Dynamics and heterogeneity of brain damage in multiple sclerosis

A minimal unified model of disease trajectories captures hallmarks of multiple sclerosis

(2017) Venkateshan Kannan et al.   MATHEMATICAL BIOSCIENCES

Is multiple sclerosis a length-dependent central axonopathy? The case for therapeutic lag and the asynchronous progressive MS hypotheses

(2017) Gavin Giovannoni et al.   Multiple Sclerosis and Related Disorders

Central nervous system inflammation across the age span

(2016) Amit Bar-Or et al.   CURRENT OPINION IN NEUROLOGY

Clinical and pathological insights into the dynamic nature of the white matter multiple sclerosis plaque

(2015) Josa M. Frischer et al.   ANNALS OF NEUROLOGY

The disruption of mitochondrial axonal transport is an early event in neuroinflammation

(2015) Oihana Errea et al.   Journal of Neuroinflammation

Pathological mechanisms in progressive multiple sclerosis

(2015) Don H Mahad et al.   LANCET NEUROLOGY

Neurodegeneration in multiple sclerosis is a process separate from inflammation: Yes

(2015) Céline Louapre et al.   Multiple Sclerosis Journal

Multiple sclerosis—a quiet revolution

(2015) Richard M. Ransohoff et al.   Nature Reviews Neurology

Neurodegeneration in multiple sclerosis is a process separate from inflammation: Yes

(2015) Céline Louapre et al.   Multiple Sclerosis Journal

Is it time to target no evident disease activity (NEDA) in multiple sclerosis?

(2015) Gavin Giovannoni et al.   Multiple Sclerosis and Related Disorders

Autoimmunity and tumor immunology: two facets of a probabilistic immune system

(2014) Jaime Iranzo et al.   BMC Systems Biology

Dynamics of Oligodendrocyte Generation and Myelination in the Human Brain

(2014) Maggie S.Y. Yeung et al.   CELL

Clinical Relevance of Brain Volume Measures in Multiple Sclerosis

(2014) Nicola De Stefano et al.   CNS DRUGS

Myelination at a glance

(2014) N. Snaidero et al.   JOURNAL OF CELL SCIENCE

Signaling networks in MS: A systems-based approach to developing new pharmacological therapies

(2014) Ekaterina Kotelnikova et al.   Multiple Sclerosis Journal

Identical lesion morphology in primary progressive and relapsing–remitting MS –an ultrahigh field MRI study

(2014) Joseph Kuchling et al.   Multiple Sclerosis Journal

Defining the clinical course of multiple sclerosis: The 2013 revisions

(2014) F. D. Lublin et al.   NEUROLOGY

Insufficient OPC migration into demyelinated lesions is a cause of poor remyelination in MS and mouse models

(2013) Amanda Boyd et al.   ACTA NEUROPATHOLOGICA

Network-Based Multiple Sclerosis Pathway Analysis with GWAS Data from 15,000 Cases and 30,000 Controls

(2013) Sergio E. Baranzini et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Oligodendrocyte Progenitor Cell Susceptibility to Injury in Multiple Sclerosis

(2013) Qiao-Ling Cui et al.   AMERICAN JOURNAL OF PATHOLOGY

Multiple sclerosis: Prospects and promise

(2013) Stephen L. Hauser et al.   ANNALS OF NEUROLOGY

Dynamic cross-regulation of antigen-specific effector and regulatory T cell subpopulations and microglia in brain autoimmunity

(2013) Sara Martinez-Pasamar et al.   BMC Systems Biology

Pathology and disease mechanisms in different stages of multiple sclerosis

(2013) Hans Lassmann   JOURNAL OF THE NEUROLOGICAL SCIENCES

Oxidative Stress and Proinflammatory Cytokines Contribute to Demyelination and Axonal Damage in a Cerebellar Culture Model of Neuroinflammation

(2013) Alessandra di Penta et al.   PLoS One

Predicting Relapsing-Remitting Dynamics in Multiple Sclerosis Using Discrete Distribution Models: A Population Approach

(2013) Nieves Velez de Mendizabal et al.   PLoS One

Innate immunity in the central nervous system

(2012) Richard M. Ransohoff et al.   JOURNAL OF CLINICAL INVESTIGATION

Progressive multiple sclerosis: pathology and pathogenesis

(2012) Hans Lassmann et al.   Nature Reviews Neurology

Will the real multiple sclerosis please stand up?

(2012) Peter K. Stys et al.   NATURE REVIEWS NEUROSCIENCE

Pathology of Demyelinating Diseases

(2011) Bogdan F.Gh. Popescu et al.   Annual Review of Pathology-Mechanisms of Disease

Modeling the effector - regulatory T cell cross-regulation reveals the intrinsic character of relapses in Multiple Sclerosis

(2011) Nieves Vélez de Mendizábal et al.   BMC Systems Biology

The molecular basis of neurodegeneration in multiple sclerosis

(2011) Hans Lassmann et al.   FEBS LETTERS

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

Brain Hodotopy: From Esoteric Concept to Practical Surgical Applications

(2011) Alessandro De Benedictis et al.   NEUROSURGERY

Demyelination versus remyelination in progressive multiple sclerosis

(2010) Stephan Bramow et al.   BRAIN

Systems biology and its application to the understanding of neurological diseases

(2009) Pablo Villoslada et al.   ANNALS OF NEUROLOGY

A methodology for performing global uncertainty and sensitivity analysis in systems biology

(2008) Simeone Marino et al.   JOURNAL OF THEORETICAL BIOLOGY

Mapping the brain pathways of declarative verbal memory: Evidence from white matter lesions in the living human brain

(2008) Jorge Sepulcre et al.   NEUROIMAGE