Dysregulation of INF2-mediated mitochondrial fission in SPOP-mutated prostate cancer

Regulators of mitochondrial dynamics in cancer

(2016) Daniela Senft et al.   CURRENT OPINION IN CELL BIOLOGY

The Molecular Taxonomy of Primary Prostate Cancer

(2015) Adam Abeshouse et al.   CELL

Truncated ERG Oncoproteins from TMPRSS2-ERG Fusions Are Resistant to SPOP-Mediated Proteasome Degradation

(2015) Jian An et al.   MOLECULAR CELL

SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression

(2015) Wenjian Gan et al.   MOLECULAR CELL

Mitochondrial Division Is Requisite to RAS-Induced Transformation and Targeted by Oncogenic MAPK Pathway Inhibitors

(2015) Madhavika N. Serasinghe et al.   MOLECULAR CELL

Erk2 Phosphorylation of Drp1 Promotes Mitochondrial Fission and MAPK-Driven Tumor Growth

(2015) Jennifer A. Kashatus et al.   MOLECULAR CELL

Inverted formin 2 in focal adhesions promotes dorsal stress fiber and fibrillar adhesion formation to drive extracellular matrix assembly

(2015) Colleen T. Skau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SPOP E3 Ubiquitin Ligase Adaptor Promotes Cellular Senescence by Degrading the SENP7 deSUMOylase

(2015) Hengrui Zhu et al.   Cell Reports

Mitochondrial Dynamics Protein Drp1 Is Overexpressed in Oncocytic Thyroid Tumors and Regulates Cancer Cell Migration

(2015) André Ferreira-da-Silva et al.   PLoS One

SPOP Promotes Tumorigenesis by Acting as a Key Regulatory Hub in Kidney Cancer

(2014) Guoqiang Li et al.   CANCER CELL

Androgen Receptor Is the Key Transcriptional Mediator of the Tumor Suppressor SPOP in Prostate Cancer

(2014) C. Geng et al.   CANCER RESEARCH

Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer

(2014) J.-P. P. Theurillat et al.   SCIENCE

Destruction of Full-Length Androgen Receptor by Wild-Type SPOP, but Not Prostate-Cancer-Associated Mutants

(2014) Jian An et al.   Cell Reports

Mitochondrial Localization and the Persistent Migration of Epithelial Cancer cells

(2013) Salil P. Desai et al.   BIOPHYSICAL JOURNAL

MITOL Regulates Endoplasmic Reticulum-Mitochondria Contacts via Mitofusin2

(2013) Ayumu Sugiura et al.   MOLECULAR CELL

An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2

(2013) F. Korobova et al.   SCIENCE

Depletion of mitochondrial fission factor DRP1 causes increased apoptosis in human colon cancer cells

(2012) Akane Inoue-Yamauchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer

(2012) Jalees Rehman et al.   FASEB JOURNAL

The mutational landscape of lethal castration-resistant prostate cancer

(2012) Catherine S. Grasso et al.   NATURE

Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

(2012) Christopher E Barbieri et al.   NATURE GENETICS

Atypical ubiquitylation — the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages

(2012) Yogesh Kulathu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondrial dynamics regulates migration and invasion of breast cancer cells

(2012) J Zhao et al.   ONCOGENE

Adaptor Protein Self-Assembly Drives the Control of a Cullin-RING Ubiquitin Ligase

(2012) Wesley J. Errington et al.   STRUCTURE

Splice variant–specific cellular function of the formin INF2 in maintenance of Golgi architecture

(2011) Vinay Ramabhadran et al.   MOLECULAR BIOLOGY OF THE CELL

The genomic complexity of primary human prostate cancer

(2011) Michael F. Berger et al.   NATURE

INF2Mutations in Charcot–Marie–Tooth Disease with Glomerulopathy

(2011) Olivia Boyer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1

(2011) C Li et al.   ONCOGENE

Mitochondrial fusion and fission in cell life and death

(2010) Benedikt Westermann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Electron microscopy morphology of the mitochondrial network in human cancer

(2009) Gabriel Arismendi-Morillo   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

INF2 is an endoplasmic reticulum-associated formin protein

(2009) E. S. Chhabra et al.   JOURNAL OF CELL SCIENCE

Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases

(2009) Min Zhuang et al.   MOLECULAR CELL

Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis

(2009) Elizabeth J Brown et al.   NATURE GENETICS

Mitochondrial dynamics and cancer

(2008) Stéphanie Grandemange et al.   SEMINARS IN CANCER BIOLOGY