Lethality of mice bearing a knockout of the Ngly1-gene is partially rescued by the additional deletion of the Engase gene

The cytoplasmic peptide: N -glycanase (NGLY1) — Structure, expression and cellular functions

(2016) Tadashi Suzuki et al.   GENE

Prospective phenotyping of NGLY1-CDDG, the first congenital disorder of deglycosylation

(2016) Christina Lam et al.   GENETICS IN MEDICINE

Non-lysosomal Degradation of Singly Phosphorylated Oligosaccharides Initiated by the Action of a Cytosolic Endo-β-N-acetylglucosaminidase

(2016) Yoichiro Harada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Catabolism of N-glycoproteins in mammalian cells: Molecular mechanisms and genetic disorders related to the processes

(2016) Tadashi Suzuki   MOLECULAR ASPECTS OF MEDICINE

Multi-systemic involvement in NGLY1-related disorder caused by two novel mutations

(2015) Jennifer Heeley et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Generation and degradation of free asparagine-linked glycans

(2015) Yoichiro Harada et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

NGLY1 mutation causes neuromotor impairment, intellectual disability, and neuropathy

(2015) Ahmet Okay Caglayan et al.   European Journal of Medical Genetics

Cytosolic-free oligosaccharides are predominantly generated by the degradation of dolichol-linked oligosaccharides in mammalian cells

(2015) Yoichiro Harada et al.   GLYCOBIOLOGY

Endo-β-N-acetylglucosaminidase formsN-GlcNAc protein aggregates during ER-associated degradation in Ngly1-defective cells

(2015) Chengcheng Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Non-lysosomal degradation pathway for N-linked glycans and dolichol-linked oligosaccharides

(2014) Tadashi Suzuki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mutations in NGLY1 cause an inherited disorder of the endoplasmic reticulum–associated degradation pathway

(2014) Gregory M. Enns et al.   GENETICS IN MEDICINE

The cytoplasmic peptide:N-glycanase (Ngly1)--basic science encounters a human genetic disorder

(2014) T. Suzuki   JOURNAL OF BIOCHEMISTRY

Selective glycopeptide profiling by acetone enrichment and LC/MS

(2014) Daisuke Takakura et al.   Journal of Proteomics

How early studies on secreted and membrane protein quality control gave rise to the ER associated degradation (ERAD) pathway: The early history of ERAD

(2013) Patrick G. Needham et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Overdosage of Hand2 causes limb and heart defects in the human chromosomal disorder partial trisomy distal 4q

(2013) Masaru Tamura et al.   HUMAN MOLECULAR GENETICS

N- andO-Glycosylation in the Murine Synaptosome

(2013) Jonathan C. Trinidad et al.   MOLECULAR & CELLULAR PROTEOMICS

Specificity and Regulation of the Endoplasmic Reticulum-Associated Degradation Machinery

(2013) Jessica Merulla et al.   TRAFFIC

A plant peptide: N-glycanase orthologue facilitates glycoprotein ER-associated degradation in yeast

(2012) Yuki Masahara-Negishi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Identification and characterization of peptide: N- glycanase from Dictyostelium discoideum

(2012) Anuradha Gosain et al.   BMC BIOCHEMISTRY

Clinical application of exome sequencing in undiagnosed genetic conditions

(2012) Anna C Need et al.   JOURNAL OF MEDICAL GENETICS

Identification and Origin of N-Linked  -D-N-Acetylglucosamine Monosaccharide Modifications on Arabidopsis Proteins

(2012) Y.-C. Kim et al.   PLANT PHYSIOLOGY

α1,6-Fucosyltransferase-deficient Mice Exhibit Multiple Behavioral Abnormalities Associated with a Schizophrenia-like Phenotype

(2011) Tomohiko Fukuda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The two endo-β-N-acetylglucosaminidase genes from Arabidopsis thaliana encode cytoplasmic enzymes controlling free N-glycan levels

(2011) Richard M. Fischl et al.   PLANT MOLECULAR BIOLOGY

Protein Native-State Stabilization by Placing Aromatic Side Chains in N-Glycosylated Reverse Turns

(2011) E. K. Culyba et al.   SCIENCE

Identification of an Htm1 (EDEM)-dependent, Mns1-independent Endoplasmic Reticulum-associated Degradation (ERAD) Pathway inSaccharomyces cerevisiae

(2010) Akira Hosomi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The N-Glycanase png-1 Acts to Limit Axon Branching during Organ Formation in Caenorhabditis elegans

(2010) N. Habibi-Babadi et al.   JOURNAL OF NEUROSCIENCE

Evidence for an Essential Deglycosylation-Independent Activity of PNGase in Drosophila melanogaster

(2010) Yoko Funakoshi et al.   PLoS One

TheNeurosporaPeptide:N-Glycanase Ortholog PNG1 Is Essential for Cell Polarity despite Its Lack of Enzymatic Activity

(2009) Sabine Maerz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histology Atlas of the Developing Mouse Heart with Emphasis on E11.5 to E18.5

(2009) Saija M. Savolainen et al.   TOXICOLOGIC PATHOLOGY

Synthesis and inhibitory activity of oligosaccharide thiazolines as a class of mechanism-based inhibitors for endo-β-N-acetylglucosaminidases

(2008) Bing Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY