Bicaudal C mutation causes myc and TOR pathway up-regulation and polycystic kidney disease-like phenotypes in Drosophila

S6 Kinase is essential for MYC-dependent rDNA transcription in Drosophila

(2015) Naomi C. Mitchell et al.   CELLULAR SIGNALLING

Translational research in ADPKD: lessons from animal models

(2014) Hester Happé et al.   Nature Reviews Nephrology

Loss of Polycystin-1 Inhibits Bicc1 Expression during Mouse Development

(2014) Peiwen Lian et al.   PLoS One

The ever-evolving role of mTOR in translation

(2014) Bruno D. Fonseca et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Progressive development of polycystic kidney disease in the mouse model expressing Pkd1 extracellular domain

(2013) Almira Kurbegovic et al.   HUMAN MOLECULAR GENETICS

The Bic-C Family of Developmental Translational Regulators

(2012) Chiara Gamberi et al.   COMPARATIVE AND FUNCTIONAL GENOMICS

Two mutations in human BICC1 resulting in Wnt pathway hyperactivity associated with cystic renal dysplasia

(2011) Marine R.-C. Kraus et al.   HUMAN MUTATION

mTOR signaling in polycystic kidney disease

(2011) Oxana Ibraghimov-Beskrovnaya et al.   TRENDS IN MOLECULAR MEDICINE

Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster

(2010) Ivana Bjedov et al.   Cell Metabolism

Prospects for mTOR Inhibitor Use in Patients with Polycystic Kidney Disease and Hamartomatous Diseases

(2010) V. E. Torres et al.   Clinical Journal of the American Society of Nephrology

The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity

(2010) U. Tran et al.   DEVELOPMENT

Pkd1 transgenic mice: adult model of polycystic kidney disease with extrarenal and renal phenotypes

(2010) Almira Kurbegovic et al.   HUMAN MOLECULAR GENETICS

Rapamycin Ameliorates PKD Resulting from Conditional Inactivation of Pkd1

(2010) J. M. Shillingford et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The mTOR Pathway Is Activated in Human Autosomal-Recessive Polycystic Kidney Disease

(2010) Jan Ulrich Becker et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Nephronophthisis

(2010) Matthias T. F. Wolf et al.   PEDIATRIC NEPHROLOGY

Cystic kidney disease: the role of Wnt signaling

(2010) Madeline A. Lancaster et al.   TRENDS IN MOLECULAR MEDICINE

Dissecting the role of mTOR: Lessons from mTOR inhibitors

(2009) Ryan J.O. Dowling et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Bicaudal C, a novel regulator of Dvl signaling abutting RNA-processing bodies, controls cilia orientation and leftward flow

(2009) C. Maisonneuve et al.   DEVELOPMENT

A Drosophila Resource of Transgenic RNAi Lines for Neurogenetics

(2009) Jian-Quan Ni et al.   GENETICS

Defects in cell polarity underlie TSC and ADPKD-associated cystogenesis

(2009) Cleo S. Bonnet et al.   HUMAN MOLECULAR GENETICS

Systems biology of autosomal dominant polycystic kidney disease (ADPKD): computational identification of gene expression pathways and integrated regulatory networks

(2009) Xuewen Song et al.   HUMAN MOLECULAR GENETICS

Late progression of renal pathology and cyst enlargement is reduced by rapamycin in a mouse model of nephronophthisis

(2009) Vincent H. Gattone et al.   KIDNEY INTERNATIONAL

Polycystin-1 Regulates Extracellular Signal-Regulated Kinase-Dependent Phosphorylation of Tuberin To Control Cell Size through mTOR and Its Downstream Effectors S6K and 4EBP1

(2009) G. Distefano et al.   MOLECULAR AND CELLULAR BIOLOGY

Activation of the AKT/mTOR pathway in autosomal recessive polycystic kidney disease (ARPKD)

(2009) D.-C. Fischer et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Polycystic Kidney Disease

(2008) Peter C. Harris et al.   Annual Review of Medicine

The tuberous sclerosis proteins regulate formation of the primary cilium via a rapamycin-insensitive and polycystin 1-independent pathway

(2008) Tiffiney R. Hartman et al.   HUMAN MOLECULAR GENETICS

The insect nephrocyte is a podocyte-like cell with a filtration slit diaphragm

(2008) Helen Weavers et al.   NATURE