Receptor-binding domain of MERS-CoV with optimal immunogen dosage and immunization interval protects human transgenic mice from MERS-CoV infection

Recombinant Receptor-Binding Domains of Multiple Middle East Respiratory Syndrome Coronaviruses (MERS-CoVs) Induce Cross-Neutralizing Antibodies against Divergent Human and Camel MERS-CoVs and Antibody Escape Mutants

(2016) Wanbo Tai et al.   JOURNAL OF VIROLOGY

A phase 1, open-label, randomized study to compare the immunogenicity and safety of different administration routes and doses of virosomal influenza vaccine in elderly

(2016) Yotam Levin et al.   VACCINE

A recombinant receptor-binding domain of MERS-CoV in trimeric form protects human dipeptidyl peptidase 4 (hDPP4) transgenic mice from MERS-CoV infection

(2016) Wanbo Tai et al.   VIROLOGY

Introduction of neutralizing immunogenicity index to the rational design of MERS coronavirus subunit vaccines

(2016) Lanying Du et al.   Nature Communications

Identification of an ideal adjuvant for receptor-binding domain-based subunit vaccines against Middle East respiratory syndrome coronavirus

(2015) Naru Zhang et al.   Cellular & Molecular Immunology

Receptor Usage and Cell Entry of Porcine Epidemic Diarrhea Coronavirus

(2015) Chang Liu et al.   JOURNAL OF VIROLOGY

Characterization and Demonstration of the Value of a Lethal Mouse Model of Middle East Respiratory Syndrome Coronavirus Infection and Disease

(2015) Xinrong Tao et al.   JOURNAL OF VIROLOGY

Phase 1 Study of Pandemic H1 DNA Vaccine in Healthy Adults

(2015) Michelle C. Crank et al.   PLoS One

An orthopoxvirus-based vaccine reduces virus excretion after MERS-CoV infection in dromedary camels

(2015) B. L. Haagmans et al.   SCIENCE

Optimization of antigen dose for a receptor-binding domain-based subunit vaccine against MERS coronavirus

(2015) Jian Tang et al.   Human Vaccines & Immunotherapeutics

Recent Advances of Vaccine Adjuvants for Infectious Diseases

(2015) Sujin Lee et al.   Immune Network

Multi-Organ Damage in Human Dipeptidyl Peptidase 4 Transgenic Mice Infected with Middle East Respiratory Syndrome-Coronavirus

(2015) Guangyu Zhao et al.   PLoS One

Bat Origins of MERS-CoV Supported by Bat Coronavirus HKU4 Usage of Human Receptor CD26

(2014) Qihui Wang et al.   Cell Host & Microbe

Current advancements and potential strategies in the development of MERS-CoV vaccines

(2014) Naru Zhang et al.   Expert Review of Vaccines

Infant HIV Type 1 gp120 Vaccination Elicits Robust and Durable Anti-V1V2 Immunoglobulin G Responses and Only Rare Envelope-Specific Immunoglobulin A Responses

(2014) Genevieve G. Fouda et al.   JOURNAL OF INFECTIOUS DISEASES

Effects of Human Anti-Spike Protein Receptor Binding Domain Antibodies on Severe Acute Respiratory Syndrome Coronavirus Neutralization Escape and Fitness

(2014) J. Sui et al.   JOURNAL OF VIROLOGY

Receptor Recognition Mechanisms of Coronaviruses: a Decade of Structural Studies

(2014) Fang Li   JOURNAL OF VIROLOGY

Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus

(2014) Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Searching for an ideal vaccine candidate among different MERS coronavirus receptor-binding fragments—The importance of immunofocusing in subunit vaccine design

(2014) Cuiqing Ma et al.   VACCINE

Intranasal vaccination with recombinant receptor-binding domain of MERS-CoV spike protein induces much stronger local mucosal immune responses than subcutaneous immunization: Implication for designing novel mucosal MERS vaccines

(2014) Cuiqing Ma et al.   VACCINE

Detection of the Middle East Respiratory Syndrome Coronavirus Genome in an Air Sample Originating from a Camel Barn Owned by an Infected Patient

(2014) E. I. Azhar et al.   mBio

Middle East Respiratory Syndrome Coronavirus Quasispecies That Include Homologues of Human Isolates Revealed through Whole-Genome Analysis and Virus Cultured from Dromedary Camels in Saudi Arabia

(2014) T. Briese et al.   mBio

Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor

(2014) Lu Lu et al.   Nature Communications

Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4

(2013) Nianshuang Wang et al.   CELL RESEARCH

A family cluster of Middle East Respiratory Syndrome Coronavirus infections related to a likely unrecognized asymptomatic or mild case

(2013) Ali S. Omrani et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Structure of the Fusion Core and Inhibition of Fusion by a Heptad Repeat Peptide Derived from the S Protein of Middle East Respiratory Syndrome Coronavirus

(2013) J. Gao et al.   JOURNAL OF VIROLOGY

The Receptor Binding Domain of the New Middle East Respiratory Syndrome Coronavirus Maps to a 231-Residue Region in the Spike Protein That Efficiently Elicits Neutralizing Antibodies

(2013) H. Mou et al.   JOURNAL OF VIROLOGY

Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26

(2013) Guangwen Lu et al.   NATURE

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

(2013) V. Stalin Raj et al.   NATURE

Hospital Outbreak of Middle East Respiratory Syndrome Coronavirus

(2013) Abdullah Assiri et al.   NEW ENGLAND JOURNAL OF MEDICINE

Family Cluster of Middle East Respiratory Syndrome Coronavirus Infections

(2013) Ziad A. Memish et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Critical HA1 Neutralizing Domain of H5N1 Influenza in an Optimal Conformation Induces Strong Cross-Protection

(2013) Lanying Du et al.   PLoS One

A Truncated Receptor-Binding Domain of MERS-CoV Spike Protein Potently Inhibits MERS-CoV Infection and Induces Strong Neutralizing Antibody Responses: Implication for Developing Therapeutics and Vaccines

(2013) Lanying Du et al.   PLoS One

A safe and convenient pseudovirus-based inhibition assay to detect neutralizing antibodies and screen for viral entry inhibitors against the novel human coronavirus MERS-CoV

(2013) Guangyu Zhao et al.   Virology Journal

The history of MF59®adjuvant: a phoenix that arose from the ashes

(2012) Derek T O’Hagan et al.   Expert Review of Vaccines

Effects of adjuvants on IgG subclasses elicited by virus-like Particles

(2012) Maria Luisa Visciano et al.   Journal of Translational Medicine

Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia

(2012) Ali M. Zaki et al.   NEW ENGLAND JOURNAL OF MEDICINE

Development of a safe and convenient neutralization assay for rapid screening of influenza HA-specific neutralizing monoclonal antibodies

(2010) Lanying Du et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Potent and persistent antibody responses against the receptor-binding domain of SARS-CoV spike protein in recovered patients

(2010) Zhiliang Cao et al.   Virology Journal

Impact of prior or concomitant seasonal influenza vaccination on MF59-adjuvanted H1N1v vaccine (Focetria™) in adult and elderly subjects

(2009) R. Gasparini et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

The spike protein of SARS-CoV — a target for vaccine and therapeutic development

(2009) Lanying Du et al.   NATURE REVIEWS MICROBIOLOGY

Genetically Programmed Biases in Th1 and Th2 Immune Responses Modulate Atherogenesis

(2008) Stephanie Schulte et al.   AMERICAN JOURNAL OF PATHOLOGY