Prions amplify through degradation of the VPS10P sorting receptor sortilin

Sorting receptor sortilin—a culprit in cardiovascular and neurological diseases

(2014) Anne-Sophie Carlo et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Mouse-Hamster Chimeric Prion Protein (PrP) Devoid of N-Terminal Residues 23-88 Restores Susceptibility to 22L Prions, but Not to RML Prions in PrP-Knockout Mice

(2014) Keiji Uchiyama et al.   PLoS One

Lysosomal Sorting of Amyloid-  by the SORLA Receptor Is Impaired by a Familial Alzheimer's Disease Mutation

(2014) S. Caglayan et al.   Science Translational Medicine

Alternative fates of newly formed PrPSc upon prion conversion on the plasma membrane

(2013) R. Goold et al.   JOURNAL OF CELL SCIENCE

Amyloid beta1-42(Aβ42) up-regulates the expression of sortilin via the p75NTR/RhoA signaling pathway

(2013) Khalil Saadipour et al.   JOURNAL OF NEUROCHEMISTRY

Prions disturb post-Golgi trafficking of membrane proteins

(2013) Keiji Uchiyama et al.   Nature Communications

Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP)

(2013) C Reitz et al.   Translational Psychiatry

Prion-infected cells regulate the release of exosomes with distinct ultrastructural features

(2012) Bradley M. Coleman et al.   FASEB JOURNAL

Biological and Biochemical Characterization of Mice Expressing Prion Protein Devoid of the Octapeptide Repeat Region after Infection with Prions

(2012) Yoshitaka Yamaguchi et al.   PLoS One

α-Cleavage of cellular prion protein

(2012) Jingjing Liang et al.   Prion

Sortilin: a receptor to regulate neuronal viability and function

(2012) Anders Nykjaer et al.   TRENDS IN NEUROSCIENCES

Meta-analysis of the Association Between Variants in SORL1 and Alzheimer Disease

(2011) Christiane Reitz   ARCHIVES OF NEUROLOGY

BACE1 Retrograde Trafficking Is Uniquely Regulated by the Cytoplasmic Domain of Sortilin

(2011) Gina M. Finan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of intracellular localization of PrPSc in prion-infected cells using a mAb that recognizes the region consisting of aa 119-127 of mouse PrP

(2011) T. Yamasaki et al.   JOURNAL OF GENERAL VIROLOGY

Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling

(2010) Christian B Vaegter et al.   NATURE NEUROSCIENCE

Sortilin-Mediated Endocytosis Determines Levels of the Frontotemporal Dementia Protein, Progranulin

(2010) Fenghua Hu et al.   NEURON

Preservation of cortical sortilin protein levels in MCI and Alzheimer's disease

(2010) Elliott J. Mufson et al.   NEUROSCIENCE LETTERS

The Vps10p-domain receptor family

(2009) Guido Hermey   CELLULAR AND MOLECULAR LIFE SCIENCES

Ligands bind to Sortilin in the tunnel of a ten-bladed β-propeller domain

(2009) Esben M Quistgaard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Immunolocalisation of PrPSc in scrapie-infected N2a mouse neuroblastoma cells by light and electron microscopy

(2008) Nathalie M. Veith et al.   EUROPEAN JOURNAL OF CELL BIOLOGY