Interference with the production of infectious viral particles and bimodal inhibition of replication are broadly conserved antiviral properties of IFITMs

Δ20 IFITM2 differentially restricts X4 and R5 HIV-1

(2017) Wan-Lin Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resistance of Transmitted Founder HIV-1 to IFITM-Mediated Restriction

(2016) Toshana L. Foster et al.   Cell Host & Microbe

Natural mutations in IFITM3 modulate post‐translational regulation and toggle antiviral specificity

(2016) Alex A Compton et al.   EMBO REPORTS

The Interferon-Stimulated Gene IFITM3 Restricts Infection and Pathogenesis of Arthritogenic and Encephalitic Alphaviruses

(2016) Subhajit Poddar et al.   JOURNAL OF VIROLOGY

The Interferon-Stimulated GeneIfitm3Restricts West Nile Virus Infection and Pathogenesis

(2016) Matthew J. Gorman et al.   JOURNAL OF VIROLOGY

Virion Background and Efficiency of Virion Incorporation Determine Susceptibility of Simian Immunodeficiency Virus Env-Driven Viral Entry to Inhibition by IFITM Proteins

(2016) Florian Wrensch et al.   JOURNAL OF VIROLOGY

Nonhuman Primate IFITM Proteins Are Potent Inhibitors of HIV and SIV

(2016) Jordan Wilkins et al.   PLoS One

Alphavirus Restriction by IFITM Proteins

(2016) Stuart Weston et al.   TRAFFIC

The IFITMs Inhibit Zika Virus Replication

(2016) George Savidis et al.   Cell Reports

Antiviral Role of IFITM Proteins in African Swine Fever Virus Infection

(2016) Raquel Muñoz-Moreno et al.   PLoS One

The Interferon-induced Transmembrane Proteins, IFITM1, IFITM2, and IFITM3 Inhibit Hepatitis C Virus Entry

(2015) Sumudu K. Narayana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Primate lentiviruses are differentially inhibited by interferon-induced transmembrane proteins

(2015) Jin Qian et al.   VIROLOGY

IFITM Proteins Restrict HIV-1 Infection by Antagonizing the Envelope Glycoprotein

(2015) Jingyou Yu et al.   Cell Reports

Comparative Analysis of Cesium Chloride- and Iodixanol-Based Purification of Recombinant Adeno-Associated Viral Vectors for Preclinical Applications

(2015) Benjamin Strobel et al.   Human Gene Therapy Methods

Human Cytomegalovirus Exploits Interferon-Induced Transmembrane Proteins To Facilitate Morphogenesis of the Virion Assembly Compartment

(2015) Maorong Xie et al.   JOURNAL OF VIROLOGY

IFITM Proteins Incorporated into HIV-1 Virions Impair Viral Fusion and Spread

(2014) Alex A. Compton et al.   Cell Host & Microbe

Human respiratory syncytial virus infection is inhibited by IFN-induced transmembrane proteins

(2014) W. Zhang et al.   JOURNAL OF GENERAL VIROLOGY

Postentry Restriction of Mason-Pfizer Monkey Virus in Mouse Cells

(2014) Gary Z. Wang et al.   JOURNAL OF VIROLOGY

The Antiviral Restriction Factors IFITM1, 2 and 3 Do Not Inhibit Infection of Human Papillomavirus, Cytomegalovirus and Adenovirus

(2014) Cody J. Warren et al.   PLoS One

A Membrane Topology Model for Human Interferon Inducible Transmembrane Protein 1

(2014) Stuart Weston et al.   PLoS One

IFITM proteins are incorporated onto HIV-1 virion particles and negatively imprint their infectivity

(2014) Kevin Tartour et al.   Retrovirology

HIV-1 mutates to evade IFITM1 restriction

(2014) Shilei Ding et al.   VIROLOGY

IFITM Proteins Inhibit Entry Driven by the MERS-Coronavirus Spike Protein: Evidence for Cholesterol-Independent Mechanisms

(2014) Florian Wrensch et al.   Viruses-Basel

IFITM3 Restricts Influenza A Virus Entry by Blocking the Formation of Fusion Pores following Virus-Endosome Hemifusion

(2014) Tanay M. Desai et al.   PLoS Pathogens

The Antiviral Effector IFITM3 Disrupts Intracellular Cholesterol Homeostasis to Block Viral Entry

(2013) Samad Amini-Bavil-Olyaee et al.   Cell Host & Microbe

Regulation of the Bone-restricted IFITM-like (Bril) Gene Transcription by Sp and Gli Family Members and CpG Methylation

(2013) Bahar Kasaai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interferon-induced Transmembrane Protein 3 Is a Type II Transmembrane Protein

(2013) Charles C. Bailey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interferon-inducible Transmembrane Protein 3 (IFITM3) Restricts Reovirus Cell Entry

(2013) Amanda A. Anafu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IFITMs Restrict the Replication of Multiple Pathogenic Viruses

(2013) Jill M. Perreira et al.   JOURNAL OF MOLECULAR BIOLOGY

IFITM-2 and IFITM-3 but Not IFITM-1 Restrict Rift Valley Fever Virus

(2013) R. Mudhasani et al.   JOURNAL OF VIROLOGY

The CD225 Domain of IFITM3 Is Required for both IFITM Protein Association and Inhibition of Influenza A Virus and Dengue Virus Replication

(2013) S. P. John et al.   JOURNAL OF VIROLOGY

Defining the Range of Pathogens Susceptible to Ifitm3 Restriction Using a Knockout Mouse Model

(2013) Aaron R. Everitt et al.   PLoS One

Amphotericin B Increases Influenza A Virus Infection by Preventing IFITM3-Mediated Restriction

(2013) Tsai-Yu Lin et al.   Cell Reports

Intermediate conformations during viral fusion glycoprotein structural transition

(2013) Eduard Baquero et al.   Current Opinion in Virology

IFITM Proteins Restrict Viral Membrane Hemifusion

(2013) Kun Li et al.   PLoS Pathogens

Short-Range Exosomal Transfer of Viral RNA from Infected Cells to Plasmacytoid Dendritic Cells Triggers Innate Immunity

(2012) Marlène Dreux et al.   Cell Host & Microbe

The N-Terminal Region of IFITM3 Modulates Its Antiviral Activity by Regulating IFITM3 Cellular Localization

(2012) R. Jia et al.   JOURNAL OF VIROLOGY

IFITM3 restricts the morbidity and mortality associated with influenza

(2012) Aaron R. Everitt et al.   NATURE

Ifitm3 Limits the Severity of Acute Influenza in Mice

(2012) Charles C. Bailey et al.   PLoS Pathogens

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

(2011) Nadine Laguette et al.   NATURE

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

(2011) Kasia Hrecka et al.   NATURE

A simple, versatile and efficient method to genetically modify human monocyte-derived dendritic cells with HIV-1–derived lentiviral vectors

(2011) Grégory Berger et al.   Nature Protocols

Cell entry of enveloped viruses

(2011) Richard K Plemper   Current Opinion in Virology

Distinct Patterns of IFITM-Mediated Restriction of Filoviruses, SARS Coronavirus, and Influenza A Virus

(2011) I-Chueh Huang et al.   PLoS Pathogens

Interferon-Induced Cell Membrane Proteins, IFITM3 and Tetherin, Inhibit Vesicular Stomatitis Virus Infection via Distinct Mechanisms

(2010) J. M. Weidner et al.   JOURNAL OF VIROLOGY

The IFITM Proteins Inhibit HIV-1 Infection

(2010) J. Lu et al.   JOURNAL OF VIROLOGY

Palmitoylome profiling reveals S-palmitoylation–dependent antiviral activity of IFITM3

(2010) Jacob S Yount et al.   Nature Chemical Biology

The IFITM Proteins Mediate Cellular Resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus

(2009) Abraham L. Brass et al.   CELL

HIV Enters Cells via Endocytosis and Dynamin-Dependent Fusion with Endosomes

(2009) Kosuke Miyauchi et al.   CELL

Ebolavirus Glycoprotein GP Masks both Its Own Epitopes and the Presence of Cellular Surface Proteins

(2009) O. Reynard et al.   JOURNAL OF VIROLOGY

Role of Ebola Virus VP30 in Transcription Reinitiation

(2008) M. J. Martinez et al.   JOURNAL OF VIROLOGY

Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

(2008) B. F. Keele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA