Decellularization Strategies for Regenerative Medicine: From Processing Techniques to Applications

Perfusion-decellularized skeletal muscle as a three-dimensional scaffold with a vascular network template

(2016) Jian Zhang et al.   BIOMATERIALS

Improvement of diaphragmatic performance through orthotopic application of decellularized extracellular matrix patch

(2016) M. Piccoli et al.   BIOMATERIALS

Decellularization of porcine articular cartilage explants and their subsequent repopulation with human chondroprogenitor cells

(2016) Lu Luo et al.   Journal of the Mechanical Behavior of Biomedical Materials

Trypsin as enhancement in cyclical tracheal decellularization: Morphological and biophysical characterization

(2016) D.M. Giraldo-Gomez et al.   Materials Science & Engineering C-Materials for Biological Applications

A recellularized human colon model identifies cancer driver genes

(2016) Huanhuan Joyce Chen et al.   NATURE BIOTECHNOLOGY

Mechanical properties of endothelialized fibroblast-derived vascular scaffolds stimulated in a bioreactor

(2015) Maxime Y. Tondreau et al.   Acta Biomaterialia

6-Month aortic valve implantation of an off-the-shelf tissue-engineered valve in sheep

(2015) Zeeshan Syedain et al.   BIOMATERIALS

Pediatric tubular pulmonary heart valve from decellularized engineered tissue tubes

(2015) Jay M. Reimer et al.   BIOMATERIALS

Engineered composite tissue as a bioartificial limb graft

(2015) Bernhard J. Jank et al.   BIOMATERIALS

Bioengineering Human Myocardium on Native Extracellular MatrixNovelty and Significance

(2015) Jacques P. Guyette et al.   CIRCULATION RESEARCH

Tissue vascularization through 3D printing: Will technology bring us flow?

(2015) S.J. Paulsen et al.   DEVELOPMENTAL DYNAMICS

Directing cell migration and organization via nanocrater-patterned cell-repellent interfaces

(2015) Hojeong Jeon et al.   NATURE MATERIALS

Decellularization of Fibroblast Cell Sheets for Natural Extracellular Matrix Scaffold Preparation

(2015) Qi Xing et al.   TISSUE ENGINEERING PART C-METHODS

Decellularized human liver as a natural 3D-scaffold for liver bioengineering and transplantation

(2015) Giuseppe Mazza et al.   Scientific Reports

Design and 3D Printing of Scaffolds and Tissues

(2015) Jia An et al.   Engineering

Recellularization of Decellularized Lung Scaffolds Is Enhanced by Dynamic Suspension Culture

(2015) Aurélie Crabbé et al.   PLoS One

Evaluation of decellularization protocols for production of tubular small intestine submucosa scaffolds for use in oesophageal tissue engineering

(2014) Omaer Syed et al.   Acta Biomaterialia

Immunogenicity in xenogeneic scaffold generation: Antigen removal vs. decellularization

(2014) Maelene L. Wong et al.   Acta Biomaterialia

Human decellularized adipose tissue scaffold as a model for breast cancer cell growth and drug treatments

(2014) Lina W. Dunne et al.   BIOMATERIALS

Dynamic decellularization and cross-linking of rat tracheal matrix

(2014) Silvia Baiguera et al.   BIOMATERIALS

Creating perfused functional vascular channels using 3D bio-printing technology

(2014) Vivian K. Lee et al.   BIOMATERIALS

Comparative decellularization and recellularization of normal versus emphysematous human lungs

(2014) Darcy E. Wagner et al.   BIOMATERIALS

Decellularized Periodontal Ligament Cell Sheets with Recellularization Potential

(2014) A. Farag et al.   JOURNAL OF DENTAL RESEARCH

Optimizing Recellularization of Whole Decellularized Heart Extracellular Matrix

(2014) Matthew J. Robertson et al.   PLoS One

Immunogenicity of Intensively Decellularized Equine Carotid Arteries Is Conferred by the Extracellular Matrix Protein Collagen Type VI

(2014) Ulrike Boeer et al.   PLoS One

Combining decellularized human adipose tissue extracellular matrix and adipose-derived stem cells for adipose tissue engineering

(2013) Lina Wang et al.   Acta Biomaterialia

Electrospun scaffolds for tissue engineering of vascular grafts

(2013) Anwarul Hasan et al.   Acta Biomaterialia

Decellularization of Human and Porcine Lung Tissues for Pulmonary Tissue Engineering

(2013) John D. O'Neill et al.   ANNALS OF THORACIC SURGERY

Perfusion-decellularized pancreas as a natural 3D scaffold for pancreatic tissue and whole organ engineering

(2013) Saik-Kia Goh et al.   BIOMATERIALS

Preservation of aortic root architecture and properties using a detergent-enzymatic perfusion protocol

(2013) Linda H. Friedrich et al.   BIOMATERIALS

Perfusion decellularization of human and porcine lungs: Bringing the matrix to clinical scale

(2013) Sarah Elizabeth Gilpin et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

The first tissue-engineered airway transplantation: 5-year follow-up results

(2013) Alessandro Gonfiotti et al.   LANCET

Biophysical regulation of epigenetic state and cell reprogramming

(2013) Timothy L. Downing et al.   NATURE MATERIALS

Regeneration and experimental orthotopic transplantation of a bioengineered kidney

(2013) Jeremy J Song et al.   NATURE MEDICINE

Detergent-Enzymatic Decellularization of Swine Blood Vessels: Insight on Mechanical Properties for Vascular Tissue Engineering

(2013) Alessandro F. Pellegata et al.   Biomed Research International

A Decellularization Methodology for the Production of a Natural Acellular Intestinal Matrix

(2013) Panagiotis Maghsoudlou et al.   Jove-Journal of Visualized Experiments

Biochemical changes caused by decellularization may compromise mechanical integrity of tracheal scaffolds

(2012) L. Partington et al.   Acta Biomaterialia

Human fibroblast-derived ECM as a scaffold for vascular tissue engineering

(2012) Jean-Michel Bourget et al.   BIOMATERIALS

Chondrogenic differentiation of bone marrow-derived mesenchymal stem cells induced by acellular cartilage sheets

(2012) Ji Xin Xue et al.   BIOMATERIALS

Decellularization methods of porcine kidneys for whole organ engineering using a high-throughput system

(2012) David C. Sullivan et al.   BIOMATERIALS

Classifying Surfactants with Respect to Their Effect on Lipid Membrane Order

(2012) Mozhgan Nazari et al.   BIOPHYSICAL JOURNAL

In vivocartilage repair using adipose-derived stem cell-loaded decellularized cartilage ECM scaffolds

(2012) Hongjun Kang et al.   Journal of Tissue Engineering and Regenerative Medicine

Detergent enzymatic treatment for the development of a natural acellular matrix for oesophageal regeneration

(2012) Giorgia Totonelli et al.   PEDIATRIC SURGERY INTERNATIONAL

Microarray with Micro- and Nano-topographies Enables Identification of the Optimal Topography for Directing the Differentiation of Primary Murine Neural Progenitor Cells

(2012) Aung Aung Kywe Moe et al.   Small

The effect of detergent-based decellularization procedures on cellular proteins and immunogenicity in equine carotid artery grafts

(2011) Ulrike Böer et al.   BIOMATERIALS

An overview of tissue and whole organ decellularization processes

(2011) Peter M. Crapo et al.   BIOMATERIALS

Matrix Composition and Mechanics of Decellularized Lung Scaffolds

(2011) Thomas H. Petersen et al.   CELLS TISSUES ORGANS

A Whole-Organ Regenerative Medicine Approach for Liver Replacement

(2011) Alejandro Soto-Gutierrez et al.   TISSUE ENGINEERING PART C-METHODS

Decellularization of pericardial tissue and its impact on tensile viscoelasticity and glycosaminoglycan content

(2010) Birzabith Mendoza-Novelo et al.   Acta Biomaterialia

Cellular cardiomyoplasty and cardiac tissue engineering for myocardial therapy☆

(2010) Feng Wang et al.   ADVANCED DRUG DELIVERY REVIEWS

The use of decellularized adipose tissue to provide an inductive microenvironment for the adipogenic differentiation of human adipose-derived stem cells

(2010) L.E. Flynn   BIOMATERIALS

A rabbit anterior cornea replacement derived from acellular porcine cornea matrix, epithelial cells and keratocytes

(2010) Kunpeng Pang et al.   BIOMATERIALS

The use of high-hydrostatic pressure treatment to decellularize blood vessels

(2010) Seiichi Funamoto et al.   BIOMATERIALS

Direct differentiation of human embryonic stem cells into selective neurons on nanoscale ridge/groove pattern arrays

(2010) Man Ryul Lee et al.   BIOMATERIALS

Preparation and characterization of decellularized cornea using high-hydrostatic pressurization for corneal tissue engineering

(2010) Yoshihide Hashimoto et al.   BIOMATERIALS

Impact of heart valve decellularization on 3-D ultrastructure, immunogenicity and thrombogenicity

(2010) Jianye Zhou et al.   BIOMATERIALS

A sandwich model for engineering cartilage with acellular cartilage sheets and chondrocytes

(2010) Yi Yi Gong et al.   BIOMATERIALS

The use of whole organ decellularization for the generation of a vascularized liver organoid

(2010) Pedro M. Baptista et al.   HEPATOLOGY

Fabrication of cardiac patch with decellularized porcine myocardial scaffold and bone marrow mononuclear cells

(2010) Bo Wang et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Direct application of supercritical carbon dioxide for the reduction of Cronobacter spp. (Enterobacter sakazakii) in end products of dehydrated powdered infant formula

(2010) S.A. Kim et al.   JOURNAL OF DAIRY SCIENCE

Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix

(2010) Basak E Uygun et al.   NATURE MEDICINE

Developing an Articular Cartilage Decellularization Process Toward Facet Joint Cartilage Replacement

(2010) Benjamin D. Elder et al.   NEUROSURGERY

Influence of Acellular Natural Lung Matrix on Murine Embryonic Stem Cell Differentiation and Tissue Formation

(2010) Joaquin Cortiella et al.   TISSUE ENGINEERING PART A

Comparison of Three Methods for the Derivation of a Biologic Scaffold Composed of Adipose Tissue Extracellular Matrix

(2010) Bryan N. Brown et al.   TISSUE ENGINEERING PART C-METHODS

Regenerative medicine as applied to solid organ transplantation: current status and future challenges

(2010) Giuseppe Orlando et al.   TRANSPLANT INTERNATIONAL

Electrospun materials as potential platforms for bone tissue engineering

(2009) Jun-Hyeog Jang et al.   ADVANCED DRUG DELIVERY REVIEWS

Potential use of supercritical carbon dioxide to decontaminate Escherichia coli O157:H7, Listeria monocytogenes, and Salmonella typhimurium in alfalfa sprouted seeds

(2009) W.Y. Jung et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Stem cell fate dictated solely by altered nanotube dimension

(2009) S. Oh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Processing Porcine Cornea for Biomedical Applications

(2009) Joo Youn Oh et al.   TISSUE ENGINEERING PART C-METHODS

Collagen fiber alignment and biaxial mechanical behavior of porcine urinary bladder derived extracellular matrix

(2008) Thomas W. Gilbert et al.   BIOMATERIALS

Substrate Modulus Directs Neural Stem Cell Behavior

(2008) Krishanu Saha et al.   BIOPHYSICAL JOURNAL

Cell removal with supercritical carbon dioxide for acellular artificial tissue

(2008) K. Sawada et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Clinical transplantation of a tissue-engineered airway

(2008) Paolo Macchiarini et al.   LANCET

Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart

(2008) Harald C Ott et al.   NATURE MEDICINE

A brief definition of regenerative medicine

(2007) Chris Mason et al.   Regenerative Medicine