Preclinical Evaluation of the Efficacy of Antivenoms for Snakebite Envenoming: State-of-the-Art and Challenges Ahead
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Title
Preclinical Evaluation of the Efficacy of Antivenoms for Snakebite Envenoming: State-of-the-Art and Challenges Ahead
Authors
Keywords
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Journal
Toxins
Volume 9, Issue 5, Pages 163
Publisher
MDPI AG
Online
2017-05-16
DOI
10.3390/toxins9050163
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Note: Only part of the references are listed.- Proteomics and antivenomics of Papuan black snake ( Pseudechis papuanus ) venom with analysis of its toxicological profile and the preclinical efficacy of Australian antivenoms
- (2017) Davinia Pla et al. Journal of Proteomics
- Proteomic characterization and comparison of venoms from two elapid snakes (Bungarus multicinctus and Naja atra) from China
- (2016) Lin-Lin Shan et al. Journal of Proteomics
- Top-down venomics of the East African green mamba, Dendroaspis angusticeps , and the black mamba, Dendroaspis polylepis , highlight the complexity of their toxin arsenals
- (2016) Daniel Petras et al. Journal of Proteomics
- Neutralization of the neuromuscular inhibition of venom and taipoxin from the taipan ( Oxyuranus scutellatus ) by F(ab′) 2 and whole IgG antivenoms
- (2016) María Herrera et al. TOXICOLOGY LETTERS
- Immunoaffinity chromatography in antivenomics studies: Various parameters that can affect the results
- (2016) Kitisak Sintiprungrat et al. TOXICON
- Pathogenesis of dermonecrosis induced by venom of the spitting cobra, Naja nigricollis: An experimental study in mice
- (2016) Mario Rivel et al. TOXICON
- Preclinical evaluation of three polyspecific antivenoms against the venom of Echis ocellatus: Neutralization of toxic activities and antivenomics
- (2016) Juan J. Calvete et al. TOXICON
- An analysis of venom ontogeny and prey-specific toxicity in the Monocled Cobra (Naja kaouthia)
- (2016) Cassandra M. Modahl et al. TOXICON
- Venoms of Micrurus coral snakes: Evolutionary trends in compositional patterns emerging from proteomic analyses
- (2016) Bruno Lomonte et al. TOXICON
- Colubrid Venom Composition: An -Omics Perspective
- (2016) Inácio Junqueira-de-Azevedo et al. Toxins
- Cross-Neutralisation of In Vitro Neurotoxicity of Asian and Australian Snake Neurotoxins and Venoms by Different Antivenoms
- (2016) Anjana Silva et al. Toxins
- Rapid Radiations and the Race to Redundancy: An Investigation of the Evolution of Australian Elapid Snake Venoms
- (2016) Timothy Jackson et al. Toxins
- Efficacy of Indian polyvalent snake antivenoms against Sri Lankan snake venoms: lethality studies or clinically focussed in vitro studies
- (2016) Kalana Maduwage et al. Scientific Reports
- Constructing comprehensive venom proteome reference maps for integrative venomics
- (2015) Susann Eichberg et al. Expert Review of Proteomics
- Comparative venomics of the Prairie Rattlesnake (Crotalus viridis viridis) from Colorado: Identification of a novel pattern of ontogenetic changes in venom composition and assessment of the immunoreactivity of the commercial antivenom CroFab®
- (2015) Anthony J. Saviola et al. Journal of Proteomics
- Unveiling the nature of black mamba (Dendroaspis polylepis) venom through venomics and antivenom immunoprofiling: Identification of key toxin targets for antivenom development
- (2015) Andreas H. Laustsen et al. Journal of Proteomics
- The lethality test used for estimating the potency of antivenoms against Bothrops asper snake venom: Pathophysiological mechanisms, prophylactic analgesia, and a surrogate in vitro assay
- (2015) Francisco Chacón et al. TOXICON
- Evaluation of the preclinical efficacy of four antivenoms, distributed in sub-Saharan Africa, to neutralize the venom of the carpet viper, Echis ocellatus, from Mali, Cameroon, and Nigeria
- (2015) Laura V. Sánchez et al. TOXICON
- Snake venomics of monocled cobra (Naja kaouthia) and investigation of human IgG response against venom toxins
- (2015) Andreas H. Laustsen et al. TOXICON
- Selecting key toxins for focused development of elapid snake antivenoms and inhibitors guided by a Toxicity Score
- (2015) Andreas H. Laustsen et al. TOXICON
- A bright future for integrative venomics
- (2015) Juan J. Calvete et al. TOXICON
- Snake Venomics and Antivenomics of Bothrops diporus, a Medically Important Pitviper in Northeastern Argentina
- (2015) Carolina Gay et al. Toxins
- Proteomic and biochemical analyses of short-tailed pit viper (Gloydius brevicaudus) venom: Age-related variation and composition–activity correlation
- (2014) Jian-Fang Gao et al. Journal of Proteomics
- Immunological profile of antivenoms: Preclinical analysis of the efficacy of a polyspecific antivenom through antivenomics and neutralization assays
- (2014) José María Gutiérrez et al. Journal of Proteomics
- Venomous snakes of Costa Rica: Biological and medical implications of their venom proteomic profiles analyzed through the strategy of snake venomics
- (2014) Bruno Lomonte et al. Journal of Proteomics
- Medically important differences in snake venom composition are dictated by distinct postgenomic mechanisms
- (2014) N. R. Casewell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The analgesics morphine and tramadol do not alter the acute toxicity induced by Bothrops asper snake venom in mice
- (2014) José María Gutiérrez et al. TOXICON
- Comparative Studies of the Venom of a New Taipan Species, Oxyuranus temporalis, with Other Members of Its Genus
- (2014) Carmel Barber et al. Toxins
- Integrated “omics” profiling indicates that miRNAs are modulators of the ontogenetic venom composition shift in the Central American rattlesnake, Crotalus simus simus
- (2013) Jordi Durban et al. BMC GENOMICS
- Snake venomics: From the inventory of toxins to biology
- (2013) Juan J. Calvete TOXICON
- On the use of analgesia in experimental toxinology
- (2013) John Harris et al. TOXICON
- Use of immunoturbidimetry to detect venom–antivenom binding using snake venoms
- (2013) M.A. O'Leary et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- Cardiovascular Responses to Bothrops alternatus (Urutu) Snake Venom in Anesthetized Dogs
- (2012) Lourdes Dias et al. Cardiovascular Toxicology
- Comparative proteomic analysis of the venom of the taipan snake, Oxyuranus scutellatus, from Papua New Guinea and Australia: Role of neurotoxic and procoagulant effects in venom toxicity
- (2012) María Herrera et al. Journal of Proteomics
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- (2012) Mauren Villalta et al. Journal of Proteomics
- Nephrotoxicity of hump-nosed pit viper (Hypnale hypnale) venom in mice is preventable by the paraspecific Hemato polyvalent antivenom (HPA)
- (2012) Choo Hock Tan et al. TOXICON
- Renal effects and injury induced by animal toxins
- (2012) Visith Sitprija et al. TOXICON
- Second generation snake antivenomics: Comparing immunoaffinity and immunodepletion protocols
- (2012) Davinia Pla et al. TOXICON
- Improving antivenom availability and accessibility: Science, technology, and beyond
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- Assessing the preclinical efficacy of antivenoms: From the lethality neutralization assay to antivenomics
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- Proteomic tools against the neglected pathology of snake bite envenoming
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- Ending the drought: New strategies for improving the flow of affordable, effective antivenoms in Asia and Africa
- (2011) David J. Williams et al. Journal of Proteomics
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- (2011) Teresa Escalante et al. Journal of Proteomics
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- (2011) Soledad Bustillo et al. TOXICON
- Study of the design and analytical properties of the lethality neutralization assay used to estimate antivenom potency against Bothrops asper snake venom
- (2010) Gabriela Solano et al. BIOLOGICALS
- Life-threatening hyponatremia after krait bite envenoming – A new syndrome
- (2010) Jonas Höjer et al. CLINICAL TOXICOLOGY
- Snake Venomics of African Spitting Cobras: Toxin Composition and Assessment of Congeneric Cross-Reactivity of the Pan-African EchiTAb-Plus-ICP Antivenom by Antivenomics and Neutralization Approaches
- (2010) Daniel Petras et al. JOURNAL OF PROTEOME RESEARCH
- The Global Snake Bite Initiative: an antidote for snake bite
- (2010) David Williams et al. LANCET
- Snake bite
- (2010) David A Warrell LANCET
- Preclinical assessment of the neutralizing capacity of antivenoms produced in six Latin American countries against medically-relevant Bothrops snake venoms
- (2010) A. Segura et al. TOXICON
- Bothrops lanceolatus Bites: Guidelines for Severity Assessment and Emergent Management
- (2010) Dabor Resiere et al. Toxins
- Snake Venomics of the Central American RattlesnakeCrotalus simusand the South AmericanCrotalus durissusComplex Points to Neurotoxicity as an Adaptive Paedomorphic Trend alongCrotalusDispersal in South America
- (2009) Juan J. Calvete et al. JOURNAL OF PROTEOME RESEARCH
- Snake venomics and antivenomics: Proteomic tools in the design and control of antivenoms for the treatment of snakebite envenoming
- (2009) José María Gutiérrez et al. Journal of Proteomics
- Experimental pathophysiology of systemic alterations induced by Bothrops asper snake venom
- (2009) José María Gutiérrez et al. TOXICON
- Cross-neutralisation of Australian brown snake, taipan and death adder venoms by monovalent antibodies
- (2009) Geoffrey K. Isbister et al. VACCINE
- Snake Venomics of the Lancehead PitviperBothrops asper: Geographic, Individual, and Ontogenetic Variations
- (2008) Alberto Alape-Girón et al. JOURNAL OF PROTEOME RESEARCH
- Snake Venomics and Antivenomics of the Arboreal Neotropical Pitvipers Bothriechis lateralis and Bothriechis schlegelii
- (2008) Bruno Lomonte et al. JOURNAL OF PROTEOME RESEARCH
- Failure of a new antivenom to treat Echis ocellatus snake bite in rural Ghana: the importance of quality surveillance
- (2008) L.E. Visser et al. TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE
- The Global Burden of Snakebite: A Literature Analysis and Modelling Based on Regional Estimates of Envenoming and Deaths
- (2008) Anuradhani Kasturiratne et al. PLOS MEDICINE
- Potency evaluation of antivenoms in Brazil: The national control laboratory experience between 2000 and 2006
- (2007) H.P. Araujo et al. TOXICON
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