Article
Engineering, Environmental
Yue Du, Shiwei Ai, Jie He, Huilin Gu, Xiaoxue Wang, Zhilan Li, Yuhui Dang
Summary: This study investigated the health risk of preschool children in a typical polluted area exposed to multiple sources of lead, including soil, water, rice, wheat, and vegetables. The results showed that the concentrations of lead in certain vegetables and soil exceeded the standards, indicating potential health risks. It is necessary to pay more attention to the food safety of vegetables in soil-polluted areas and take measures to reduce the health risks to preschool children.
ENVIRONMENTAL GEOCHEMISTRY AND HEALTH
(2023)
Article
Pediatrics
Xiao-Jun Cheng, Guang-Bo Li, Shuang-Shuang Zhang, Ying Liu, Yi-Chen Dong, Xue-Ning-Li
Summary: This study investigated the factors that affect blood lead levels (BLLs) in children in Shenyang and found that BLLs in children in Shenyang are still higher than in developed countries. Consumption of puffed grains and eggs is associated with higher BLLs, while often hand washing before meals may be protective against high BLLs.
Article
Environmental Sciences
A. S. Oliveira, E. A. C. Costa, E. C. Pereira, M. A. S. Freitas, B. M. Freire, B. L. Batista, M. S. Luz, K. P. K. Olympio
Summary: This study examined the applicability of preschool fingernail lead and cadmium as subchronic exposure biomarkers. It was found that abnormal appearance of nails was associated with high NLL and low NCL, indicating that preschool children may be co-exposed to both lead and cadmium.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Jie Dong, Xiaoping Li
Summary: Despite the phasing out of leaded gasoline in 2000, China still faces issues with child lead poisoning. The average blood lead levels of children in China remain above the safe limit, causing significant health problems. The Chinese government should develop stricter guidelines and implement effective policies to prevent and manage blood lead poisoning.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Yang Liu, Chengdong Xu, Feiyan Liu, Gexin Xiao, Shaoqi Zhou, Liming Huang, Ni Lin, Jianyi Li, Dong Chen, Qi Fu, Huijun Wang, Qingfeng Du
Summary: The study revealed that the development of the lead industry is associated with children's blood lead levels in different regions of China. Economic development in leaded areas was linked to inequity in children's BLLs, while in areas without lead industries, there was little correlation between economic development and children's BLLs.
ENVIRONMENTAL POLLUTION
(2022)
Article
Environmental Sciences
Su Zhen Wu, Huan Ying Xu, Ying Chen, Yu Chen, Qiao Ling Zhu, Min Hua Tan, Miao Miao Zhang
Summary: This study revealed a dose-effect relationship between low blood lead levels and preeclampsia, with a cut-off point at 4.2 μg/dl. There is a nonlinear association between blood lead levels and preeclampsia, with a significant increase in the risk of preeclampsia when blood lead levels exceed 4.2 μg/dl.
ENVIRONMENTAL RESEARCH
(2021)
Article
Pediatrics
Joseph M. Braun, Kimberly Yolton, Nicholas Newman, David E. Jacobs, Mark Taylor, Bruce P. Lanphear
Summary: The study found that the EPA's residential dust lead regulations place children at increased risk of lead poisoning, with the 2019 post-abatement lead clearance standards associated with higher risk compared to dust lead hazard standards. Extrapolating the findings to US children, it was estimated that the 2019 EPA standards could put up to 36,700 children at risk of lead poisoning.
PEDIATRIC RESEARCH
(2021)
Article
Environmental Sciences
Yared Beyene Yohannes, Shouta M. M. Nakayama, John Yabe, Haruya Toyomaki, Andrew Kataba, Hokuto Nakata, Kaampwe Muzandu, Yoshinori Ikenaka, Kennedy Choongo, Mayumi Ishizuka
Summary: Interindividual genetic variations, particularly in GST genes, are associated with heavy metal exposure in children and influence susceptibility to lead toxicity.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Review
Environmental Sciences
Jintao Huang, Zhijun Zeng, Xijin Xu, Qianwen Tian, Keyang Zheng, Xia Huo
Summary: Blood lead levels (BLLs) in e-waste-exposed children have been decreasing over time. A meta-analysis of 51 studies from six countries found that the total geometric mean BLL was 7.54 μg/dL. BLLs displayed a decreasing trend from 11.77 μg/dL in 2004-2006 to 4.63 μg/dL in 2016-2018. Nearly 95% of studies showed that e-waste-exposed children had significantly higher BLLs than the reference groups. The difference in BLLs between the exposure group and reference group decreased from 6.60 μg/dL in 2004 to 1.99 μg/dL in 2018. It was found that children from Guiyu had higher BLLs compared to other regions.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Review
Environmental Sciences
Jintao Huang, Zhijun Zeng, Xijin Xu, Qianwen Tian, Keyang Zheng, Xia Huo
Summary: Blood lead levels (BLLs) among children in e-waste recycling areas have been decreasing over time, but are still higher compared to children not exposed to e-waste. The difference in BLLs between exposed and reference groups is gradually decreasing.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Environmental Sciences
Shuo Wang, Yuan Jin, Jing Chen, Lin Lu, Yanan Li, Qianwen Zhao, Shuhua Bu, Xue Geng, Ge Guan, Weidong Qu, Yuxin Zheng, Jinglong Tang
Summary: The study investigated blood lead levels of over a million Chinese children and teenagers over the past 30 years, showing a declining trend with higher levels in boys compared to girls. Regions like Yunnan, Guizhou, and Shanxi had relatively high levels of lead exposure. Despite the decrease, Chinese children's lead levels are still higher than those in developed countries, indicating the need for more efforts in lead control for children.
ENVIRONMENTAL POLLUTION
(2021)
Article
Nutrition & Dietetics
Binshuo Hu, Shihua Tang, Zhuo Wang, Youhai Chen, Xiaohui Chen, Qian Zhao, Yu Jiang, Minghui Shen, Chong Zhang, Catherine Kaliszewski, Liang Wang, Ying Zhang
Summary: This study evaluated the status of dietary diversity, nutrient adequacy, blood biomarkers, and anthropometric status among preschool children in poor ethnic minority areas of northwest China. The findings showed that dietary diversity was associated with nutrient adequacy and other health outcomes. Factors such as living in urban areas, higher household wealth, and caregivers' nutritional knowledge were positively associated with dietary diversity, while living in urban areas, higher education of caregivers, and higher dietary diversity were positively associated with nutrient adequacy.
FRONTIERS IN NUTRITION
(2022)
Article
Pediatrics
Rohan Michael Ramesh, Avinash Ganesh Khiratkar, Kulandaipalayam Natarajan Sindhu, Anuradha Rose, Sushil Mathew John, Pundlik Rambhau Bhagat, Gagandeep Kang, Venkata Raghava Mohan
Summary: Low birth weight and household environment are important risk factors/hazards for elevated blood lead levels in urban preschool children. Multipronged interventions including government legislations, household environmental modification, safe water supply, and community education are crucial in reducing lead exposure in young children.
INDIAN JOURNAL OF PEDIATRICS
(2022)
Article
Environmental Sciences
Cleo Tebby, Julien Caudeville, Yasmil Fernandez, Celine Brochot
Summary: The decrease in lead levels in air and drinking water has resulted in a decrease in blood lead levels in children over the last 40 years, but there is still no known safe level of lead exposure for developmental effects. A study in France mapped predicted blood lead levels in children, finding that drinking water and food were the main sources of lead exposure, with the former being prominent in children over 2 years old. The study also showed discrepancies in predicted blood lead levels for infants and children aged 2 to 6, with the latter being more accurately predicted.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Xiang Yi, Shixiao Liu
Summary: This study examined the association between the growth rate of PTB and environmental impacting elements in the Pearl River Delta region and closed industry-related cities in China. It found that spring is the leading season for PTB incidence, and precipitation has a significant impact on the growth rate of PTB. Additionally, a lenient environmental policy may lead to rapid development of PTB growth rate, particularly when precipitation exceeds certain levels.
ENVIRONMENTAL RESEARCH
(2021)
Article
Environmental Sciences
Ju Wang, Lu-Lu Cao, Zhen-Yan Gao, Hong Zhang, Jun-Xia Liu, Su-Su Wang, Hui Pan, Chong-Huai Yan
Summary: This study investigated the associations of prenatal exposure to a mixture of OCPs, Hg, DHA, EPA and Se with thyroid hormone parameters in newborns, revealing dose-response relationships between mixture components and outcomes, but overall effects were not significant. The results suggest that prenatal exposure to p,p'-DDE, HCB and EPA as part of a mixture might affect thyroid function of newborns in independent and interactive ways, warranting further investigation into potential biological mechanisms.
ENVIRONMENTAL POLLUTION
(2022)
Article
Environmental Sciences
Su-Su Wang, An-Xin Lu, Lu-Lu Cao, Xiu-Fang Ran, Ya-Qian Wang, Chen Liu, Chong-Huai Yan
Summary: This study examined the impact of POPs exposure on birth outcomes. Findings showed adverse effects of prenatal exposure to HCB, β-HCH and p,p'-DDE on birth head circumference, particularly in girls. Further research is needed to explore gender differences and the effects of POPs on offspring growth and development.
ENVIRONMENTAL RESEARCH
(2022)
Article
Endocrinology & Metabolism
Yuexin Gan, Donghao Lu, Chonghuai Yan, Jun Zhang, Jian Zhao
Summary: This study used Mendelian randomization to investigate the causal effect of maternal PCOS on offspring birth weight, and found little evidence to support a significant impact of maternal PCOS on offspring weight.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Biochemistry & Molecular Biology
Chunping Hu, Susu Wang, Deqing Wu, Chonghuai Yan, Meiqin Wu
Summary: This study investigates the impact of subclinical hypothyroidism (SCH) during pregnancy on the spatial learning and memory ability of offspring, and finds that SCH inhibits the learning and memory ability of offspring, which may be related to the decreased expression of thyroid hormone receptor alpha (TRα).
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2022)
Article
Environmental Sciences
Yabin Hu, Jian Cheng, Yong Yin, Shijian Liu, Jianguo Tan, Shenghui Li, Meiqin Wu, Chonghuai Yan, Guangjun Yu, Yi Hu, Shilu Tong
Summary: The study found that both intra- and inter-day temperature variability may trigger childhood asthma, with higher diurnal temperature range having greater impacts in the cold season and temperature changes between neighboring days having bigger effects in the warm season.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Yihong Wang, Yaqian Wang, Chonghuai Yan
Summary: This study explored the influence of trace element levels on the intellectual development of school-aged children. The results showed a negative correlation between lead (Pb) and copper (Cu) levels in cord blood and children's cognitive abilities. Prenatal low-level exposure to arsenic (As) was found to adversely affect girls' intelligence quotient. Additionally, differences in selenium (Se) levels in blood were observed between boys and girls, with high Se levels associated with different effects on cognitive abilities based on gender.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Environmental Sciences
Chenyin Dong, Junxia Liu, Paul Harvey, Chonghuai Yan
Summary: Household dust is an important pathway for children's environmental Pb exposure. This study examines the Pb concentration and isotopic compositions in household dust samples from Shanghai, and finds that children living in lower priced homes have higher risk of Pb exposure. The data indicate that Pb in household dust is mainly derived from coal combustion and solid waste incineration.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Review
Environmental Sciences
Richard Fuller, Philip J. Landrigan, Kalpana Balakrishnan, Glynda Bathan, Stephan Bose-O'Reilly, Michael Brauer, Jack Caravanos, Tom Chiles, Aaron Cohen, Lilian Corra, Maureen Cropper, Greg Ferraro, Jill Hanna, David Hanrahan, Howard Hu, David Hunter, Gloria Janata, Rachael Kupka, Bruce Lanphear, Maureen Lichtveld, Keith Martin, Adetoun Mustapha, Ernesto Sanchez-Triana, Karti Sandilya, Laura Schaefli, Joseph Shaw, Jessica Seddon, William Suk, Martha Maria Tellez-Rojo, Chonghuai Yan
Summary: The Lancet Commission on pollution and health reported that pollution was responsible for 9 million premature deaths in 2015, making it the world's largest environmental risk factor for disease and premature death. Updated data from 2019 shows that pollution is still responsible for approximately 9 million deaths per year, with reductions in some types of pollution offset by increases in others. Despite efforts, little progress has been made in addressing pollution, particularly in low-income and middle-income countries.
LANCET PLANETARY HEALTH
(2022)
Article
Environmental Sciences
Yaqian Wang, Susu Wang, Yihong Wang, Anxin Lu, Lulu Cao, Ju Wang, Zhenyan Gao, Chonghuai Yan
Summary: This study investigated the prenatal exposure to arsenic and its effects on birth size in Wujiang City, Jiangsu, China. The results showed that low-level prenatal exposure to arsenic could have negative effects on birth weight, especially among male infants.
Article
Environmental Sciences
An-xin Lu, Su-su Wang, Xi Xu, Mei-qin Wu, Jun-xia Liu, Min Xu, Lu-Lu Cao, Ju Wang, Wei Wu, Hui Li, Chong-huai Yan
Summary: This study aimed to investigate the impact of cord blood lead on neurodevelopment in children within sex subgroups. The results showed that cord blood lead concentrations were negatively associated with fine motor scores in female children, but not in male children. Additionally, cord serum DHA levels were positively correlated with fine motor scores in male children. These findings suggest that prenatal lead exposure may lead to decreased motor function, but this phenomenon is only observed in female children. Furthermore, DHA may serve as a protective factor against lead exposure in boys. Further studies are needed to explore the associations between prenatal lead exposure and neurobehavioral development, as well as the mechanism of sex differences.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Environmental Sciences
Yabin Hu, Yiting Chen, Shijian Liu, Jianguo Tan, Guangjun Yu, Chonghuai Yan, Yong Yin, Shenghui Li, Shilu Tong
Summary: The interest in assessing the effects of exposure to greenspace on human health, especially asthma in children, has been increasing due to urbanization, physical inactivity, and air pollution. This study conducted a city-wide cross-sectional study in Shanghai, China, involving 16,605 children to investigate the association between residential greenspace and asthma. The study found that an increase in greenspace was associated with a decreased odds of asthma, and the association was modified by ambient temperature and residential area.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Hui Hua, Lihua Huang, Bo Yang, Shiwei Jiang, Yijing Zhang, Junxia Liu, Chonghuai Yan, Jian Xu
Summary: This study found that prenatal combined exposure to lead and stress had a greater impact on neurodevelopment, as well as on the composition of intestinal microbiota and the bidirectional communication with the central nervous system. Gut microbiota may mediate the effects of prenatal lead and stress co-exposure on neurodevelopmental deficits.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Environmental Sciences
Yabin Hu, Yiting Chen, Shijian Liu, Jianguo Tan, Guangjun Yu, Chonghuai Yan, Yong Yin, Shenghui Li, Shilu Tong
Summary: Previous studies on the link between greenspace exposure and childhood asthma have focused only on residential or school greenspace and have not considered the combined exposure at both homes and schools. This study conducted in Shanghai, China, found that increased greenspace exposure was associated with a lower risk of childhood asthma, and this association was modified by various socio-environmental factors.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Environmental Sciences
Yi-Hong Wang, Ya-Qian Wang, Xiao-Gang Yu, Yin Lin, Jun-Xia Liu, Wei-Ye Wang, Chong-Huai Yan
Summary: Juvenile zebrafish exposed to environmental arsenic showed behavioral abnormalities, including anxiety and social deficits, along with increased oxidative stress in the brain, decreased dopamine content, and altered gene transcription related to dopamine metabolism. However, treatment with N-acetylcysteine helped reduce oxidative stress and improve social behavior, dopamine levels, monoamine oxidase activity, and gene transcription in zebrafish.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Clinical Neurology
Ting Yu, Dongqing Xu, Jue Fan, Hui Hua, Xiangrong Guo, Yijing Zhang, Shiwei Jiang, Lihua Huang, Yining Jiang, Yuefen Wang, Chonghuai Yan, Jian Xu
Summary: This study found that high homework burdens were associated with neurobehavioral problems in adolescents. Sleep durations may mediate these associations, and sex may modify the relationships. The study collected information on homework burdens, bedtime/wake-up-time, and neurobehavioral problems from 609 middle-school students and identified patterns and associations through statistical analysis.
JOURNAL OF AFFECTIVE DISORDERS
(2023)