Post-Translational Dosage Compensation Buffers Genetic Perturbations to Stoichiometry of Protein Complexes

Aneuploid proliferation defects in yeast are not driven by copy number changes of a few dosage-sensitive genes

(2015) Megan E. Bonney et al.   GENES & DEVELOPMENT

Protein degradation corrects for imbalanced subunit stoichiometry in OST complex assembly

(2015) Susanne Mueller et al.   MOLECULAR BIOLOGY OF THE CELL

Operon structure and cotranslational subunit association direct protein assembly in bacteria

(2015) Y.-W. Shieh et al.   SCIENCE

Quantifying Absolute Protein Synthesis Rates Reveals Principles Underlying Allocation of Cellular Resources

(2014) Gene-Wei Li et al.   CELL

Aneuploidy: implications for protein homeostasis and disease

(2014) A. B. Oromendia et al.   Disease Models & Mechanisms

Targeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling

(2014) C. C. Williams et al.   SCIENCE

Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling

(2014) C. H. Jan et al.   SCIENCE

Quantitative proteomic analysis reveals posttranslational responses to aneuploidy in yeast

(2014) Noah Dephoure et al.   eLife

Dynamic karyotype, dynamic proteome: buffering the effects of aneuploidy

(2013) Neysan Donnelly et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Role of Saw1 in Rad1/Rad10 complex assembly at recombination intermediates in budding yeast

(2013) Fuyang Li et al.   EMBO JOURNAL

Aneuploid yeast strains exhibit defects in cell growth and passage through START

(2013) Rebecca R. Thorburn et al.   MOLECULAR BIOLOGY OF THE CELL

A Cotranslational Ubiquitination Pathway for Quality Control of Misfolded Proteins

(2013) Feng Wang et al.   MOLECULAR CELL

Control of Protein Quality and Stoichiometries by N-Terminal Acetylation and the N-End Rule Pathway

(2013) Anna Shemorry et al.   MOLECULAR CELL

Principles of Cotranslational Ubiquitination and Quality Control at the Ribosome

(2013) Stefanie Duttler et al.   MOLECULAR CELL

Relationships between Cell Cycle Regulator Gene Copy Numbers and Protein Expression Levels in Schizosaccharomyces pombe

(2013) Ayako Chino et al.   PLoS One

Identification of dosage-sensitive genes in Saccharomyces cerevisiae using the genetic tug-of-war method

(2012) K. Makanae et al.   GENOME RESEARCH

Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells

(2012) Silvia Stingele et al.   Molecular Systems Biology

The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments

(2012) Nicholas T Ingolia et al.   Nature Protocols

Rbg1–Tma46 dimer structure reveals new functional domains and their role in polysome recruitment

(2012) Sandrea M. Francis et al.   NUCLEIC ACIDS RESEARCH

Cellular Decision Making and Biological Noise: From Microbes to Mammals

(2011) Gábor Balázsi et al.   CELL

A Functional Interface at the rDNA Connects rRNA Synthesis, Pre-rRNA Processing and Nucleolar Surveillance in Budding Yeast

(2011) Nathalie Leporé et al.   PLoS One

Identification of Aneuploidy-Tolerating Mutations

(2010) Eduardo M. Torres et al.   CELL

A general lack of compensation for gene dosage in yeast

(2010) Michael Springer et al.   Molecular Systems Biology

Variability in gene expression underlies incomplete penetrance

(2010) Arjun Raj et al.   NATURE

Ohnologs in the human genome are dosage balanced and frequently associated with disease

(2010) T. Makino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fragilities Caused by Dosage Imbalance in Regulation of the Budding Yeast Cell Cycle

(2010) Kazunari Kaizu et al.   PLoS Genetics

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

Histone levels are regulated by phosphorylation and ubiquitylation-dependent proteolysis

(2009) Rakesh Kumar Singh et al.   NATURE CELL BIOLOGY

Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

(2009) N. T. Ingolia et al.   SCIENCE

Robustness: mechanisms and consequences

(2009) Joanna Masel et al.   TRENDS IN GENETICS

Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

(2008) Arjun Raj et al.   CELL

Aneuploidy: Cells Losing Their Balance

(2008) Eduardo M. Torres et al.   GENETICS