Journal
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
Volume 46, Issue 8, Pages 1694-1707Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/21691401.2017.1391820
Keywords
CNTF; retina; delivery; viral vectors; encapsulated cell technology
Categories
Funding
- Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran [95/2-3/1]
Ask authors/readers for more resources
The intraocular administration of the ciliary neurotrophic factor (CNTF) has been found to attenuate the photoreceptor degeneration and preserve retinal functions in the animal research models of the inherited or induced retinal disease. Studies with the aim of CNTF transfer to the posterior segment inside the eye have been directed to determine the best method for its administration. An ideal delivery method would overcome the eye drug elimination mechanisms or barriers and provide the sustained release of the CNTF into retina in the safest fashion with the minimum harm to the quality of life. This review focuses on the present state of CNTF delivery to retina, also provides an overview of available technologies and their challenges.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available