Safety and efficacy of a freeze-dried trivalent antivenom for snakebites in the Brazilian Amazon: An open randomized controlled phase IIb clinical trial
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Safety and efficacy of a freeze-dried trivalent antivenom for snakebites in the Brazilian Amazon: An open randomized controlled phase IIb clinical trial
Authors
Keywords
Snakebite, Brazil, Slavic people, Adverse events, Venoms, Fibrinogen, Adverse reactions, Creatine
Journal
PLoS Neglected Tropical Diseases
Volume 11, Issue 11, Pages e0006068
Publisher
Public Library of Science (PLoS)
Online
2017-11-28
DOI
10.1371/journal.pntd.0006068
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Thermal stabilization of anti-α-cobratoxin single domain antibodies
- (2017) George P. Anderson et al. TOXICON
- Physicochemical characterization of commercial freeze-dried snake antivenoms
- (2017) María Herrera et al. TOXICON
- Comparison of venoms from wild and long-term captive Bothrops atrox snakes and characterization of Batroxrhagin, the predominant class PIII metalloproteinase from the venom of this species
- (2015) L.A. Freitas-de-Sousa et al. BIOCHIMIE
- Snakebites as a largely neglected problem in the Brazilian Amazon: highlights of the epidemiological trends in the State of Amazonas
- (2015) Esaú Samuel Feitosa et al. Revista da Sociedade Brasileira de Medicina Tropical
- Snakebites and Scorpion Stings in the Brazilian Amazon: Identifying Research Priorities for a Largely Neglected Problem
- (2015) Fan Hui Wen et al. PLoS Neglected Tropical Diseases
- Older Age and Time to Medical Assistance Are Associated with Severity and Mortality of Snakebites in the Brazilian Amazon: A Case-Control Study
- (2015) Esaú L. Feitosa et al. PLoS One
- Freeze-dried snake antivenoms formulated with sorbitol, sucrose or mannitol: Comparison of their stability in an accelerated test
- (2014) María Herrera et al. TOXICON
- Validating a faster method for reconstitution of Crotalidae Polyvalent Immune Fab (ovine)
- (2013) David Gerring et al. TOXICON
- Comparison of Phylogeny, Venom Composition and Neutralization by Antivenom in Diverse Species of Bothrops Complex
- (2013) Leijiane F. Sousa et al. PLoS Neglected Tropical Diseases
- Effect of Pre-Medication on Early Adverse Reactions Following Antivenom Use in Snakebite
- (2011) Abdulrazaq G. Habib DRUG SAFETY
- Comparative study of the efficacy and safety of two polyvalent, caprylic acid fractionated [IgG and F(ab′)2] antivenoms, in Bothrops asper bites in Colombia
- (2011) Rafael Otero-Patiño et al. TOXICON
- Improving Crotalidae polyvalent immune Fab reconstitution times
- (2010) Asia N. Quan et al. AMERICAN JOURNAL OF EMERGENCY MEDICINE
- Systematic investigation of the effect of lyophilizate collapse on pharmaceutically relevant proteins I: Stability after freeze‐drying
- (2009) K. Schersch et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Epidemiological, clinical and therapeutic aspects of Bothrops asper bites
- (2009) Rafael Otero-Patiño TOXICON
- Stability of equine IgG antivenoms obtained by caprylic acid precipitation: Towards a liquid formulation stable at tropical room temperature
- (2009) Álvaro Segura et al. TOXICON
- The Global Burden of Snakebite: A Literature Analysis and Modelling Based on Regional Estimates of Envenoming and Deaths
- (2008) Anuradhani Kasturiratne et al. PLOS MEDICINE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started