Structural host-microbiota interaction networks

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

(2016) Timothy R. Sampson et al.   CELL

Use of systems biology to decipher host–pathogen interaction networks and predict biomarkers

(2016) A. Dix et al.   CLINICAL MICROBIOLOGY AND INFECTION

Human gut microbes impact host serum metabolome and insulin sensitivity

(2016) Helle Krogh Pedersen et al.   NATURE

Pathogen mimicry of host protein-protein interfaces modulates immunity

(2016) Emine Guven-Maiorov et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Integration of Innate Immune Signaling

(2016) Christoph A. Thaiss et al.   TRENDS IN IMMUNOLOGY

Alterations of the human gut microbiome in multiple sclerosis

(2016) Sushrut Jangi et al.   Nature Communications

Host-Microbiota Interactions in the Pathogenesis of Antibiotic-Associated Diseases

(2016) Joshua S. Lichtman et al.   Cell Reports

A Structural View of Negative Regulation of the Toll-like Receptor-Mediated Inflammatory Pathway

(2015) Emine Guven-Maiorov et al.   BIOPHYSICAL JOURNAL

Host-Microbe Protein Interactions during Bacterial Infection

(2015) Devin K. Schweppe et al.   CHEMISTRY & BIOLOGY

Self or non-self? The multifaceted role of the microbiota in immune-mediated diseases

(2015) Martin A. Kriegel   CLINICAL IMMUNOLOGY

Advances in template-based protein docking by utilizing interfaces towards completing structural interactome

(2015) Serena Muratcioglu et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Colonic bacterial composition in Parkinson's disease

(2015) Ali Keshavarzian et al.   MOVEMENT DISORDERS

Mycobacterium tuberculosis suppresses innate immunity by coopting the host ubiquitin system

(2015) Jing Wang et al.   NATURE IMMUNOLOGY

Differential Expression and Roles of Staphylococcus aureus Virulence Determinants during Colonization and Disease

(2015) Amy Jenkins et al.   mBio

Network representations of immune system complexity

(2015) Naeha Subramanian et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

The Architecture of the TIR Domain Signalosome in the Toll-like Receptor-4 Signaling Pathway

(2015) Emine Guven-Maiorov et al.   Scientific Reports

Computational approaches for prediction of pathogen-host protein-protein interactions

(2015) Esmaeil Nourani et al.   Frontiers in Microbiology

Computational prediction of molecular pathogen-host interactions based on dual transcriptome data

(2015) Sylvie Schulze et al.   Frontiers in Microbiology

Hantaviral Proteins: Structure, Functions, and Role in Hantavirus Infection

(2015) Musalwa Muyangwa et al.   Frontiers in Microbiology

Subverting Toll-Like Receptor Signaling by Bacterial Pathogens

(2015) Victoria A. McGuire et al.   Frontiers in Immunology

The structural network of Interleukin-10 and its implications in inflammation and cancer

(2014) Ece Acuner-Ozbabacan et al.   BMC GENOMICS

The Microbiome in Inflammatory Bowel Disease: Current Status and the Future Ahead

(2014) Aleksandar D. Kostic et al.   GASTROENTEROLOGY

Salmonella Secreted Factor L Deubiquitinase of Salmonella typhimurium Inhibits NF- B, Suppresses I B  Ubiquitination and Modulates Innate Immune Responses

(2014) G. Le Negrate et al.   JOURNAL OF IMMUNOLOGY

A Staphylococcus aureus TIR Domain Protein Virulence Factor Blocks TLR2-Mediated NF-κB Signaling

(2014) Fatemeh Askarian et al.   Journal of Innate Immunity

Diet, microbiota and autoimmune diseases

(2014) SM Vieira et al.   LUPUS

Gut microbiota are related to Parkinson's disease and clinical phenotype

(2014) Filip Scheperjans et al.   MOVEMENT DISORDERS

The Pathogen-Host Interactions database (PHI-base): additions and future developments

(2014) Martin Urban et al.   NUCLEIC ACIDS RESEARCH

ViRBase: a resource for virus–host ncRNA-associated interactions

(2014) Yanhui Li et al.   NUCLEIC ACIDS RESEARCH

VirusMentha: a new resource for virus-host protein interactions

(2014) Alberto Calderone et al.   NUCLEIC ACIDS RESEARCH

VirHostNet 2.0: surfing on the web of virus/host molecular interactions data

(2014) Thibaut Guirimand et al.   NUCLEIC ACIDS RESEARCH

Non-Redundant Unique Interface Structures as Templates for Modeling Protein Interactions

(2014) Engin Cukuroglu et al.   PLoS One

Structure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2

(2014) D. Nesic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Use of Host-like Peptide Motifs in Viral Proteins Is a Prevalent Strategy in Host-Virus Interactions

(2014) Tzachi Hagai et al.   Cell Reports

SARS coronavirus papain-like protease inhibits the type I interferon signaling pathway through interaction with the STING-TRAF3-TBK1 complex

(2014) Xiaojuan Chen et al.   Protein & Cell

PHISTO: pathogen–host interaction search tool

(2013) Saliha Durmuş Tekir et al.   BIOINFORMATICS

Gastrointestinal cancers: Influence of gut microbiota, probiotics and prebiotics

(2013) Daniela Elena Serban   CANCER LETTERS

Protein interaction networks as starting points to identify novel antimicrobial drug targets

(2013) Roya Zoraghi et al.   CURRENT OPINION IN MICROBIOLOGY

Structure of the Toll/interleukin 1 receptor (TIR) domain of the immunosuppressiveBrucellaeffector BtpA/Btp1/TcpB

(2013) Burcu Kaplan-Türköz et al.   FEBS LETTERS

HoPaCI-DB: host-PseudomonasandCoxiellainteraction database

(2013) Sophie Bleves et al.   NUCLEIC ACIDS RESEARCH

PATRIC, the bacterial bioinformatics database and analysis resource

(2013) Alice R. Wattam et al.   NUCLEIC ACIDS RESEARCH

Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment

(2013) N. Iida et al.   SCIENCE

The structural network of inflammation and cancer: Merits and challenges

(2013) Emine Guven Maiorov et al.   SEMINARS IN CANCER BIOLOGY

Shigella flexneriT3SS effector IpaH4.5 modulates the host inflammatory response via interaction with NF-κB p65 protein

(2012) Fang Wang et al.   CELLULAR MICROBIOLOGY

Computational analysis of interactomes: Current and future perspectives for bioinformatics approaches to model the host–pathogen interaction space

(2012) Roland Arnold et al.   METHODS

Viral immune modulators perturb the human molecular network by common and unique strategies

(2012) Andreas Pichlmair et al.   NATURE

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins

(2012) Orit Rozenblatt-Rosen et al.   NATURE

Structure-based prediction of protein–protein interactions on a genome-wide scale

(2012) Qiangfeng Cliff Zhang et al.   NATURE

Templates are available to model nearly all complexes of structurally characterized proteins

(2012) P. J. Kundrotas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toward a three-dimensional view of protein networks between species

(2012) Eric A. Franzosa et al.   Frontiers in Microbiology

Infection Strategies of Bacterial and Viral Pathogens through Pathogen–Human Protein–Protein Interactions

(2012) Saliha Durmuş Tekir et al.   Frontiers in Microbiology

Insight into Bacterial Virulence Mechanisms against Host Immune Response via the Yersinia pestis-Human Protein-Protein Interaction Network

(2011) Huiying Yang et al.   INFECTION AND IMMUNITY

HCVpro: Hepatitis C virus protein interaction database

(2011) Samuel K. Kwofie et al.   INFECTION GENETICS AND EVOLUTION

A Physical Interaction Network of Dengue Virus and Human Proteins

(2011) Sudip Khadka et al.   MOLECULAR & CELLULAR PROTEOMICS

Structural principles within the human-virus protein-protein interaction network

(2011) E. A. Franzosa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Host-Pathogen interaction of human cyclophilin A and HIV-1 Vpr requires specific N-terminal and novel C-terminal domains

(2011) Sara MØ Solbak et al.   BMC STRUCTURAL BIOLOGY

HPIDB - a unified resource for host-pathogen interactions

(2010) Ranjit Kumar et al.   BMC BIOINFORMATICS

Metalloprotease type III effectors that specifically cleave JNK and NF-κB

(2010) Kobi Baruch et al.   EMBO JOURNAL

Enteropathogenic E. coli non-LEE encoded effectors NleH1 and NleH2 attenuate NF-κB activation

(2010) Sandhya V. Royan et al.   MOLECULAR MICROBIOLOGY

The Human-Bacterial Pathogen Protein Interaction Networks of Bacillus anthracis, Francisella tularensis, and Yersinia pestis

(2010) Matthew D. Dyer et al.   PLoS One

Structural space of protein-protein interfaces is degenerate, close to complete, and highly connected

(2010) M. Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein interface conservation across structure space

(2010) Q. C. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Tale of Two Toxins: Helicobacter Pylori CagA and VacA Modulate Host Pathways that Impact Disease

(2010) Kathleen R. Jones et al.   Frontiers in Microbiology

A Physical and Regulatory Map of Host-Influenza Interactions Reveals Pathways in H1N1 Infection

(2009) Sagi D. Shapira et al.   CELL

Severe Acute Respiratory Syndrome Coronavirus M Protein Inhibits Type I Interferon Production by Impeding the Formation of TRAF3·TANK·TBK1/IKKϵ Complex

(2009) Kam-Leung Siu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of Vaccinia Virus−Host Protein−Protein Interactions: Validations of Yeast Two-Hybrid Screenings

(2009) Leiliang Zhang et al.   JOURNAL OF PROTEOME RESEARCH

Targeting of immune signalling networks by bacterial pathogens

(2009) Igor E. Brodsky et al.   NATURE CELL BIOLOGY

Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics

(2009) Zhiwei Huang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Proteopathogen, a protein database for studyingCandida albicans- host interaction

(2009) Vital Vialás et al.   PROTEOMICS

Structural Microengineers: Pathogenic Escherichia coli Redesigns the Actin Cytoskeleton in Host Cells

(2009) Neta Sal-Man et al.   STRUCTURE

Topological properties of protein interaction networks from a structural perspective

(2008) Attila Gursoy et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Salmonella AvrA Coordinates Suppression of Host Immune and Apoptotic Defenses via JNK Pathway Blockade

(2008) Rheinallt M. Jones et al.   Cell Host & Microbe

The NY-1 Hantavirus Gn Cytoplasmic Tail Coprecipitates TRAF3 and Inhibits Cellular Interferon Responses by Disrupting TBK1-TRAF3 Complex Formation

(2008) P. J. Alff et al.   JOURNAL OF VIROLOGY

Hepatitis C virus infection protein network

(2008) B de Chassey et al.   Molecular Systems Biology

Subversion of Toll-like receptor signaling by a unique family of bacterial Toll/interleukin-1 receptor domain–containing proteins

(2008) Christine Cirl et al.   NATURE MEDICINE