Structural and functional roles of ether lipids

Interaction of plasmenylcholine with free radicals in selected model systems

(2017) A. Broniec et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protective role of endogenous plasmalogens against hepatic steatosis and steatohepatitis in mice

(2017) Jung Eun Jang et al.   HEPATOLOGY

VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis

(2017) Rong Hua et al.   JOURNAL OF CELL BIOLOGY

Specific circulating phospholipids, acylcarnitines, amino acids and biogenic amines are aerobic exercise markers

(2017) Thomas K. Felder et al.   JOURNAL OF SCIENCE AND MEDICINE IN SPORT

Plasma Lipidomic Profiles Improve on Traditional Risk Factors for the Prediction of Cardiovascular Events in Type 2 Diabetes MellitusClinical Perspective

(2016) Zahir H. Alshehry et al.   CIRCULATION

Unbiased Metabolite Profiling of Schizophrenia Fibroblasts under Stressful Perturbations Reveals Dysregulation of Plasmalogens and Phosphatidylcholines

(2016) Joanne H. Huang et al.   JOURNAL OF PROTEOME RESEARCH

Remodeling of the postsynaptic plasma membrane during neural development

(2016) Karolina Tulodziecka et al.   MOLECULAR BIOLOGY OF THE CELL

Peroxisome biogenesis disorders in the Zellweger spectrum: An overview of current diagnosis, clinical manifestations, and treatment guidelines

(2016) Nancy E. Braverman et al.   MOLECULAR GENETICS AND METABOLISM

C13orf31 (FAMIN) is a central regulator of immunometabolic function

(2016) M Zaeem Cader et al.   NATURE IMMUNOLOGY

Membrane lipidomics in schizophrenia patients: a correlational study with clinical and cognitive manifestations

(2016) C Tessier et al.   Translational Psychiatry

Neuronal Orphan G-Protein Coupled Receptor Proteins Mediate Plasmalogens-Induced Activation of ERK and Akt Signaling

(2016) Md. Shamim Hossain et al.   PLoS One

Discovery of Inhibitors for the Ether Lipid-Generating Enzyme AGPS as Anti-Cancer Agents

(2015) Valentina Piano et al.   ACS Chemical Biology

Plasmalogen modulation attenuates atherosclerosis in ApoE- and ApoE/GPx1-deficient mice

(2015) Aliki A. Rasmiena et al.   ATHEROSCLEROSIS

Peroxisomal Lipid Synthesis Regulates Inflammation by Sustaining Neutrophil Membrane Phospholipid Composition and Viability

(2015) Irfan J. Lodhi et al.   Cell Metabolism

Plasmalogen phospholipids protect internodal myelin from oxidative damage

(2015) Adrienne M. Luoma et al.   FREE RADICAL BIOLOGY AND MEDICINE

A novel type of rhizomelic chondrodysplasia punctata, RCDP5, is caused by loss of the PEX5 long isoform

(2015) Tuva Barøy et al.   HUMAN MOLECULAR GENETICS

A Healthy Nordic Diet Alters the Plasma Lipidomic Profile in Adults with Features of Metabolic Syndrome in a Multicenter Randomized Dietary Intervention

(2015) Maria Lankinen et al.   JOURNAL OF NUTRITION

Extrinsic plasmalogens suppress neuronal apoptosis in mouse neuroblastoma Neuro-2A cells: importance of plasmalogen molecular species

(2015) Shinji Yamashita et al.   RSC Advances

A Peroxisomal Disorder of Severe Intellectual Disability, Epilepsy, and Cataracts Due to Fatty Acyl-CoA Reductase 1 Deficiency

(2014) Rebecca Buchert et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Lipidomic analysis of the liver from high-fat diet induced obese mice identifies changes in multiple lipid classes

(2014) Kristina Eisinger et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Peripheral nervous system plasmalogens regulate Schwann cell differentiation and myelination

(2014) Tiago Ferreira da Silva et al.   JOURNAL OF CLINICAL INVESTIGATION

Topogenesis and Homeostasis of Fatty Acyl-CoA Reductase 1

(2013) Masanori Honsho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plasmalogens Rescue Neuronal Cell Death through an Activation of AKT and ERK Survival Signaling

(2013) Md. Shamim Hossain et al.   PLoS One

Ether lipid generating enzyme AGPS alters the balance of structural and signaling lipids to fuel cancer pathogenicity

(2013) D. I. Benjamin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domains

(2013) R. Volmer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The importance of ether-phospholipids: A view from the perspective of mouse models

(2012) Tiago Ferreira da Silva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Functions of plasmalogen lipids in health and disease

(2012) Nancy E. Braverman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Inhibiting Adipose Tissue Lipogenesis Reprograms Thermogenesis and PPARγ Activation to Decrease Diet-Induced Obesity

(2012) Irfan J. Lodhi et al.   Cell Metabolism

Impaired neurotransmission in ether lipid-deficient nerve terminals

(2012) Alexander Brodde et al.   HUMAN MOLECULAR GENETICS

Obesity-Dependent Metabolic Signatures Associated with Nonalcoholic Fatty Liver Disease Progression

(2012) J. Barr et al.   JOURNAL OF PROTEOME RESEARCH

Peroxisome-derived lipids are self antigens that stimulate invariant natural killer T cells in the thymus

(2012) Federica Facciotti et al.   NATURE IMMUNOLOGY

Interactions of plasmalogens and their diacyl analogs with singlet oxygen in selected model systems

(2011) Agnieszka Broniec et al.   FREE RADICAL BIOLOGY AND MEDICINE

Identification of a New Fatty Acid Synthesis-Transport Machinery at the Peroxisomal Membrane

(2011) Merle Hillebrand et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plasmalogen synthesis is regulated via alkyl-dihydroxyacetonephosphate-synthase by amyloid precursor protein processing and is affected in Alzheimer’s disease

(2011) Marcus O. W. Grimm et al.   JOURNAL OF NEUROCHEMISTRY

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(2011) Noemi Fabelo et al.   MOLECULAR MEDICINE

Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity

(2011) Suneng Fu et al.   NATURE

Alkyl-Glycerol Rescues Plasmalogen Levels and Pathology of Ether-Phospholipid Deficient Mice

(2011) Pedro Brites et al.   PLoS One

Association of Lipidome Remodeling in the Adipocyte Membrane with Acquired Obesity in Humans

(2011) Kirsi H. Pietiläinen et al.   PLOS BIOLOGY

The Kennedy pathway-De novo synthesis of phosphatidylethanolamine and phosphatidylcholine

(2010) Federica Gibellini et al.   IUBMB LIFE

The Role of Plasmalogen in the Oxidative Stability of Neutral Lipids and Phospholipids

(2010) Guang Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Circulating plasmalogen levels and Alzheimer Disease Assessment Scale–Cognitive scores in Alzheimer patients

(2010) Paul Wood   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Disruption of blood-testis barrier dynamics in ether-lipid-deficient mice

(2009) Dorde Komljenovic et al.   CELL AND TISSUE RESEARCH

The plasma lipidomic signature of nonalcoholic steatohepatitis

(2009) Puneet Puri et al.   HEPATOLOGY

Defects in myelination, paranode organization and Purkinje cell innervation in the ether lipid-deficient mouse cerebellum

(2009) Andre Teigler et al.   HUMAN MOLECULAR GENETICS

Top-Down Lipidomics Reveals Ether Lipid Deficiency in Blood Plasma of Hypertensive Patients

(2009) Juergen Graessler et al.   PLoS One

The Vinyl Ether Linkages of Plasmalogens Are Favored Targets for Myeloperoxidase-Derived Oxidants: A Kinetic Study†

(2008) Ojia Skaff et al.   BIOCHEMISTRY

Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes

(2008) Matej Orešič et al.   JOURNAL OF EXPERIMENTAL MEDICINE