Journal
BIOMED RESEARCH INTERNATIONAL
Volume 2017, Issue -, Pages -Publisher
HINDAWI LTD
DOI: 10.1155/2017/5437139
Keywords
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Funding
- National Natural Science Foundation of China [31670114]
- Zhejiang Provincial Natural Science Foundation of China [LY16C010002]
- Regional Demonstration of Marine Economy Innovative Development Project, China [12PYY001SF08]
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Historically, the colistin has been thought to kill bacteria through membrane lysis. Here, we present an alternative mechanism that colistin induces rapid Paenibacillus polymyxa death through reactive oxygen species production. This significantly augments our understanding of the mechanism of colistin action, which is critical knowledge toward the yield development of colistin in the future.
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