Challenges in preparing and implementing a clinical trial at field level in an Ebola emergency: A case study in Guinea, West Africa

Conducting clinical trials in outbreak settings: Points to consider

(2016) H Clifford Lane et al.   Clinical Trials

Trial design for evaluating novel treatments during an outbreak of an infectious disease

(2016) John Whitehead et al.   Clinical Trials

Evaluation of Convalescent Plasma for Ebola Virus Disease in Guinea

(2016) Johan van Griensven et al.   NEW ENGLAND JOURNAL OF MEDICINE

Social and cultural factors behind community resistance during an Ebola outbreak in a village of the Guinean Forest region, February 2015: a field experience

(2016) A.I. Carrión Martín et al.   International Health

Experimental Treatment of Ebola Virus Disease with TKM-130803: A Single-Arm Phase 2 Clinical Trial

(2016) Jake Dunning et al.   PLOS MEDICINE

Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea

(2016) Daouda Sissoko et al.   PLOS MEDICINE

Experimental Treatment of Ebola Virus Disease with Brincidofovir

(2016) Jake Dunning et al.   PLoS One

Favipiravir for children with Ebola

(2015) Naïm Bouazza et al.   LANCET

Are adaptive randomised trials or non-randomised studies the best way to address the Ebola outbreak in west Africa?

(2015) Simone Lanini et al.   LANCET INFECTIOUS DISEASES

Ebola Virus Disease among Children in West Africa

(2015)   NEW ENGLAND JOURNAL OF MEDICINE

Ebola Virus Disease and Marburg Disease in Pregnancy

(2015) Lisa M. Bebell et al.   OBSTETRICS AND GYNECOLOGY

Ebola outbreak in rural West Africa: epidemiology, clinical features and outcomes

(2015) Silvia Dallatomasina et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model

(2014) Lisa Oestereich et al.   ANTIVIRAL RESEARCH

Evaluating Novel Therapies During the Ebola Epidemic

(2014) Steven Joffe   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Randomised controlled trials for Ebola: practical and ethical issues

(2014) Clement Adebamowo et al.   LANCET

Evaluating Ebola Therapies — The Case for RCTs

(2014) Edward Cox et al.   NEW ENGLAND JOURNAL OF MEDICINE

WHO gives go ahead for experimental treatments to be used in Ebola outbreak

(2014) A. Sayburn   BMJ-British Medical Journal

Favipiravir (T-705), a novel viral RNA polymerase inhibitor

(2013) Yousuke Furuta et al.   ANTIVIRAL RESEARCH

Favipiravir (T-705) Inhibits Junín Virus Infection and Reduces Mortality in a Guinea Pig Model of Argentine Hemorrhagic Fever

(2013) Brian B. Gowen et al.   PLoS Neglected Tropical Diseases

Effective Oral Favipiravir (T-705) Therapy Initiated after the Onset of Clinical Disease in a Model of Arenavirus Hemorrhagic Fever

(2011) Michelle Mendenhall et al.   PLoS Neglected Tropical Diseases