in risk prediction and treatment planning.
JOURNAL OF HEPATOLOGY
(2023)
Review
Nutrition & Dietetics
Cristian Statescu, Alexandra Clement, Ionela-Lacramioara Serban, Radu Sascau
Summary: Research has focused on modifiable risk factors for cardiovascular diseases, with alcohol intake having a biphasic impact, where low to moderate consumption may decrease adverse events, but excessive intake is harmful.
Article
Medicine, General & Internal
Frederick K. Ho, Lyn D. Ferguson, Carlos A. Celis-Morales, Stuart R. Gray, Ewan Forrest, William Alazawi, Jason M. R. Gill, Srinivasa Vittal Katikireddi, John G. F. Cleland, Paul Welsh, Jill P. Pell, Naveed Sattar
Summary: This study found that elevated GGT levels were associated with self-reported alcohol intake and adiposity markers. Higher GGT concentrations were related to liver-related, cardiovascular, and all-cause mortality. Adding GGT to risk algorithms improved the classification of cardiovascular mortality risk.
Article
Food Science & Technology
Qiao Kang, Jinyuan Sun, Bowen Wang, Baoguo Sun
Summary: Excessive alcohol consumption can cause chronic diseases, but alcohol beverages have been used as medicine ingredients in various cultures. Light-moderate alcohol consumption, regardless of the beverage type, is associated with reducing cardiovascular incidence and mortality rate. Different alcoholic beverages possess varying degrees of health effects due to differences in their non-ethanol component profiles.
FOOD SCIENCE AND HUMAN WELLNESS
(2023)
Review
Peripheral Vascular Disease
Flavio Danni Fuchs, Sandra Costa Fuchs
Summary: The study confirmed an acute biphasic effect of ethanol on blood pressure, but chronic alcohol consumption increases the risk of developing hypertension, especially for Blacks. The mechanism underlying the chronic effects of alcohol on blood pressure remains unclear.
CURRENT HYPERTENSION REPORTS
(2021)
Article
Nutrition & Dietetics
Trine Levring Wilkens, Zabrina Ziegler, Violetta Aru, Bekzod Khakimov, Snaedis Lilja Overgaard, Soren Balling Engelsen, Lars Ove Dragsted
Summary: Moderate alcohol consumption (1-2 drinks/day) may lower the risk of coronary heart disease, but the exact mechanisms are unclear. The MetAl trial found that moderate alcohol consumption for a few weeks led to changes in apoA1- and HDL-related biomarkers. Compared to abstention, moderate alcohol consumption increased total apoA1 more than HDL-C, and increased the cholesterol, apoA1, and phospholipid content of several HDL subfractions. Further research is needed to determine if this provides a cardiovascular benefit.
Article
Psychiatry
Minsoo Kim, Hyewon Kim, Kyungdo Han, Juhwan Yoo, Kyojin Yang, Hong Jin Jeon
Summary: This study examined the association between changes in alcohol consumption and cardiovascular diseases (CVDs) in patients with depression. The results showed that heavy drinkers had increased risks for myocardial infarction, ischemic stroke, composite CVDs, and all-cause mortality compared to non-drinkers. Additionally, those who started heavy drinking after the diagnosis of depression had increased risks of CVDs and all-cause mortality.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Review
Physiology
Huige Li, Ning Xia
Summary: Alcohol consumption has a complex relationship with cardiovascular risk, with heavy use and binge drinking harming cardiovascular health, while the effect of light-to-moderate alcohol consumption remains controversial. The type of alcoholic beverage consumed can also have varying effects on cardiovascular health, such as increasing HDL cholesterol and adiponectin levels, and reducing fibrinogen levels.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
(2023)
Review
Peripheral Vascular Disease
Anna G. Hoek, Sabine van Oort, Kenneth J. Mukamal, Joline W. J. Beulens
Summary: There is a clear link between excessive alcohol consumption and cardiovascular disease (CVD), but the effects of moderate alcohol consumption on CVD are still uncertain. Some studies have shown that moderate drinkers have a lower risk of coronary heart disease and myocardial infarction, but there is still ambiguity about the effects of alcohol on other CVDs and all-cause mortality. More research, including long-term randomized controlled trials, studies on genetic polymorphisms, and policy evaluations, is needed to provide the best available evidence.
CURRENT ATHEROSCLEROSIS REPORTS
(2022)
Article
Nutrition & Dietetics
Xinyuan Zhang, Yan Liu, Shanshan Li, Alice H. Lichtenstein, Shuohua Chen, Muzi Na, Susan Veldheer, Aijun Xing, Yanxiu Wang, Shouling Wu, Xiang Gao
Summary: Studies have shown a J-shaped relationship between alcohol intake and the risk of CVD, cancer, and mortality in Chinese adults, with the lowest risk observed at around 25g/week of alcohol consumption.
Article
Nutrition & Dietetics
Chunyu Hu, Chunyan Huang, Jianxin Li, Fangchao Liu, Keyong Huang, Zhongying Liu, Xueli Yang, Xiaoqing Liu, Jie Cao, Shufeng Chen, Hongfan Li, Chong Shen, Ling Yu, Xigui Wu, Ying Li, Dongsheng Hu, Jianfeng Huang, Xiangfeng Lu, Dongfeng Gu
Summary: This study finds a causal relationship between alcohol consumption and cardiovascular diseases (CVDs) and all-cause mortality in Chinese males. Light and moderate drinking can reduce the risk of CVDs and all-cause mortality. However, genetically predicted alcohol consumption shows a linear association with CVDs.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Review
Public, Environmental & Occupational Health
Inge A. T. van de Luitgaarden, Sabine van Oort, Emma J. Bouman, Linda J. Schoonmade, Ilse C. Schrieks, Diederick E. Grobbee, Yvonne T. van der Schouw, Susanna C. Larsson, Stephen Burgess, Adriana J. van Ballegooijen, N. Charlotte Onland-Moret, Joline W. J. Beulens
Summary: This systematic review examined the causal effects of moderate alcohol consumption on cardiometabolic health through Mendelian randomization studies, indicating null associations for cardiovascular disease and diabetes but a detrimental association with all-cause mortality. The variability in methodological quality across included studies currently impedes drawing definitive conclusions on this topic, with further advancements in Mendelian randomization methodology expected to enhance future research in this area.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Endocrinology & Metabolism
Seamus P. Whelton, John W. McEvoy, Mariana Lazo, Josef Coresh, Christie M. Ballantyne, Elizabeth Selvin
Article
Public, Environmental & Occupational Health
Sonsoles Fuentes, Usama Bilal, Inaki Galan, Joan R. Villalbi, Albert Espelt, Marina Bosque-Prous, Manuel Franco, Mariana Lazo
EUROPEAN JOURNAL OF PUBLIC HEALTH
(2017)
Article
Gastroenterology & Hepatology
Dong Hyun Sinn, Danbee Kang, Hye Ryoun Jang, Seonhye Gu, Soo Jin Cho, Seung Woon Paik, Seungho Ryu, Yoosoo Chang, Mariana Lazo, Eliseo Guallar, Juhee Cho, Geum-Youn Gwak
JOURNAL OF HEPATOLOGY
(2017)
Meeting Abstract
Cardiac & Cardiovascular Systems
Vasanth Sathiyakumar, Asieh Golozar, Mariana Lazo, Renato Quispe, Eliseo Guallar, Roger Blumenthal, Steven Jones, Seth Martin
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2017)
Article
Medicine, Research & Experimental
Ada M. Cuevas, Mariana Lazo, Isabel Zuniga, Fernando Carrasco, Jim J. Potter, Veronica Alvarez, Marcos Berry, Fernando Maluenda, Mario Ferrario, Jeanne M. Clark
METABOLIC SYNDROME AND RELATED DISORDERS
(2017)
Article
Multidisciplinary Sciences
Joshua W. Smith, Maria F. Kroker-Lobos, Mariana Lazo, Alvaro Rivera-Andrade, Patricia A. Egner, Heiner Wedemeyer, Olga Torres, Neal D. Freedman, Katherine A. McGlynn, Eliseo Guallar, John D. Groopman, Manuel Ramirez-Zea
Article
Public, Environmental & Occupational Health
Eboselume Akhuemonkhan, Mariana Lazo
PREVENTIVE MEDICINE
(2017)
Editorial Material
Medicine, General & Internal
Kenneth Mukamal, Mariana Lazo
BMJ-BRITISH MEDICAL JOURNAL
(2017)
Article
Cardiac & Cardiovascular Systems
Roberta Florido, Chiadi E. Ndumele, Lucia Kwak, Yuanjie Pang, Kunihiro Matsushita, Jennifer A. Schrack, Mariana Lazo, Vijay Nambi, Roger S. Blumenthal, Aaron R. Folsom, Josef Coresh, Christie M. Ballantyne, Elizabeth Selvin
JACC-HEART FAILURE
(2017)
Article
Multidisciplinary Sciences
Yun Soo Hong, Yoosoo Chang, Seungho Ryu, Miguel Cainzos-Achirica, Min-Jung Kwon, Yiyi Zhang, Yuni Choi, Jiin Ahn, Sanjay Rampal, Di Zhao, Roberto Pastor-Barriuso, Mariana Lazo, Hocheol Shin, Juhee Cho, Eliseo Guallar
SCIENTIFIC REPORTS
(2017)
Article
Medical Laboratory Technology
Chiadi E. Ndumele, Laura Cobb, Mariana Lazo, Natalie A. Bello, Amil Shah, Vijay Nambi, Roger S. Blumenthal, Gary Gerstenblith, Scott D. Solomon, Christie M. Ballantyne, Elizabeth Selvin, Josef Coresh
CLINICAL CHEMISTRY
(2018)
Meeting Abstract
Gastroenterology & Hepatology
Mariana Lazo, Menglu Liang, Jeanne M. Clark, James P. Hamilton, Elizabeth Selvin
Meeting Abstract
Endocrinology & Metabolism
Scott J. Pilla, Ashok Balasubramanyam, William C. Knowler, Mariana Lazo, David M. Nathan, Xavier Pi-Sunyer, Jeanne M. Clark, Nisa M. Maruthur
Article
Astronomy & Astrophysics
Matheus J. Lazo, Juilson Paiva, Joao T. S. Amaral, Gastao S. F. Frederico
