Divergent Metabolic Regulation of Autophagy and mTORC1—Early Events in Alzheimer’s Disease?
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Divergent Metabolic Regulation of Autophagy and mTORC1—Early Events in Alzheimer’s Disease?
Authors
Keywords
-
Journal
Frontiers in Aging Neuroscience
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2017-06-02
DOI
10.3389/fnagi.2017.00173
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Differential Activation of mTOR Complex 1 Signaling in Human Brain with Mild to Severe Alzheimer's Disease
- (2018) Yong-Xin Sun et al. JOURNAL OF ALZHEIMERS DISEASE
- Amino Acid Sensing by mTORC1: Intracellular Transporters Mark the Spot
- (2016) Deborah C.I. Goberdhan et al. Cell Metabolism
- Nutrient-sensing mTORC1: Integration of metabolic and autophagic signals
- (2016) Valerie P. Tan et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Brain-Wide Insulin Resistance, Tau Phosphorylation Changes, and Hippocampal Neprilysin and Amyloid- Alterations in a Monkey Model of Type 1 Diabetes
- (2016) J. Morales-Corraliza et al. JOURNAL OF NEUROSCIENCE
- Altered Expression of Human Mitochondrial Branched Chain Aminotransferase in Dementia with Lewy Bodies and Vascular Dementia
- (2016) Emma L. Ashby et al. NEUROCHEMICAL RESEARCH
- Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity
- (2016) Bernadette Carroll et al. eLife
- mTOR coordinates protein synthesis, mitochondrial activity and proliferation
- (2015) Masahiro Morita et al. CELL CYCLE
- Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre-clinical AD, amnestic mild cognitive impairment and late-stage AD
- (2015) Antonella Tramutola et al. JOURNAL OF NEUROCHEMISTRY
- Hippocampal Endosomal, Lysosomal, and Autophagic Dysregulation in Mild Cognitive Impairment
- (2015) Sylvia E. Perez et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Retromer in Alzheimer disease, Parkinson disease and other neurological disorders
- (2015) Scott A. Small et al. NATURE REVIEWS NEUROSCIENCE
- Differential regulation of mTORC1 by leucine and glutamine
- (2015) J. L. Jewell et al. SCIENCE
- Regulation of autophagy by amino acids and MTOR-dependent signal transduction
- (2014) Alfred J. Meijer et al. AMINO ACIDS
- The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration
- (2014) David Heras-Sandoval et al. CELLULAR SIGNALLING
- The relationship between cognitive performance and insulin resistance in non-diabetic patients with mild cognitive impairment
- (2014) Tae-Eun Kim et al. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
- Branched-chain amino acid-enriched supplementation improves insulin resistance in patients with chronic liver disease
- (2014) Takumi Kawaguchi et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- The general amino acid control pathway regulates mTOR and autophagy during serum/glutamine starvation
- (2014) Rui Chen et al. JOURNAL OF CELL BIOLOGY
- Hyperleucinemia causes hippocampal retromer deficiency linking diabetes to Alzheimer's disease
- (2014) Michael V. Morabito et al. NEUROBIOLOGY OF DISEASE
- The Sestrins Interact with GATOR2 to Negatively Regulate the Amino-Acid-Sensing Pathway Upstream of mTORC1
- (2014) Lynne Chantranupong et al. Cell Reports
- Dysglycemia, brain volume and vascular lesions on MRI in a memory clinic population
- (2013) Lieza G. Exalto et al. JOURNAL OF DIABETES AND ITS COMPLICATIONS
- Human Mild Traumatic Brain Injury Decreases Circulating Branched-Chain Amino Acids and Their Metabolite Levels
- (2013) Cameron B. Jeter et al. JOURNAL OF NEUROTRAUMA
- Enfermedad de Alzheimer y deterioro cognitivo asociado a la diabetes mellitus de tipo 2: relaciones e hipótesis
- (2013) R.O. Domínguez et al. NEUROLOGIA
- The lysosome: from waste bag to potential therapeutic target
- (2013) Hanna Appelqvist et al. Journal of Molecular Cell Biology
- Insulin resistance and the metabolism of branched-chain amino acids
- (2013) Jingyi Lu et al. Frontiers of Medicine
- Leucine and mTORC1: a complex relationship
- (2012) Kayleigh M. Dodd et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Insulin and IGF-1 signalling: longevity, protein homoeostasis and Alzheimer's disease
- (2012) Cora O'Neill et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- The retromer complex - endosomal protein recycling and beyond
- (2012) M. N. J. Seaman JOURNAL OF CELL SCIENCE
- Glutaminolysis Activates Rag-mTORC1 Signaling
- (2012) Raúl V. Durán et al. MOLECULAR CELL
- Alzheimer brain-derived amyloid β-protein impairs synaptic remodeling and memory consolidation
- (2012) Gilyana G. Borlikova et al. NEUROBIOLOGY OF AGING
- Changes in plasma phenylalanine, isoleucine, leucine, and valine are associated with significant changes in intracranial pressure and jugular venous oxygen saturation in patients with severe traumatic brain injury
- (2011) Raphael N. Vuille-Dit-Bille et al. AMINO ACIDS
- Validation of Plasma Branched Chain Amino Acids as Biomarkers in Huntington Disease
- (2011) Fanny Mochel et al. ARCHIVES OF NEUROLOGY
- Intranasal Insulin Therapy for Alzheimer Disease and Amnestic Mild Cognitive Impairment
- (2011) Suzanne Craft ARCHIVES OF NEUROLOGY
- Naturally Secreted Amyloid-β Increases Mammalian Target of Rapamycin (mTOR) Activity via a PRAS40-mediated Mechanism
- (2011) Antonella Caccamo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- p62 Is a Key Regulator of Nutrient Sensing in the mTORC1 Pathway
- (2011) Angeles Duran et al. MOLECULAR CELL
- Metabolite profiles and the risk of developing diabetes
- (2011) Thomas J Wang et al. NATURE MEDICINE
- The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
- (2011) Michelle C. Mendoza et al. TRENDS IN BIOCHEMICAL SCIENCES
- AMP kinase: the missing link between type 2 diabetes and neurodegenerative diseases?
- (2011) Mohamed Kodiha et al. TRENDS IN MOLECULAR MEDICINE
- Molecular Interplay between Mammalian Target of Rapamycin (mTOR), Amyloid-β, and Tau
- (2010) Antonella Caccamo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Conservation of Components in the Amino Acid Sensing Branch of the TOR Pathway in Yeast and Mammals
- (2010) Konstantin Kogan et al. JOURNAL OF MOLECULAR BIOLOGY
- Insulin deficiency exacerbates cerebral amyloidosis and behavioral deficits in an Alzheimer transgenic mouse model
- (2010) Xu Wang et al. Molecular Neurodegeneration
- Eaten alive: a history of macroautophagy
- (2010) Zhifen Yang et al. NATURE CELL BIOLOGY
- Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain
- (2010) Troy T. Rohn et al. NEUROBIOLOGY OF DISEASE
- Hippocampal memory processes are modulated by insulin and high-fat-induced insulin resistance
- (2010) Ewan C. McNay et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- Rag proteins regulate amino-acid-induced mTORC1 signalling
- (2009) Yasemin Sancak et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy
- (2009) Paul Nicklin et al. CELL
- Oligomeric aggregates of amyloid β peptide 1–42 activate ERK/MAPK in SH-SY5Y cells via the α7 nicotinic receptor
- (2009) Kirk F. Young et al. NEUROCHEMISTRY INTERNATIONAL
- Regulatory Control of Human Cytosolic Branched-Chain Aminotransferase by Oxidation and S-Glutathionylation and Its Interactions with Redox Sensitive Neuronal Proteins†
- (2008) Myra E. Conway et al. BIOCHEMISTRY
- Amino Acids Activate mTOR Complex 1 via Ca2+/CaM Signaling to hVps34
- (2008) Pawan Gulati et al. Cell Metabolism
- Autophagic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression
- (2008) Tadanori Hamano et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid β accumulation in mice
- (2008) Fiona Pickford et al. JOURNAL OF CLINICAL INVESTIGATION
- Nutrient sensing: TOR's Ragtime
- (2008) Alfred J. Meijer et al. NATURE CELL BIOLOGY
- Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking
- (2008) Chengyu Liang et al. NATURE CELL BIOLOGY
- Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling
- (2008) Aileen M. Moloney et al. NEUROBIOLOGY OF AGING
- The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1
- (2008) Y. Sancak et al. SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now