Targeted delivery of geranylgeranylacetone to mitochondria by triphenylphosphonium modified nanoparticles: a promising strategy to prevent aminoglycoside-induced hearing loss

Bolaamphiphile-based nanocomplex delivery of phosphorothioate gapmer antisense oligonucleotides as a treatment for Clostridium difficile

(2016) John Hegarty et al.   International Journal of Nanomedicine

Effect of the Conjugation Density of Triphenylphosphonium Cation on the Mitochondrial Targeting of Poly(amidoamine) Dendrimers

(2015) Elizabeth R. Bielski et al.   MOLECULAR PHARMACEUTICS

Targeted delivery of doxorubicin to mitochondria using mesoporous silica nanoparticle nanocarriers

(2015) Qiuyu Qu et al.   Nanoscale

Zebrafish as tools for drug discovery

(2015) Calum A. MacRae et al.   NATURE REVIEWS DRUG DISCOVERY

Liposomal nanohybrid cerasomes for mitochondria-targeted drug delivery

(2015) Yanfang Wang et al.   Journal of Materials Chemistry B

Sustained release donepezil loaded PLGA microspheres for injection: Preparation, in vitro and in vivo study

(2015) Wenjia Guo et al.   Asian Journal of Pharmaceutical Sciences

Lipophilic Triphenylphosphonium Cations Inhibit Mitochondrial Electron Transport Chain and Induce Mitochondrial Proton Leak

(2015) Jan Trnka et al.   PLoS One

Design and Development of Novel Mitochondrial Targeted Nanocarriers, DQAsomes for Curcumin Inhalation

(2014) Špela Zupančič et al.   MOLECULAR PHARMACEUTICS

Caged oligonucleotides for bidirectional photomodulation of let-7 miRNA in zebrafish embryos

(2013) Julianne C. Griepenburg et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Screen of FDA-approved drug library reveals compounds that protect hair cells from aminoglycosides and cisplatin

(2012) Anna L. Vlasits et al.   HEARING RESEARCH

Liposomes loaded with paclitaxel and modified with novel triphenylphosphonium-PEG-PE conjugate possess low toxicity, target mitochondria and demonstrate enhanced antitumor effects in vitro and in vivo

(2012) Swati Biswas et al.   JOURNAL OF CONTROLLED RELEASE

In Vitro assessment of the utility of stearyl triphenyl phosphonium modified liposomes in overcoming the resistance of ovarian carcinoma Ovcar-3 cells to paclitaxel

(2012) Melani A. Solomon et al.   MITOCHONDRION

Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics

(2012) S. Marrache et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Considerations in the development of anin vitrodissolution condition for lacidipine tablets:in vivopharmacokinetic evaluation

(2011) Mingyu Sun et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Surface modification of liposomes with rhodamine-123-conjugated polymer results in enhanced mitochondrial targeting

(2011) Swati Biswas et al.   JOURNAL OF DRUG TARGETING

Functionalized nanosystems for targeted mitochondrial delivery

(2011) Shelley A. Durazo et al.   MITOCHONDRION

Geranylgeranylacetone ameliorates acute cochlear damage caused by 3-nitropropionic acid

(2010) Young Ho Kim et al.   NEUROTOXICOLOGY

Extracellular divalent cations modulate aminoglycoside-induced hair cell death in the zebrafish lateral line

(2009) Allison B. Coffin et al.   HEARING RESEARCH

Response of mechanosensory hair cells of the zebrafish lateral line to aminoglycosides reveals distinct cell death pathways

(2009) Kelly N. Owens et al.   HEARING RESEARCH

Multiple Triphenylphosphonium Cations Shuttle a Hydrophilic Peptide into Mitochondria

(2009) Shareefa E. Abu-Gosh et al.   MOLECULAR PHARMACEUTICS

Organelle-Targeted Nanocarriers: Specific Delivery of Liposomal Ceramide to Mitochondria Enhances Its Cytotoxicity in Vitro and in Vivo

(2008) Sarathi V. Boddapati et al.   NANO LETTERS