Naturally Acquired Human Immunity to Pneumococcus Is Dependent on Antibody to Protein Antigens

A dynamic relationship between mucosal T helper type 17 and regulatory T-cell populations in nasopharynx evolves with age and associates with the clearance of pneumococcal carriage in humans

(2016) A. Mubarak et al.   CLINICAL MICROBIOLOGY AND INFECTION

Pneumococcal Capsules and Their Types: Past, Present, and Future

(2015) K. Aaron Geno et al.   CLINICAL MICROBIOLOGY REVIEWS

Importance of Bacterial Replication and Alveolar Macrophage-Independent Clearance Mechanisms during Early Lung Infection with Streptococcus pneumoniae

(2015) Emilie Camberlein et al.   INFECTION AND IMMUNITY

Regulation of Neutrophilic Inflammation by Proteinase-Activated Receptor 1 during Bacterial Pulmonary Infection

(2015) Ricardo J. José et al.   JOURNAL OF IMMUNOLOGY

Identification of the Streptococcus pyogenes surface antigens recognised by pooled human immunoglobulin

(2015) Mark Reglinski et al.   Scientific Reports

Protective Role of the Capsule and Impact of Serotype 4 Switching on Streptococcus mitis

(2014) Håkon V. Rukke et al.   INFECTION AND IMMUNITY

Antibody blocks acquisition of bacterial colonization through agglutination

(2014) A M Roche et al.   Mucosal Immunology

The Role of Host and Microbial Factors in the Pathogenesis of Pneumococcal Bacteraemia Arising from a Single Bacterial Cell Bottleneck

(2014) Alice Gerlini et al.   PLoS Pathogens

Controlled Human Infection and Rechallenge withStreptococcus pneumoniaeReveals the Protective Efficacy of Carriage in Healthy Adults

(2013) Daniela M. Ferreira et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Serum antibody responses to pneumococcal colonization in the first 2 years of life: results from an SE Asian longitudinal cohort study

(2013) P. Turner et al.   CLINICAL MICROBIOLOGY AND INFECTION

Experimental Human Pneumococcal Carriage Augments IL-17A-dependent T-cell Defence of the Lung

(2013) Adam K. A. Wright et al.   PLoS Pathogens

Nasopharyngeal Colonization Elicits Antibody Responses to Staphylococcal and Pneumococcal Proteins That Are Not Associated with a Reduced Risk of Subsequent Carriage

(2012) Sabine M. P. J. Prevaes et al.   INFECTION AND IMMUNITY

Reduced Serum IgG Responses to Pneumococcal Antigens in Otitis-Prone Children May Be Due to Poor Memory B-Cell Generation

(2012) Sharad K. Sharma et al.   JOURNAL OF INFECTIOUS DISEASES

P4-Mediated Antibody Therapy in an Acute Model of Invasive Pneumococcal Disease

(2012) Mathieu Bangert et al.   JOURNAL OF INFECTIOUS DISEASES

Effects of Deletion of the Streptococcus pneumoniae Lipoprotein Diacylglyceryl Transferase Gene lgt on ABC Transporter Function and on Growth In Vivo

(2012) Suneeta Chimalapati et al.   PLoS One

Contributions of capsule, lipoproteins and duration of colonisation towards the protective immunity of prior Streptococcus pneumoniae nasopharyngeal colonisation

(2012) Jonathan M. Cohen et al.   VACCINE

Biochemical Characterization of the Histidine Triad Protein PhtD as a Cell Surface Zinc-Binding Protein of Pneumococcus

(2011) Elodie Loisel et al.   BIOCHEMISTRY

TH17-Based Vaccine Design for Prevention of Streptococcus pneumoniae Colonization

(2011) Kristin L. Moffitt et al.   Cell Host & Microbe

Comparison of a New Multiplex Binding Assay versus the Enzyme-Linked Immunosorbent Assay for Measurement of Serotype-Specific Pneumococcal Capsular Polysaccharide IgG

(2011) David Goldblatt et al.   Clinical and Vaccine Immunology

Infection with Conditionally Virulent Streptococcus pneumoniae ΔpabStrains Induces Antibody to Conserved Protein Antigens but Does Not Protect against Systemic Infection with Heterologous Strains

(2011) Suneeta Chimalapati et al.   INFECTION AND IMMUNITY

Natural Antibodies against Several Pneumococcal Virulence Proteins in Children during the Pre-Pneumococcal-Vaccine Era: the Generation R Study

(2011) Ankie Lebon et al.   INFECTION AND IMMUNITY

Effectiveness of Immunoglobulin Replacement Therapy on Clinical Outcome in Patients with Primary Antibody Deficiencies: Results from a Multicenter Prospective Cohort Study

(2011) Isabella Quinti et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Serum Antibody Response to Five Streptococcus pneumoniae Proteins During Acute Otitis Media in Otitis-prone and Non–otitis-prone Children

(2011) Ravinder Kaur et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Protective Contributions against Invasive Streptococcus pneumoniae Pneumonia of Antibody and Th17-Cell Responses to Nasopharyngeal Colonisation

(2011) Jonathan M. Cohen et al.   PLoS One

Natural immune boosting in pertussis dynamics and the potential for long-term vaccine failure

(2011) J. S. Lavine et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of the Targets of Cross-Reactive Antibodies Induced by Streptococcus pneumoniae Colonization

(2010) A. M. Roche et al.   INFECTION AND IMMUNITY

The immunising effect of pneumococcal nasopharyngeal colonisation; protection against future colonisation and fatal invasive disease

(2009) Luke Richards et al.   IMMUNOBIOLOGY

Streptococcus pneumoniae Resistance to Complement-Mediated Immunity Is Dependent on the Capsular Serotype

(2009) C. Hyams et al.   INFECTION AND IMMUNITY

The Streptococcus pneumoniae Capsule Inhibits Complement Activity and Neutrophil Phagocytosis by Multiple Mechanisms

(2009) C. Hyams et al.   INFECTION AND IMMUNITY

T Cell Memory Response to Pneumococcal Protein Antigens in an Area of High Pneumococcal Carriage and Disease

(2009) Marianne W. Mureithi et al.   JOURNAL OF INFECTIOUS DISEASES

Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates

(2009) Katherine L O'Brien et al.   LANCET

Maturation ofStreptococcus pneumoniaelipoproteins by a type II signal peptidase is required for ABC transporter function and full virulence

(2009) Suneeta Khandavilli et al.   MOLECULAR MICROBIOLOGY

Effects of Ageing and Gender on Naturally Acquired Antibodies to Pneumococcal Capsular Polysaccharides and Virulence-Associated Proteins

(2008) B. Simell et al.   Clinical and Vaccine Immunology

Impaired Opsonization with C3b and Phagocytosis of Streptococcus pneumoniae in Sera from Subjects with Defects in the Classical Complement Pathway

(2008) J. Yuste et al.   INFECTION AND IMMUNITY

Epidemiologic Evidence for Serotype‐Specific Acquired Immunity to Pneumococcal Carriage

(2008) Daniel M. Weinberger et al.   JOURNAL OF INFECTIOUS DISEASES