LigB subunit vaccine confers sterile immunity against challenge in the hamster model of leptospirosis

Plasmin cleaves fibrinogen and the human complement proteins C3b and C5 in the presence of Leptospira interrogans proteins: A new role of LigA and LigB in invasion and complement immune evasion

(2016) Mónica Marcela Castiblanco-Valencia et al.   IMMUNOBIOLOGY

What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira

(2016) Derrick E. Fouts et al.   PLoS Neglected Tropical Diseases

Waterborne Leptospirosis: Survival and Preservation of the Virulence of Pathogenic Leptospira spp. in Fresh Water

(2015) Genevieve Andre-Fontaine et al.   CURRENT MICROBIOLOGY

Advances in aluminum hydroxide-based adjuvant research and its mechanism

(2015) Peng He et al.   Human Vaccines & Immunotherapeutics

Fine Mapping of the Interaction between C4b-Binding Protein and Outer Membrane Proteins LigA and LigB of Pathogenic Leptospira interrogans

(2015) Leandro C. D. Breda et al.   PLoS Neglected Tropical Diseases

Global Morbidity and Mortality of Leptospirosis: A Systematic Review

(2015) Federico Costa et al.   PLoS Neglected Tropical Diseases

Molecular Detection of Leptospiral DNA in Environmental Water on St. Kitts

(2014) Julienne Rawlins et al.   International Journal of Environmental Research and Public Health

Xanthan Gum as an Adjuvant in a Subunit Vaccine Preparation against Leptospirosis

(2014) Katia L. Bacelo et al.   Biomed Research International

USDA regulatory guidelines and practices for veterinary Leptospira vaccine potency testing

(2013) G.B. Srinivas et al.   BIOLOGICALS

Oral Immunization with Escherichia coli Expressing a Lipidated Form of LigA Protects Hamsters against Challenge with Leptospira interrogans Serovar Copenhageni

(2013) Kristel Lourdault et al.   INFECTION AND IMMUNITY

Adaptation of a real-time PCR method for the detection and quantification of pathogenic leptospires in environmental water

(2012) Julie Vein et al.   CANADIAN JOURNAL OF MICROBIOLOGY

Leptospiral Immunoglobulin-like Proteins Interact With Human Complement Regulators Factor H, FHL-1, FHR-1, and C4BP

(2012) Mónica Marcela Castiblanco-Valencia et al.   JOURNAL OF INFECTIOUS DISEASES

Quantitative PCR-based detection of pathogenic Leptospira in Hawai'ian coastal streams

(2012) Emily J. Viau et al.   JOURNAL OF WATER AND HEALTH

Detection and Quantification of Leptospira interrogans in Hamster and Rat Kidney Samples: Immunofluorescent Imprints versus Real-time PCR

(2012) Adenizar D. Chagas-Junior et al.   PLoS One

Multiple Activities of LigB Potentiate Virulence of Leptospira interrogans: Inhibition of Alternative and Classical Pathways of Complement

(2012) Henry A. Choy   PLoS One

Evaluation of 238 antigens of Leptospira borgpetersenii serovar Hardjo for protection against kidney colonisation

(2012) Gerald L. Murray et al.   VACCINE

Heterologous expression of pathogen-specific genes ligA and ligB in the saprophyte Leptospira biflexa confers enhanced adhesion to cultured cells and fibronectin

(2011) Cláudio Figueira et al.   BMC MICROBIOLOGY

Recombinant vaccines against Leptospirosis

(2011) Odir A. Dellagostin et al.   Human vaccines & immunotherapeutics

Attenuated Nephritis in Inducible Nitric Oxide Synthase Knockout C57BL/6 Mice and Pulmonary Hemorrhage in CB17 SCID and Recombination Activating Gene 1 Knockout C57BL/6 Mice Infected with Leptospira interrogans

(2011) Maurício Bandeira et al.   INFECTION AND IMMUNITY

The Multifunctional LigB Adhesin Binds Homeostatic Proteins with Potential Roles in Cutaneous Infection by Pathogenic Leptospira interrogans

(2011) Henry A. Choy et al.   PLoS One

A LigA Three-Domain Region Protects Hamsters from Lethal Infection by Leptospira interrogans

(2011) Mariana L. Coutinho et al.   PLoS Neglected Tropical Diseases

The C-terminal variable domain of LigB fromLeptospiramediates binding to fibronectin

(2010) Yi-Pin Lin et al.   Journal of Veterinary Science

Bioinformatics Describes Novel Loci for High Resolution Discrimination of Leptospira Isolates

(2010) Gustavo M. Cerqueira et al.   PLoS One

An imprint method for detecting leptospires in the hamster model of vaccine-mediated immunity for leptospirosis

(2009) A. D. Chagas-Junior et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Distribution of the leptospiral immunoglobulin-like (lig) genes in pathogenic Leptospira species and application of ligB to typing leptospiral isolates

(2009) G. M. Cerqueira et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Leptospira and leptospirosis

(2009) Ben Adler et al.   VETERINARY MICROBIOLOGY

Genetic diversity of the Leptospiral immunoglobulin-like (Lig) genes in pathogenic Leptospira spp.

(2008) Alan J.A. McBride et al.   INFECTION GENETICS AND EVOLUTION

Immunogenicity and protective efficacy of recombinant Leptospira immunoglobulin-like protein B (rLigB) in a hamster challenge model

(2008) Weiwei Yan et al.   MICROBES AND INFECTION

Leptospira immunoglobulin-like protein A variable region (LigAvar) incorporated in liposomes and PLGA microspheres produces a robust immune response correlating to protective immunity

(2008) Syed M. Faisal et al.   VACCINE

Evaluation of protective immunity of Leptospira immunoglobulin like protein A (LigA) DNA vaccine against challenge in hamsters

(2007) Syed M. Faisal et al.   VACCINE