Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons

The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression

(2015) T. Hung et al.   SCIENCE

Impact ofOAS1Exon 7 rs10774671 Genetic Variation on Liver Fibrosis Progression in Egyptian HCV Genotype 4 Patients

(2015) Noha G. Bader El Din et al.   VIRAL IMMUNOLOGY

Prediction of Sjögren's Syndrome Years Before Diagnosis and Identification of Patients With Early Onset and Severe Disease Course by Autoantibody Profiling

(2015) Elke Theander et al.   Arthritis & Rheumatology

Mitochondrial localization of the OAS1 p46 isoform associated with a common single nucleotide polymorphism

(2014) Karina Kjær et al.   BMC CELL BIOLOGY

T cell epitope mimicry between Sjögren's syndrome Antigen A (SSA)/Ro60 and oral, gut, skin and vaginal bacteria

(2014) Agnieszka Szymula et al.   CLINICAL IMMUNOLOGY

Identifying Causal Variants at Loci with Multiple Signals of Association

(2014) F. Hormozdiari et al.   GENETICS

Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression

(2014) B. P. Fairfax et al.   SCIENCE

Correlation of OAS1 Gene Polymorphism at Exon 7 Splice Accepter Site with Interferon-Based Therapy of HCV Infection in Pakistan

(2014) Muhammad Imran et al.   VIRAL IMMUNOLOGY

A meta-analysis of gene expression quantitative trait loci in brain

(2014) Y Kim et al.   Translational Psychiatry

Comparison of the American-European Consensus Group Sjögren's syndrome classification criteria to newly proposed American College of Rheumatology criteria in a large, carefully characterised sicca cohort

(2013) Astrid Rasmussen et al.   ANNALS OF THE RHEUMATIC DISEASES

Autoimmunity and infection in Sjögrenʼs syndrome

(2013) Ann Igoe et al.   CURRENT OPINION IN RHEUMATOLOGY

Expression Quantitative Trait Loci Analysis Identifies Associations Between Genotype and Gene Expression in Human Intestine

(2013) Boyko Kabakchiev et al.   GASTROENTEROLOGY

A comprehensive review of autoantibodies in primary Sjögren's syndrome: Clinical phenotypes and regulatory mechanisms

(2013) Nikolaos C. Kyriakidis et al.   JOURNAL OF AUTOIMMUNITY

A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23

(2013) Yongzhe Li et al.   NATURE GENETICS

Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome

(2013) Christopher J Lessard et al.   NATURE GENETICS

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Systematic identification of trans eQTLs as putative drivers of known disease associations

(2013) Harm-Jan Westra et al.   NATURE GENETICS

Advances in understanding the pathogenesis of primary Sjögren's syndrome

(2013) Gaëtane Nocturne et al.   Nature Reviews Rheumatology

Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as Susceptibility Loci for Systemic Lupus Erythematosus in a Large-Scale Multiracial Replication Study

(2012) Christopher J. Lessard et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Matrix eQTL: ultra fast eQTL analysis via large matrix operations

(2012) A. A. Shabalin   BIOINFORMATICS

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

(2012) H. Thorvaldsdottir et al.   BRIEFINGS IN BIOINFORMATICS

Evaluate the relationship between polymorphisms of OAS1 gene and susceptibility to chronic hepatitis C with high resolution melting analysis

(2012) Yan Zhao et al.   CLINICAL AND EXPERIMENTAL MEDICINE

The interferon signature in autoimmune diseases

(2012) Lars Rönnblom et al.   CURRENT OPINION IN RHEUMATOLOGY

Differential effects of a common splice site polymorphism on the generation of OAS1 variants in human bronchial epithelial cells

(2012) Satoshi Noguchi et al.   HUMAN IMMUNOLOGY

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

TGF-β signaling to T cells inhibits autoimmunity during lymphopenia-driven proliferation

(2012) Nu Zhang et al.   NATURE IMMUNOLOGY

EBV reactivation serological profile in primary Sjögren’s syndrome: an underlying trigger of active articular involvement?

(2012) Sandra Gofinet Pasoto et al.   RHEUMATOLOGY INTERNATIONAL

Interferon type I signature may predict non response upon rituximab in rheumatoid arthritis patients

(2012) Hennie G Raterman et al.   ARTHRITIS RESEARCH & THERAPY

SS-A/Ro52 promotes apoptosis by regulating Bcl-2 production

(2011) Siti Nur Aisyah Jauharoh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of a new susceptibility variant for multiple sclerosis in OAS1 by population genetics analysis

(2011) Rachele Cagliani et al.   HUMAN GENETICS

The meaning of anti-Ro and anti-La antibodies in primary Sjögren's syndrome

(2010) Gabriela Hernández-Molina et al.   AUTOIMMUNITY REVIEWS

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

RNA sequencing reveals the role of splicing polymorphisms in regulating human gene expression

(2010) E. Lalonde et al.   GENOME RESEARCH

NF- B RelA Subunit Is Crucial for Early IFN-  Expression and Resistance to RNA Virus Replication

(2010) J. Wang et al.   JOURNAL OF IMMUNOLOGY

Understanding mechanisms underlying human gene expression variation with RNA sequencing

(2010) Joseph K. Pickrell et al.   NATURE

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

(2010) Eli A Stahl et al.   NATURE GENETICS

Pathogenetic mechanisms in the initiation and perpetuation of Sjögren's syndrome

(2010) Michael Voulgarelis et al.   Nature Reviews Rheumatology

OAS1: A multiple sclerosis susceptibility gene that influences disease severity

(2010) M. O'Brien et al.   NEUROLOGY

Critical role of IRF-5 in regulation of B-cell differentiation

(2010) C. Lien et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of IFN response gene activity during infliximab treatment in rheumatoid arthritis is associated with clinical response to treatment

(2010) Lisa GM van Baarsen et al.   ARTHRITIS RESEARCH & THERAPY

Type I interferon in organ-targeted autoimmune and inflammatory diseases

(2010) Mary K Crow   ARTHRITIS RESEARCH & THERAPY

The 1000 Genomes Project: new opportunities for research and social challenges

(2010) Marc Via et al.   Genome Medicine

A Bayesian Framework to Account for Complex Non-Genetic Factors in Gene Expression Levels Greatly Increases Power in eQTL Studies

(2010) Oliver Stegle et al.   PLoS Computational Biology

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

Lymphopenia-induced spontaneous T-cell proliferation as a cofactor for autoimmune disease development

(2009) A. Le Campion et al.   BLOOD

Type I interferon and lupus

(2009) Lars Rönnblom et al.   CURRENT OPINION IN RHEUMATOLOGY

Peripheral blood gene expression profiling in Sjögren's syndrome

(2009) E S Emamian et al.   GENES AND IMMUNITY

Gene expression and chromosomal location for susceptibility to Sjögren's syndrome

(2009) Paola Pérez et al.   JOURNAL OF AUTOIMMUNITY

A re-annotation pipeline for Illumina BeadArrays: improving the interpretation of gene expression data

(2009) Nuno L. Barbosa-Morais et al.   NUCLEIC ACIDS RESEARCH

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytokine and autoantibody profiling related to histopathological features in primary Sjogren's syndrome

(2009) T. R. Reksten et al.   RHEUMATOLOGY

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

Genetic Variation in OAS1 Is a Risk Factor for Initial Infection with West Nile Virus in Man

(2009) Jean K. Lim et al.   PLoS Pathogens

Prevalence, severity, and predictors of fatigue in subjects with primary Sjögren's syndrome

(2008) Barbara Segal et al.   ARTHRITIS AND RHEUMATISM

arrayQualityMetrics—a bioconductor package for quality assessment of microarray data

(2008) Audrey Kauffmann et al.   BIOINFORMATICS

Additive effects of the major risk alleles of IRF5 and STAT4 in primary Sjögren's syndrome

(2008) G Nordmark et al.   GENES AND IMMUNITY

A panel of ancestry informative markers for estimating individual biogeographical ancestry and admixture from four continents: utility and applications

(2008) Indrani Halder et al.   HUMAN MUTATION

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

(2008) John B Harley et al.   NATURE GENETICS