Plasma Biomarkers of Inflammation Reflect Seizures and Hemorrhagic Activity of Cerebral Cavernous Malformations

Co-expression of tissue factor and IL-6 in immature endothelial cells of cerebral cavernous malformations

(2017) Shouhei Noshiro et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Vascular permeability and iron deposition biomarkers in longitudinal follow-up of cerebral cavernous malformations

(2017) Romuald Girard et al.   JOURNAL OF NEUROSURGERY

“Pumping iron”—how macrophages handle iron at the systemic, microenvironmental, and cellular levels

(2017) Manfred Nairz et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Quantitative Susceptibility Mapping in Cerebral Cavernous Malformations: Clinical Correlations

(2016) H. Tan et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Peripheral plasma vitamin D and non-HDL cholesterol reflect the severity of cerebral cavernous malformation disease

(2016) Romuald Girard et al.   Biomarkers in Medicine

Serum matrix metalloproteinase-2: A potential biomarker for diagnosis of epilepsy

(2016) Rui Wang et al.   EPILEPSY RESEARCH

B-Cell Depletion Reduces the Maturation of Cerebral Cavernous Malformations in Murine Models

(2016) Changbin Shi et al.   Journal of Neuroimmune Pharmacology

Cerebral cavernous malformations arise from endothelial gain of MEKK3–KLF2/4 signalling

(2016) Zinan Zhou et al.   NATURE

How neuroinflammation contributes to neurodegeneration

(2016) R. M. Ransohoff   SCIENCE

Building a roadmap to biomarker qualification: challenges and opportunities

(2015) Shashi G Amur et al.   Biomarkers in Medicine

Biomarker Qualification: Toward a Multiple Stakeholder Framework for Biomarker Development, Regulatory Acceptance, and Utilization

(2015) S Amur et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Regulation of β1 Integrin-Klf2-Mediated Angiogenesis by CCM Proteins

(2015) Marc Renz et al.   DEVELOPMENTAL CELL

Vascular Permeability in Cerebral Cavernous Malformations

(2015) Abdul G Mikati et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Association of Cardiovascular Risk Factors with Disease Severity in Cerebral Cavernous Malformation Type 1 Subjects with the Common Hispanic Mutation

(2014) Hélène Choquet et al.   CEREBROVASCULAR DISEASES

Polymorphisms in Inflammatory and Immune Response Genes Associated with Cerebral Cavernous Malformation Type 1 Severity

(2014) Hélène Choquet et al.   CEREBROVASCULAR DISEASES

Lesions from patients with sporadic cerebral cavernous malformations harbor somatic mutations in the CCM genes: evidence for a common biochemical pathway for CCM pathogenesis

(2014) David A. McDonald et al.   HUMAN MOLECULAR GENETICS

Origin and Functions of Tissue Macrophages

(2014) Slava Epelman et al.   IMMUNITY

Immune complex formation and in situ B-cell clonal expansion in human cerebral cavernous malformations

(2014) Changbin Shi et al.   JOURNAL OF NEUROIMMUNOLOGY

Cerebrospinal fluid biomarkers in trials for Alzheimer and Parkinson diseases

(2014) Alberto Lleó et al.   Nature Reviews Neurology

Role of ROBO4 Signalling in Developmental and Pathological Angiogenesis

(2014) Suresh Singh Yadav et al.   Biomed Research International

Clinical significance of plasma VEGF value in ischemic stroke - research for biomarkers in ischemic stroke (REBIOS) study

(2013) Ryu Matsuo et al.   BMC Neurology

Disruption of the blood–brain barrier after generalized tonic-clonic seizures correlates with cerebrospinal fluid MMP-9 levels

(2013) Ya-Jun Li et al.   Journal of Neuroinflammation

Roles of Matrix Metalloproteinases and Their Targets in Epileptogenesis and Seizures

(2013) Hiroyuki Mizoguchi et al.   Clinical Psychopharmacology and Neuroscience

Untreated clinical course of cerebral cavernous malformations: a prospective, population-based cohort study

(2012) Rustam Al-Shahi Salman et al.   LANCET NEUROLOGY

Robo4-dependent Slit signaling stabilizes the vasculature during pathologic angiogenesis and cytokine storm

(2011) Nyall R London et al.   CURRENT OPINION IN HEMATOLOGY

In Vitro Characterization of the Angiogenic Phenotype and Genotype of the Endothelia Derived From Sporadic Cerebral Cavernous Malformations

(2011) Yuan Zhu et al.   NEUROSURGERY

Matrix Metalloproteinase-2 and -9 Secreted by Leukemic Cells Increase the Permeability of Blood-Brain Barrier by Disrupting Tight Junction Proteins

(2011) Saran Feng et al.   PLoS One

Conceptual and methodological issues relevant to cytokine and inflammatory marker measurements in clinical research

(2010) Xin Zhou et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Biology of interleukin-10

(2010) Robert Sabat et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Update on molecular diagnosis of hereditary hemorrhagic telangiectasia

(2010) Jennifer Richards-Yutz et al.   HUMAN GENETICS

Matrix Metalloproteinase-9 Mediates Hypoxia-Induced Vascular Leakage in the Brain via Tight Junction Rearrangement

(2010) Alexander T Bauer et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Vascular inflammation in central nervous system diseases: adhesion receptors controlling leukocyte-endothelial interactions

(2010) B. Rossi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cerebral cavernous malformation protein CCM1 inhibits sprouting angiogenesis by activating DELTA-NOTCH signaling

(2010) Joycelyn Wüstehube et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Matrix metalloproteinases and their multiple roles in neurodegenerative diseases

(2009) Gary A Rosenberg   LANCET NEUROLOGY

The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases

(2009) Kevin J Whitehead et al.   NATURE MEDICINE

Fasting and Nonfasting Lipid Levels

(2008) Anne Langsted et al.   CIRCULATION

A role for leukocyte-endothelial adhesion mechanisms in epilepsy

(2008) Paolo F Fabene et al.   NATURE MEDICINE

Hemorrhage From Cavernous Malformations of the Brain

(2008) Rustam Al-Shahi Salman et al.   STROKE