Fatty acid DSF binds and allosterically activates histidine kinase RpfC of phytopathogenic bacterium Xanthomonas campestris pv. campestris to regulate quorum-sensing and virulence

Diffusible signal factor family signals provide a fitness advantage to Xanthomonas campestris pv. campestris in interspecies competition

(2016) Yinyue Deng et al.   ENVIRONMENTAL MICROBIOLOGY

Identification and characterization of naturally occurring DSF-family quorum sensing signal turnover system in the phytopathogenXanthomonas

(2015) Lian Zhou et al.   ENVIRONMENTAL MICROBIOLOGY

Xanthomonas campestriscell–cell signalling molecule DSF (diffusible signal factor) elicits innate immunity in plants and is suppressed by the exopolysaccharide xanthan

(2015) Akanksha Kakkar et al.   JOURNAL OF EXPERIMENTAL BOTANY

Activation of the bacterial thermosensor DesK involves a serine zipper dimerization motif that is modulated by bilayer thickness

(2015) Larisa Estefanía Cybulski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The DSF Family of Cell–Cell Signals: An Expanding Class of Bacterial Virulence Regulators

(2015) Robert P. Ryan et al.   PLoS Pathogens

Genome-Wide Identification of Genes Necessary for Biofilm Formation by Nosocomial Pathogen Stenotrophomonas maltophilia Reveals that Orphan Response Regulator FsnR Is a Critical Modulator

(2014) Xiu-Min Kang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Activation and Inhibition of the Receptor Histidine Kinase AgrC Occurs through Opposite Helical Transduction Motions

(2014) Boyuan Wang et al.   MOLECULAR CELL

The PAS domain-containing histidine kinase RpfS is a second sensor for the diffusible signal factor ofXanthomonas campestris

(2014) Shi-Qi An et al.   MOLECULAR MICROBIOLOGY

High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875

(2014) Ankita Srivastava et al.   NATURE

Piston versus Scissors: Chemotaxis Receptors versus Sensor His-Kinase Receptors in Two-Component Signaling Pathways

(2014) Joseph J. Falke   STRUCTURE

Cis-2-dodecenoic acid quorum sensing system modulates N-acyl homoserine lactone production through RpfR and cyclic di-GMP turnover in Burkholderia cenocepacia

(2013) Yinyue Deng et al.   BMC MICROBIOLOGY

The Therapeutic Potential of Allosteric Ligands for Free Fatty Acid Sensitive GPCRs

(2013) Brian D. Hudson et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

A three-component signalling system fine-tunes expression kinetics of HPPK responsible for folate synthesis by positive feedback loop during stress response ofXanthomonas campestris

(2013) Fang-Fang Wang et al.   ENVIRONMENTAL MICROBIOLOGY

Diffusible Signal Factor (DSF) Synthase RpfF of Xylella fastidiosa Is a Multifunction Protein Also Required for Response to DSF

(2013) M. Ionescu et al.   JOURNAL OF BACTERIOLOGY

Genetic and Proteomic Analyses of a Xanthomonas campestris pv. campestris purC Mutant Deficient in Purine Biosynthesis and Virulence

(2013) Zhihui Yuan et al.   Journal of Genetics and Genomics

Bacterial Quorum Sensing: Its Role in Virulence and Possibilities for Its Control

(2013) S. T. Rutherford et al.   Cold Spring Harbor Perspectives in Medicine

Microscale thermophoresis quantifies biomolecular interactions under previously challenging conditions

(2012) Susanne A.I. Seidel et al.   METHODS

A scissor blade-like closing mechanism implicated in transmembrane signaling in a Bacteroides hybrid two-component system

(2012) E. C. Lowe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cis-2-dodecenoic acid receptor RpfR links quorum-sensing signal perception with regulation of virulence through cyclic dimeric guanosine monophosphate turnover

(2012) Y. Deng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of human EGF receptor by lipids

(2011) U. Coskun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drug–protein binding: a critical review of analytical tools

(2010) Karine Vuignier et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Bacterial Sensor Kinases: Diversity in the Recognition of Environmental Signals

(2010) Tino Krell et al.   Annual Review of Microbiology

Rice bacterial blight pathogen Xanthomonas oryzae pv. oryzae produces multiple DSF-family signals in regulation of virulence factor production

(2010) Ya-Wen He et al.   BMC MICROBIOLOGY

Listening to a New Language: DSF-Based Quorum Sensing in Gram-Negative Bacteria

(2010) Yinyue Deng et al.   CHEMICAL REVIEWS

Sensor domains of two-component regulatory systems

(2010) Jonah Cheung et al.   CURRENT OPINION IN MICROBIOLOGY

Summary of useful methods for two-component system research

(2010) Birgit E Scharf   CURRENT OPINION IN MICROBIOLOGY

Probing bacterial transmembrane histidine kinase receptor-ligand interactions with natural and synthetic molecules

(2010) W.-L. Ng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis of the Sensor-Synthase Interaction in Autoinduction of the Quorum Sensing Signal DSF Biosynthesis

(2010) Zhihong Cheng et al.   STRUCTURE

Protein-binding assays in biological liquids using microscale thermophoresis

(2010) Christoph J. Wienken et al.   Nature Communications

Bacterial Quorum-Sensing Network Architectures

(2009) Wai-Leung Ng et al.   Annual Review of Genetics

Biophysical techniques for ligand screening and drug design

(2009) Jean-Paul Renaud et al.   CURRENT OPINION IN PHARMACOLOGY

The Cyclic Nucleotide Monophosphate Domain of Xanthomonas campestris Global Regulator Clp Defines a New Class of Cyclic Di-GMP Effectors

(2009) F. Tao et al.   JOURNAL OF BACTERIOLOGY

Structural Analysis of Ligand Stimulation of the Histidine Kinase NarX

(2009) Jonah Cheung et al.   STRUCTURE

Genome-Scale Mutagenesis and Phenotypic Characterization of Two-Component Signal Transduction Systems in Xanthomonas campestris pv. campestris ATCC 33913

(2008) Wei Qian et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Two-Component Signal Transduction Systems ofXanthomonasspp.: A Lesson from Genomics

(2008) Wei Qian et al.   MOLECULAR PLANT-MICROBE INTERACTIONS