Rapid conversion of the ester prodrug abiraterone acetate results in intestinal supersaturation and enhanced absorption of abiraterone: In vitro, rat in situ and human in vivo studies

Title
Rapid conversion of the ester prodrug abiraterone acetate results in intestinal supersaturation and enhanced absorption of abiraterone: In vitro, rat in situ and human in vivo studies
Authors
Keywords
Ester prodrug, Intestinal perfusion, Human intestinal fluids, Intraluminal supersaturation, Abiraterone, Intraluminal degradation
Journal
Publisher
Elsevier BV
Online
2015-01-12
DOI
10.1016/j.ejpb.2015.01.001

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