Early Antiretroviral Therapy Is Associated with Lower HIV DNA Molecular Diversity and Lower Inflammation in Cerebrospinal Fluid but Does Not Prevent the Establishment of Compartmentalized HIV DNA Populations

HIV-associated neurocognitive disorder — pathogenesis and prospects for treatment

(2016) Deanna Saylor et al.   Nature Reviews Neurology

Residual inflammation and viral reservoirs

(2016) Marta Massanella et al.   Current Opinion in HIV and AIDS

Early antiretroviral therapy with raltegravir generates sustained reductions in HIV reservoirs but not lower T-cell activation levels

(2015) William J. Hey-Cunningham et al.   AIDS

Next generation sequencing improves detection of drug resistance mutations in infants after PMTCT failure

(2015) Randall G. Fisher et al.   JOURNAL OF CLINICAL VIROLOGY

Circulating HIV DNA Correlates With Neurocognitive Impairment in Older HIV-infected Adults on Suppressive ART

(2015) Michelli Faria de Oliveira et al.   Scientific Reports

Compartmentalized Replication of R5 T Cell-Tropic HIV-1 in the Central Nervous System Early in the Course of Infection

(2015) Christa Buckheit Sturdevant et al.   PLoS Pathogens

Compartmentalization, Viral Evolution, and Viral Latency of HIV in the CNS

(2015) Maria M. Bednar et al.   Current HIV/AIDS Reports

Amount of HIV DNA in Peripheral Blood Mononuclear Cells is Proportional to the Severity of HIV-1-Associated Neurocognitive Disorders

(2014) Bruce Shiramizu et al.   JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES

Elevated sCD163 in plasma but not cerebrospinal fluid is a marker of neurocognitive impairment in HIV infection

(2013) Tricia H. Burdo et al.   AIDS

Analysis of HIV Quasispecies Suggests Compartmentalization in the Liver

(2013) Patricia K. Penton et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Evaluation of an HIV Nucleic Acid Testing Program With Automated Internet and Voicemail Systems to Deliver Results

(2013) Sheldon R. Morris   ANNALS OF INTERNAL MEDICINE

Long-term antiretroviral therapy initiated during primary HIV-1 infection is key to achieving both low HIV reservoirs and normal T cell counts

(2013) Laurent Hocqueloux et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Human Immunodeficiency Viruses Appear Compartmentalized to the Female Genital Tract in Cross-Sectional Analyses but Genital Lineages Do Not Persist Over Time

(2013) Marta E. Bull et al.   JOURNAL OF INFECTIOUS DISEASES

Antiretroviral Therapy Initiated Within 6 Months of HIV Infection Is Associated With Lower T-Cell Activation and Smaller HIV Reservoir Size

(2013) Vivek Jain et al.   JOURNAL OF INFECTIOUS DISEASES

Molecular and pathologic insights from latent HIV-1 infection in the human brain

(2013) P. Desplats et al.   NEUROLOGY

Enhanced CD4+ T-Cell Recovery with Earlier HIV-1 Antiretroviral Therapy

(2013) Tuan Le et al.   NEW ENGLAND JOURNAL OF MEDICINE

Highly Precise Measurement of HIV DNA by Droplet Digital PCR

(2013) Matthew C. Strain et al.   PLoS One

HIV DNA Reservoir Increases Risk for Cognitive Disorders in cART-Naïve Patients

(2013) Victor G. Valcour et al.   PLoS One

Central Nervous System Compartmentalization of HIV-1 Subtype C Variants Early and Late in Infection in Young Children

(2013) Christa Buckheit Sturdevant et al.   PLoS Pathogens

Neurovirological Correlation With HIV-Associated Neurocognitive Disorders and Encephalitis in a HAART-Era Cohort

(2012) Benjamin B. Gelman et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Central Nervous System Viral Invasion and Inflammation During Acute HIV Infection

(2012) Victor Valcour et al.   JOURNAL OF INFECTIOUS DISEASES

Programming of neurotoxic cofactor CXCL-10 in HIV-1-associated dementia: abrogation of CXCL-10-induced neuro-glial toxicity in vitro by PKC activator

(2012) Rajeev Mehla et al.   Journal of Neuroinflammation

Impact of Multi-Targeted Antiretroviral Treatment on Gut T Cell Depletion and HIV Reservoir Seeding during Acute HIV Infection

(2012) Jintanat Ananworanich et al.   PLoS One

Immediate antiviral therapy appears to restrict resting CD4+ cell HIV-1 infection without accelerating the decay of latent infection

(2012) N. M. Archin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brain Cell Reservoirs of Latent Virus in Presymptomatic HIV-Infected Individuals

(2011) Katherine A. Thompson et al.   AMERICAN JOURNAL OF PATHOLOGY

HIV-1 Utilizes the CXCR4 Chemokine Receptor to Infect Multipotent Hematopoietic Stem and Progenitor Cells

(2011) Christoph C. Carter et al.   Cell Host & Microbe

Effect of antiretroviral therapy on HIV-1 genetic evolution during acute infection

(2011) A Chamberland et al.   INTERNATIONAL JOURNAL OF STD & AIDS

Central Nervous System Immune Activation Characterizes Primary Human Immunodeficiency Virus 1 Infection Even in Participants With Minimal Cerebrospinal Fluid Viral Burden

(2011) Serena Spudich et al.   JOURNAL OF INFECTIOUS DISEASES

Detection of Minority Resistance during Early HIV-1 Infection: Natural Variation and Spurious Detection rather than Transmission and Evolution of Multiple Viral Variants

(2011) S. Gianella et al.   JOURNAL OF VIROLOGY

The Gut Mucosal Viral Reservoir in HIV-Infected Patients Is Not the Major Source of Rebound Plasma Viremia following Interruption of Highly Active Antiretroviral Therapy

(2011) P. Lerner et al.   JOURNAL OF VIROLOGY

HIV-1 Replication in the Central Nervous System Occurs in Two Distinct Cell Types

(2011) Gretja Schnell et al.   PLoS Pathogens

Datamonkey 2010: a suite of phylogenetic analysis tools for evolutionary biology

(2010) W. Delport et al.   BIOINFORMATICS

HIV DNA in circulating monocytes as a mechanism to dementia and other HIV complications

(2010) Victor G. Valcour et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Response to Comment on "The Origins of Sexually Transmitted HIV Among Men Who Have Sex with Men"

(2010) D. Smith et al.   Science Translational Medicine

Hematopoietic stem/precursor cells as HIV reservoirs

(2010) Lucy A McNamara et al.   Current Opinion in HIV and AIDS

Cross-sectional characterization of HIV-1 env compartmentalization in cerebrospinal fluid over the full disease course

(2009) Patrick R Harrington et al.   AIDS

Compartmentalization and Clonal Amplification of HIV-1 Variants in the Cerebrospinal Fluid during Primary Infection

(2009) G. Schnell et al.   JOURNAL OF VIROLOGY

Evidence for Limited Genetic Compartmentalization of HIV-1 between Lung and Blood

(2009) Laura Heath et al.   PLoS One

Compartmentalized Human Immunodeficiency Virus Type 1 Originates from Long-Lived Cells in Some Subjects with HIV-1–Associated Dementia

(2009) Gretja Schnell et al.   PLoS Pathogens

Validation of the CNS Penetration-Effectiveness Rank for Quantifying Antiretroviral Penetration Into the Central Nervous System

(2008) Scott Letendre   ARCHIVES OF NEUROLOGY

Persistence of Transmitted Drug Resistance among Subjects with Primary Human Immunodeficiency Virus Infection

(2008) S. J. Little et al.   JOURNAL OF VIROLOGY

Pleocytosis is associated with disruption of HIV compartmentalization between blood and cerebral spinal fluid viral populations

(2008) Davey M. Smith et al.   VIROLOGY