Review
Pharmacology & Pharmacy
Gautam Sethi, Prangya Rath, Abhishek Chauhan, Anuj Ranjan, Renuka Choudhary, Seema Ramniwas, Katrin Sak, Diwakar Aggarwal, Isha Rani, Hardeep Singh Tuli
Summary: Due to the rising incidence rates of liver cancer and concerns regarding toxicity of current chemotherapy drugs, there is an increasing need for alternative treatment methods. Quercetin, a flavonoid found in fruits, vegetables, and herbs, has shown promising results in inducing apoptotic cell death in cancer cells. It targets apoptosis-related proteins and has the potential for chemoprevention. This review discusses the mechanisms of action, nanodelivery strategies, and other potential cellular effects of quercetin in liver cancer.
Review
Pharmacology & Pharmacy
Md. Mominur Rahman, Md. Taslim Sarker, Mst. Afroza Alam Tumpa, Md. Yamin, Tamanna Islam, Moon Nyeo Park, Md. Rezaul Islam, Abdur Rauf, Rohit Sharma, Simona Cavalu, Bonglee Kim
Summary: Cancer is caused by irregular cell division, but natural compounds have shown promising anticancer efficacy by targeting cellular signaling pathways to prevent cancer cell proliferation and development without harming normal cells.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Oncology
Emaan Haque, Abdullah Esmail, Ibrahim Muhsen, Haneen Salah, Maen Abdelrahim
Summary: Gastric cancer is the fifth most common tumor worldwide. Recent advancements have been made in the diagnosis and treatment of the disease, including improvements in non-invasive diagnostic techniques and the identification of new therapeutic targets. A multidisciplinary approach and cytotoxic chemotherapy are the main treatment options currently available.
Review
Pharmacology & Pharmacy
Abdullah K. Alshememry, Nasser B. Alsaleh, Nora Alkhudair, Rami Alzhrani, Aws Alshamsan
Summary: Pancreatic cancer is a lethal and incurable form of cancer with poor prognosis. Multidrug resistance is a significant challenge in its treatment. The development of nanocarriers that can target pancreatic cancer cells and minimize off-target effects is crucial. This review article provides an overview of pancreatic cancer and multidrug resistance, discusses recent advancements in nanocarrier development, and explores current challenges and potential future directions.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Nutrition & Dietetics
Ahyeon Kim, Jiwon Ha, Jeongeun Kim, Yongmin Cho, Jimyung Ahn, Chunhoo Cheon, Sung-Hoon Kim, Seong-Gyu Ko, Bonglee Kim
Summary: Natural products have potential effects in treating pancreatic cancer, particularly through inducing cell apoptosis. Plant extracts are the main focus in the research, while some natural products exhibit multifunctional properties.
Article
Environmental Sciences
A. K. Priya, Lalitha Gnanasekaran, P. Senthil Kumar, A. A. Jalil, Tuan K. A. Hoang, Saravanan Rajendran, Matias Soto-Moscoso, Deepanraj Balakrishnan
Summary: Nanoporous materials play a crucial role in electrocatalysis, nanodevice fabrication, energy and environmental research, and diagnostics, with nanoporous membranes being particularly valuable for water filtration applications. Research on nanoporous membranes for water treatment is important for developing novel and efficient water purification techniques.
Review
Food Science & Technology
Slim Smaoui, Hajer Ben Hlima, Olfa Ben Braiek, Karim Ennouri, Lotfi Mellouli, Amin Mousavi Khaneghah
Summary: Encapsulation is a valuable method for preserving aromatic compounds, enhancing thermal and oxidative stability, and expanding food applications. Encapsulation of plant bioactive compounds in meat products delays microbial growth and lipid/protein oxidation, offering a promising alternative for natural preservation in the meat industry.
Review
Chemistry, Analytical
Ebtesam Sobhanie, Foad Salehnia, Guobao Xu, Yalda Hamidipanah, Shayesteh Arshian, Ali Firoozbakhtian, Morteza Hosseini, Mohammad Reza Ganjali, Saima Hanif
Summary: Electrochemiluminescence-based biosensors are sensitive, cost-effective, and accurate techniques for virus detection. This article focuses on the recent trends and developments of these sensors in the field of virus detection, and introduces quantitative analysis of various viruses using specific biomarkers and biological receptors immobilized on ECL-based sensors.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Biophysics
Baljinder Kaur, Santosh Kumar, Brajesh Kumar Kaushik
Summary: Optical biosensors offer rapid, real-time, portable detection with low limits and high sensitivity for diagnosing various types of cancer. Recent advancements focus on the design of biosensors utilizing resonance, scattering, chemiluminescence, luminescence, and other techniques, as well as the development of two-dimensional materials and microfabrication technologies. Surface enhanced Raman spectroscopy and terahertz waves show promise for high specificity detection, while optical fiber platforms may drive the rapid development of biosensors due to their advantages in electromagnetic interference, size, multiplexing, and remote sensing capabilities.
BIOSENSORS & BIOELECTRONICS
(2022)
Review
Chemistry, Analytical
Madhusudan B. Kulkarni, Narasimha H. Ayachit, Tejraj M. Aminabhavi
Summary: In recent years, there has been significant advancement in the development of nanobiosensors, which are essential for various applications such as healthcare, environment, energy, electronics, and the food industry. Nanomaterials play a crucial role in sensing bioreceptors and developing biosensors with high selectivity and sensibility. However, the conventional methods are time-consuming and require skilled operators. Therefore, there is a great demand for the development of nanobiosensors that can be integrated with point-of-care-testing.
Review
Pharmacology & Pharmacy
Hardeep Singh Tuli, Hemant Joshi, Kanupriya Vashishth, Seema Ramniwas, Mehmet Varol, Manoj Kumar, Isha Rani, Vibha Rani, Katrin Sak
Summary: This review article discusses the anticancer properties of a natural biflavone compound called amentoflavone, derived from various plants such as ginkgo, hinoki, and St. John`s wort. It has been found to suppress malignant growth, induce apoptosis in tumor cells, and inhibit angiogenesis and metastasis. Amentoflavone shows promise as a potential lead compound for the development of novel anticancer drugs, and further in vivo studies and clinical trials are warranted.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
(2023)
Review
Pharmacology & Pharmacy
Xia He, Ning Wang, Yu Zhang, Xiaobo Huang, Yi Wang
Summary: Pancreatic cancer is a highly malignant tumor with a poor prognosis and low survival rate. Despite surgical resection and chemotherapy being used as the first-line treatment, the overall survival rates are still low. Therefore, there is an urgent need to develop alternative treatment strategies.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Eleonora Montuori, Caroline A. C. Hyde, Francesco Crea, Jon Golding, Chiara Lauritano
Summary: Prostate cancer is the most common cancer in men, and current diagnostic and treatment approaches have limitations. The scientific community is seeking new chemotherapeutic agents for this disease. This review focuses on compounds and extracts from marine organisms as potential sources of new drugs against prostate cancer.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Agricultural Engineering
Anil Kumar Patel, Reeta Rani Singhania, Sang Jun Sim, Cheng Di Dong
Summary: Mixotrophic cultivation strategy (MCS) has been shown to increase productivity of microalgae and is being extensively researched for biochemicals and biofuels production, but further development is needed to reach commercialization stage.
BIORESOURCE TECHNOLOGY
(2021)
Review
Immunology
Chae-Ok Yun, JinWoo Hong, A-Rum Yoon
Summary: Oncolytic viruses have gained attention in the pharmaceutical industry for their ability to induce and boost antitumor immunity through multiple mechanisms. These unique characteristics make oncolytic viruses promising in the field of immune-oncology.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Cell Biology
Liduo Yue, Yanbei Ren, Qingxi Yue, Zhou Ding, Kai Wang, Tiansheng Zheng, Guojie Chen, Xiangyun Chen, Ming Li, Lihong Fan
Summary: The study demonstrates that alpha-lipoic acid promotes apoptosis and exerts its antitumor activity against lung cancer by regulating mitochondrial energy metabolism enzyme-related antioxidative stress system. Downregulating the NRF2 antioxidant system is an important mechanism for LA to promote apoptosis.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
(2021)
