Linked read sequencing resolves complex genomic rearrangements in gastric cancer metastases

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Structural variation detection using next-generation sequencing data

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Haplotyping germline and cancer genomes with high-throughput linked-read sequencing

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Copy number analysis of whole-genome data using BIC-seq2 and its application to detection of cancer susceptibility variants

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(2015) Peter H. Sudmant et al.   NATURE

Systematic pan-cancer analysis of tumour purity

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Structural variation discovery in the cancer genome using next generation sequencing: Computational solutions and perspectives

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FGFR2 amplification has prognostic significance in gastric cancer: results from a large international multicentre study

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ETS fusion genes in prostate cancer

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Comprehensive molecular characterization of gastric adenocarcinoma

(2014) Adam J. Bass et al.   NATURE

Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture

(2014) Xingnan Li et al.   NATURE MEDICINE

LUMPY: a probabilistic framework for structural variant discovery

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Diverse Mechanisms of Somatic Structural Variations in Human Cancer Genomes

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FGFR2 Gene Amplification in Gastric Cancer Predicts Sensitivity to the Selective FGFR Inhibitor AZD4547

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Phenotypic impact of genomic structural variation: insights from and for human disease

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Detection of structural DNA variation from next generation sequencing data: a review of informatic approaches

(2013) Haley J. Abel et al.   Cancer Genetics

Detection of Redundant Fusion Transcripts as Biomarkers or Disease-Specific Therapeutic Targets in Breast Cancer

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Oncogenic FGFR3 gene fusions in bladder cancer

(2012) Sarah V. Williams et al.   HUMAN MOLECULAR GENETICS

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Rsf-1 overexpression correlates with poor prognosis and cell proliferation in colon cancer

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Overexpression of a Chromatin Remodeling Factor, RSF-1/HBXAP, Correlates with Aggressive Oral Squamous Cell Carcinoma

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Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

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Copy number variation detection in whole-genome sequencing data using the Bayesian information criterion

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Characterizing complex structural variation in germline and somatic genomes

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Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Monoclonal Antibodies to Fibroblast Growth Factor Receptor 2 Effectively Inhibit Growth of Gastric Tumor Xenografts

(2010) W.-m. Zhao et al.   CLINICAL CANCER RESEARCH

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Rsf-1, a Chromatin Remodeling Protein, Induces DNA Damage and Promotes Genomic Instability

(2010) Jim Jinn-Chyuan Sheu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genomic instability — an evolving hallmark of cancer

(2010) Simona Negrini et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Transcriptome sequencing to detect gene fusions in cancer

(2009) Christopher A. Maher et al.   NATURE

Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche

(2009) Akifumi Ootani et al.   NATURE MEDICINE

FGFR2-Amplified Gastric Cancer Cell Lines Require FGFR2 and Erbb3 Signaling for Growth and Survival

(2008) K. Kunii et al.   CANCER RESEARCH

Aberrant Receptor Internalization and Enhanced FRS2-dependent Signaling Contribute to the Transforming Activity of the Fibroblast Growth Factor Receptor 2 IIIb C3 Isoform

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