Journal
BIOMATERIALS SCIENCE
Volume 5, Issue 8, Pages 1537-1540Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7bm00289k
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Funding
- NIH Director's New Innovator Award [1DP2HD087954-01]
- Glycoscience Common Fund [1R21AI129894-01]
- Program of Excellence in Glycosciences (PEG) [NHLBI: 4P01HL107150-06]
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We report a method for programming complexity into the glycocalyx of live cells. Via a combination of glycomaterial synthesis and membrane remodeling, we have engineered cells to display native-like, mixed sialoglycan populations, while confining the activity of each glycan into a specific nanoscale presentation.
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