Molecular Mechanisms of Chronic Wasting Disease Prion Propagation

Human prion protein sequence elements impede cross-species chronic wasting disease transmission

(2015) Timothy D. Kurt et al.   JOURNAL OF CLINICAL INVESTIGATION

Use of a 2-aminothiazole to Treat Chronic Wasting Disease in Transgenic Mice

(2015) David Berry et al.   JOURNAL OF INFECTIOUS DISEASES

Insights into Chronic Wasting Disease and Bovine Spongiform Encephalopathy Species Barriers by Use of Real-Time Conversion

(2015) Kristen A. Davenport et al.   JOURNAL OF VIROLOGY

Host Determinants of Prion Strain Diversity Independent of Prion Protein Genotype

(2015) Jenna Crowell et al.   JOURNAL OF VIROLOGY

Deer Prion Proteins Modulate the Emergence and Adaptation of Chronic Wasting Disease Strains

(2015) Camilo Duque Velásquez et al.   JOURNAL OF VIROLOGY

Mucosal immunization with an attenuated Salmonella vaccine partially protects white-tailed deer from chronic wasting disease

(2015) Fernando Goñi et al.   VACCINE

Grass Plants Bind, Retain, Uptake, and Transport Infectious Prions

(2015) Sandra Pritzkow et al.   Cell Reports

Chronic Wasting Disease of Cervids: Current Knowledge and Future Perspectives

(2015) Nicholas J. Haley et al.   Annual Review of Animal Biosciences

Bayesian Modeling of Prion Disease Dynamics in Mule Deer Using Population Monitoring and Capture-Recapture Data

(2015) Chris Geremia et al.   PLoS One

Detection of Chronic Wasting Disease in the Lymph Nodes of Free-Ranging Cervids by Real-Time Quaking-Induced Conversion

(2014) Nicholas J. Haley et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Quantitative assessment of prion infectivity in tissues and body fluids by real-time quaking-induced conversion

(2014) D. M. Henderson et al.   JOURNAL OF GENERAL VIROLOGY

Prion Transmission Prevented by Modifying the β2-α2 Loop Structure of Host PrP C

(2014) Timothy D. Kurt et al.   JOURNAL OF NEUROSCIENCE

“Atypical” Chronic Wasting Disease in PRNP Genotype 225FF Mule Deer

(2014) Lisa L. Wolfe et al.   JOURNAL OF WILDLIFE DISEASES

Quinacrine promotes replication and conformational mutation of chronic wasting disease prions

(2014) J. Bian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural effects of PrP polymorphisms on intra- and interspecies prion transmission

(2014) R. Angers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lesion Profiling and Subcellular Prion Localization of Cervid Chronic Wasting Disease in Domestic Cats

(2014) D. M. Seelig et al.   VETERINARY PATHOLOGY

Experimental Chronic Wasting Disease in Wild Type VM Mice

(2013) Yoon-Hee LEE et al.   JOURNAL OF VETERINARY MEDICAL SCIENCE

Assessing the Susceptibility of Transgenic Mice Overexpressing Deer Prion Protein to Bovine Spongiform Encephalopathy

(2013) C. M. Vickery et al.   JOURNAL OF VIROLOGY

ESTIMATING CHRONIC WASTING DISEASE EFFECTS ON MULE DEER RECRUITMENT AND POPULATION GROWTH

(2013) Jessie Dulberger et al.   JOURNAL OF WILDLIFE DISEASES

Failure of Fallow Deer (Dama dama) to Develop Chronic Wasting Disease When Exposed to a Contaminated Environment and Infected Mule Deer (Odocoileus hemionus)

(2013) Jack C. Rhyan et al.   JOURNAL OF WILDLIFE DISEASES

DETECTION OF PrPCWD IN FECES FROM NATURALLY EXPOSED ROCKY MOUNTAIN ELK (CERVUS ELAPHUS NELSONI) USING PROTEIN MISFOLDING CYCLIC AMPLIFICATION

(2013) Bruce Pulford et al.   JOURNAL OF WILDLIFE DISEASES

Mother to Offspring Transmission of Chronic Wasting Disease in Reeves’ Muntjac Deer

(2013) Amy V. Nalls et al.   PLoS One

Rapid Antemortem Detection of CWD Prions in Deer Saliva

(2013) Davin M. Henderson et al.   PLoS One

Drug resistance confounding prion therapeutics

(2013) D. B. Berry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic Wasting Disease in Bank Voles: Characterisation of the Shortest Incubation Time Model for Prion Diseases

(2013) Michele Angelo Di Bari et al.   PLoS Pathogens

Prion inhibition with multivalent PrPSc binding compounds

(2012) Charles E. Mays et al.   BIOMATERIALS

Susceptibility of Domestic Cats to Chronic Wasting Disease

(2012) C. K. Mathiason et al.   JOURNAL OF VIROLOGY

Experimental Oral Transmission of Chronic Wasting Disease to Reindeer (Rangifer tarandus tarandus)

(2012) Gordon B. Mitchell et al.   PLoS One

An Enzymatic Treatment of Soil-Bound Prions Effectively Inhibits Replication

(2011) Samuel E. Saunders et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Generation of a New Form of Human PrPScin Vitroby Interspecies Transmission from Cervid Prions

(2011) Marcelo A. Barria et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformational Transformation and Selection of Synthetic Prion Strains

(2011) Sina Ghaemmaghami et al.   JOURNAL OF MOLECULAR BIOLOGY

Chronic Wasting Disease in a Wisconsin White-Tailed Deer Farm

(2011) Delwyn P. Keane et al.   JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION

In Vivo Comparison of Chronic Wasting Disease Infectivity from Deer with Variation at Prion Protein Residue 96

(2011) B. Race et al.   JOURNAL OF VIROLOGY

Detection of Chronic Wasting Disease Prions in Salivary, Urinary, and Intestinal Tissues of Deer: Potential Mechanisms of Prion Shedding and Transmission

(2011) N. J. Haley et al.   JOURNAL OF VIROLOGY

Modeling Routes of Chronic Wasting Disease Transmission: Environmental Prion Persistence Promotes Deer Population Decline and Extinction

(2011) Emily S. Almberg et al.   PLoS One

Transmission of Chronic Wasting Disease Identifies a Prion Strain Causing Cachexia and Heart Infection in Hamsters

(2011) Richard A. Bessen et al.   PLoS One

Accelerated High Fidelity Prion Amplification Within and Across Prion Species Barriers

(2011) Kristi M. Green et al.   PLoS Pathogens

A molecular switch controls interspecies prion disease transmission in mice

(2010) Christina J. Sigurdson et al.   JOURNAL OF CLINICAL INVESTIGATION

Chronic wasting disease prions are not transmissible to transgenic mice overexpressing human prion protein

(2010) M. K. Sandberg et al.   JOURNAL OF GENERAL VIROLOGY

Horse Prion Protein NMR Structure and Comparisons with Related Variants of the Mouse Prion Protein

(2010) Daniel R. Pérez et al.   JOURNAL OF MOLECULAR BIOLOGY

Cell-Based Quantification of Chronic Wasting Disease Prions

(2010) J. Bian et al.   JOURNAL OF VIROLOGY

Prion disease susceptibility is affected by  -structure folding propensity and local side-chain interactions in PrP

(2010) M. Q. Khan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Darwinian Evolution of Prions in Cell Culture

(2010) J. Li et al.   SCIENCE

Prion Strain Mutation Determined by Prion Protein Conformational Compatibility and Primary Structure

(2010) R. C. Angers et al.   SCIENCE

Immunohistochemical and biochemical characteristics of BSE and CWD in experimentally infected European red deer (Cervus elaphus elaphus)

(2009) Stuart Martin et al.   BMC Veterinary Research

Host culling as an adaptive management tool for chronic wasting disease in white-tailed deer: a modelling study

(2009) Gideon Wasserberg et al.   JOURNAL OF APPLIED ECOLOGY

Prion Protein NMR Structure from Tammar Wallaby (Macropus eugenii) Shows that the β2–α2 Loop Is Modulated by Long-Range Sequence Effects

(2009) Barbara Christen et al.   JOURNAL OF MOLECULAR BIOLOGY

Prion Infectivity in Fat of Deer with Chronic Wasting Disease

(2009) B. Race et al.   JOURNAL OF VIROLOGY

Chronic Wasting Disease (CWD) Susceptibility of Several North American Rodents That Are Sympatric with Cervid CWD Epidemics

(2009) D. M. Heisey et al.   JOURNAL OF VIROLOGY

Asymptomatic deer excrete infectious prions in faeces

(2009) Gültekin Tamgüney et al.   NATURE

Detection of CWD Prions in Urine and Saliva of Deer by Transgenic Mouse Bioassay

(2009) Nicholas J. Haley et al.   PLoS One

Detection of Sub-Clinical CWD Infection in Conventional Test-Negative Deer Long after Oral Exposure to Urine and Feces from CWD+ Deer

(2009) Nicholas J. Haley et al.   PLoS One

Trans-species amplification of PrPCWD and correlation with rigid loop 170N

(2009) Timothy D. Kurt et al.   VIROLOGY

Preliminary Observations on the Experimental Transmission of Chronic Wasting Disease (CWD) from Elk and White-Tailed Deer to Fallow Deer

(2008) A.N. Hamir et al.   JOURNAL OF COMPARATIVE PATHOLOGY

Experimental Chronic Wasting Disease (CWD) in the Ferret

(2008) C.J. Sigurdson et al.   JOURNAL OF COMPARATIVE PATHOLOGY

The elk PRNP codon 132 polymorphism controls cervid and scrapie prion propagation

(2008) K. M. Green et al.   JOURNAL OF GENERAL VIROLOGY

Gene expression profile of quinacrine-cured prion-infected mouse neuronal cells

(2008) Carlo Fasano et al.   JOURNAL OF NEUROCHEMISTRY

Lions and Prions and Deer Demise

(2008) Michael W. Miller et al.   PLoS One

De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis

(2008) C. J. Sigurdson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vitro strain adaptation of CWD prions by serial protein misfolding cyclic amplification

(2008) Crystal Meyerett et al.   VIROLOGY