Article
Biochemistry & Molecular Biology
Xiaojing Huang, Daniel Winter, Dominic. J. J. Glover, Claudiu. T. T. Supuran, William. A. A. Donald
Summary: Carbonic anhydrases (CAs) are metalloenzymes that play important roles in cellular processes and have been implicated in various diseases. Phosphorylation, a common post-translational modification of CAs, can significantly impact their catalytic activity and drug-binding capabilities. This study highlights the potential regulatory role of phosphorylation in CA activity and its effect on small molecule drug binding.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Plant Sciences
Naveen Sharma, John E. Froehlich, Rees Rillema, Daniel A. Raba, Taylor Chambers, Cheryl A. Kerfeld, David M. Kramer, Berkley Walker, Federica Brandizzi
Summary: This study characterized two plastidial beta carbonic anhydrases, beta CA1 and beta CA5, in Arabidopsis plants. The results showed that both proteins are localized in the chloroplast stroma and that the loss of beta CA5 induces the expression of beta CA1. The study also revealed that the two enzymes have different enzymatic kinetics and physiological relevance. Rating: 8 out of 10
Article
Plant Sciences
Lei Wang, Qing-Lai Dang
Summary: The study revealed significant differences in leaf morphology and growth characteristics between shoots originated from different types of buds, with axillary buds producing shorter leaves with higher specific leaf area, and adventitious buds producing longer leaves with a lanceolate shape. Shoots from different types of buds also exhibited different growth rates and biomass, with variations in direction depending on the population of the mother tree.
PHYSIOLOGIA PLANTARUM
(2022)
Article
Environmental Sciences
Yuhang Zhou, Xinjie Li, Jiaqi Chen, Wenbing Li, Fan Wang
Summary: Wastewater treatment technology based on algae-bacteria combines pollutant purification, CO2 reduction, and clean energy production, providing new insights into climate solutions. This study explores the reciprocal mechanisms between algae and bacteria, focusing on the CO2 fixation capacity of immobilized algae-bacteria symbiotic particles (ABSPs) through physiological and biochemical analyses. The results demonstrate that ABSPs enhance the CO2 fixation capacity of microalgae by promoting growth and photosynthetic activity, primarily through activation of the photosynthetic system and promotion of the Calvin cycle.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Agriculture, Multidisciplinary
Seung Kyou You, Hyeon Min Park, Myeong-Eun Lee, Young Jin Ko, Dong-Hyeuk Hwang, Jun Won Oh, Sung Ok Han
Summary: Metabolic engineering of non-photosynthetic microorganisms to increase the utilization of CO2 has been shown to significantly increase the production of fatty acids in the oleaginous yeast Yarrowia lipolytica. The introduction of a CO2 utilization pathway resulted in a 1.5-fold increase in fatty acid production and a 11.6% increase in linoleic acid composition compared to the wild-type strain, demonstrating the potential for developing efficient and eco-friendly processes utilizing CO2.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Plant Sciences
Lian Zhou, Xiaoqin Xiang, Dongpu Ji, Qiulan Chen, Tengfei Ma, Jiuguang Wang, Chaoxian Liu
Summary: The study shows that ZmCA4 plays a critical role in photosynthesis in maize by modulating CO2 signaling regulation through its interaction with ZmPIP2;6. This provides insights into the potential genetic value of ZmCA4 for improving maize yield.
PLANT AND CELL PHYSIOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Ferran Esteve, Fidan Rahmatova, Jean-Marie Lehn
Summary: This study reveals the remarkable effect of supramolecular multivalency on increasing imine stability. By synthesizing a series of reactive aldehydes bearing supramolecularly-active sites, it was found that decreasing the degree of supramolecular multivalency significantly decreased imine yields. Preliminary results on protein bioconjugation demonstrated the ability to dynamically inhibit the activity of carbonic anhydrase and recover its initial activity with a suitable chemical effector.
Article
Chemistry, Multidisciplinary
Annachiara Tinivella, Luca Pinzi, Giulio Rastelli
Summary: The development of selective inhibitors for human Carbonic Anhydrase isoforms IX and XII is essential for cancer drug research. Machine learning classification models trained on high confidence data from ChEMBL were used to predict ligand activity and selectivity profiles. The results outperformed classic models built with a priori activity thresholds.
JOURNAL OF CHEMINFORMATICS
(2021)
Article
Multidisciplinary Sciences
Juanli Chen, Xueyong Zhao, Yuqiang Li, Yongqing Luo, Yaqiu Zhang, Mei Liu, Yan Li
Summary: The drought resistance of psammophytes plays a crucial role in their survival and growth. In a pot experiment, it was observed that Agriophyllum squarrosum is better adapted to arid environments compared to Setaria viridis, although high soil moisture content is not conducive to normal growth of Agriophyllum squarrosum. The physiological characteristics of both species, including relative water content, chlorophyll content, and enzyme activities, were affected by drought and rehydration treatments.
SCIENTIFIC REPORTS
(2021)
Article
Agronomy
Mahmoud F. Seleiman, Awais Ahmad, Bushra Ahmed Alhammad, Elkamil Tola
Summary: The study evaluated the effectiveness of zinc oxide nanoparticles as salinity mitigators in maize plants. The results showed that foliar treatment with zinc oxide nanoparticles successfully alleviated the negative effects of salinity and significantly improved various parameters.
Article
Biology
Cheyenne M. Anderson, Erin M. Mattoon, Ningning Zhang, Eric Becker, William McHargue, Jiani Yang, Dhruv Patel, Oliver Dautermann, Scott A. M. McAdam, Tonantzin Tarin, Sunita Pathak, Tom J. Avenson, Jeffrey Berry, Maxwell Braud, Krishna K. Niyogi, Margaret Wilson, Dmitri A. Nusinow, Rodrigo Vargas, Kirk J. Czymmek, Andrea L. Eveland, Ru Zhang
Summary: The study exposed C-4 model plant Setaria viridis to high light or high temperature treatments and observed reduction in photosynthetic efficiency. Differences in key pathways and responses in different cells were identified. Unique acclimation and stress response strategies in C-4 plants were revealed.
COMMUNICATIONS BIOLOGY
(2021)
Article
Plant Sciences
Li Yang, Yanshou Shi, Xiao Ruan, Qingfei Wu, Aili Qu, Minfen Yu, Xiaohua Qian, Zhaohui Li, Zhijun Ke, Liping He, Yingxian Zhao, Qiang Wang
Summary: This study found that moderate concentrations of NaCl treatment significantly increased the accumulation of phenolic acids, steroids, and polysaccharides in Tetrastigma hemsleyanum, as well as the total content of flavonoids. Salt stress had effects on the photosynthetic characteristics of T. hemsleyanum and the selectivity of flavonoid biosynthesis pathways. Moderate concentrations of NaCl treatment improved photosynthesis and secondary metabolite accumulation in T. hemsleyanum.
ENVIRONMENTAL AND EXPERIMENTAL BOTANY
(2022)
Article
Chemistry, Medicinal
Krishna Kartheek Chinchilli, Ravikumar Akunuri, Shaik Mahammad Ghouse, Devandla Soujanya, Andrea Angeli, Ramulu Parupalli, Mohammed Arifuddin, Venkata Madhavi Yaddanapudi, Claudiu T. Supuran, Srinivas Nanduri
Summary: Rhodanine and its derivatives are a valuable class of heterocycles with diverse biological properties, including anticancer, antibacterial, and anti-mycobacterial activities. In this study, new Rhodanine derivatives were synthesized and evaluated for their inhibitory activity against carbonic anhydrase isoforms. The compounds showed good inhibitory activity against cytosolic isoform hCA II and tumor-associated hCA IX. The mechanism of action was supported by molecular docking studies.
ARCHIV DER PHARMAZIE
(2023)
Article
Environmental Sciences
Prachi Singh, Kunal R. Jain, Varun Shah, Datta Madamwar
Summary: This study investigated the microbial community of the flat salt basin of White Rann of Kachchh, Gujarat, India, and found that salinity, TOC, EC, and sulphate concentration may be the primary drivers of community distribution. Surprisingly, the expected effect of salinity gradient on microbial composition was found to be less significant.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Chemistry, Medicinal
Niccolo Chiaramonte, Andrea Angeli, Silvia Sgambellone, Alessandro Bonardi, Alessio Nocentini, Gianluca Bartolucci, Laura Braconi, Silvia Dei, Laura Lucarini, Elisabetta Teodori, Paola Gratteri, Bernhard Wuensch, Claudiu T. Supuran, Maria Novella Romanelli
Summary: Targeting carbonic anhydrases is a strategy for treating various diseases. In this study, a new series of chiral piperazine compounds was synthesized to widen the structure-activity relationships of potent human carbonic anhydrase inhibitors. Some of the synthesized compounds showed high inhibitory activity.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2022)
Article
Plant Sciences
Kaiyan Zhang, Yanyou Wu, Yue Su, Haitao Li
Summary: The proportions of assimilated nitrate and ammonium in Brassica napus plantlets grown at different ammonium/nitrate ratios were quantified using stable nitrogen isotope tracer technique. The utilization proportions of sucrose and CO2 were quantified by a two end-member isotope mixing model. Increasing the nitrate concentration promoted the ammonium assimilation and enhanced the ammonium utilization coefficient. The amount of nitrogen derived from nitrate assimilation increased with increasing nitrate concentration, while the nitrate utilization coefficient showed no significant change.
Article
Agronomy
Kai Yao, Yanqing Wang, Yanyou Wu
Summary: Little is known about the competition and niche differentiation of water and nutrients between angiosperm and gymnosperm tree species under prolonged drought stress, especially in fragile environments. In this study, we found that soil water content significantly affected the N content, δ13C, δ15N, phosphomonoesterase, phosphodiesterase, g(s), and foliage water content. N competition between the two plants could be alleviated through niche differentiation, but the niche differentiation of the P source was lost under drought stress. Interspecific competition also affected foliage water content, WUE, N contents, and N and P sources. Our results suggest that the effect of interspecific water competition should be seriously considered in mixed forests in semiarid areas.
Article
Agronomy
Antong Xia, Yanyou Wu
Summary: In this study, the authors evaluated the absorption and utilization of nitrate, ammonium, and inorganic carbon during bicarbonate supply in different plant species. They found that Orychophragmus violaceus showed higher efficiency in nitrate assimilation and utilization, while higher bicarbonate levels promoted ammonium utilization and water use efficiency in both Ov and Brassica napus. However, high bicarbonate levels inhibited total inorganic carbon and nitrogen assimilation, leading to growth suppression in Bn compared to Ov. The study highlights the adaptability of Ov to karst habitats.
Review
Agronomy
Yanyou Wu, Yansheng Wu
Summary: Plant photosynthesis and rock chemical dissolution are two of the most important CO2 sequestration processes on Earth. The coupling of karstification and photosynthesis can increase the capacity of carbon sinks. Developing karst-adaptable plants can strengthen the coupling and improve the carbon sink capacity of karst ecosystems.
Article
Agronomy
Sen ao, Yanyou Wu
Summary: Soil dissolved inorganic carbon (DIC) has a varying impact on leaf photosynthesis in karst habitats, with spatial heterogeneity. This study enhances our understanding of plant adaptation to the soil conditions in karst habitats and the acquisition of additional carbon.
Article
Plant Sciences
Yongdao Gao, Chang Cai, Qiaoan Yang, Wenxuan Quan, Chaochan Li, Yanyou Wu
Summary: In heterogeneous landscapes in southwestern China, Bletilla striata demonstrates different electrophysiological and morphological characteristics under different water conditions. Under light drought conditions, B. striata shows higher physiological activity, good morphological characteristics, and higher adaptability. Moderate drought can improve the quality of B. striata and promote its cultivation in mildly arid areas.
Article
Geosciences, Multidisciplinary
Tengxiang Xie, Lihua Zhao, Yanyou Wu
Summary: Enhanced silicate dissolution by green microalgae, such as Chlamydomonas reinhardtii and Chlorella pyrenoedosa, has been found to effectively remove CO2 from the atmosphere. The presence of these microalgae significantly enhances the dissolution rate of peridotite, with a higher effect observed in the early stage of interaction. It is estimated that one milligram of chlorophyll-a biomass from these microalgae can remove 0.44 and 0.24 mg CO2 per day, respectively, through accelerated dissolution. However, the issue of decelerated dissolution rate over time needs to be addressed to improve CO2 sequestration efficiency.
JOURNAL OF ASIAN EARTH SCIENCES
(2023)
Article
Geochemistry & Geophysics
Yanyou Wu
Summary: Carbon neutrality is a widely concerned and highly valued issue for many countries. The biosphere provides a good example for human beings to achieve carbon neutrality by balancing oxygen and CO2. Photosystem II acts as a carbonic anhydrase in the process of photosynthetic oxygen evolution, initiating the carbon and water neutrality. The study also found that bicarbonate can promote photosynthetic oxygen evolution, and that photosynthetic oxygen evolution can come from both bicarbonate and water. This research sheds light on the understanding of photosynthesis and its role in achieving carbon neutrality in nature.
Article
Agronomy
Kaiyan Zhang, Furong Zhang, Haitao Li, Yue Su, Yanyou Wu
Summary: Insufficient inorganic nitrogen in karst soils often leads to poor growth in artificial young forests. However, little is known about the assimilatory demand of nitrate for the whole plant and the partitioning of nitrate assimilation in roots and leaves of woody plants in karst habitats. This study used the isotope mass balance approach to quantify the δ^15N values of N assimilates in different plant organs and in whole plants of Broussonetia papyrifera seedlings grown under different nitrate concentrations. The δ^15N values of N assimilates in the whole seedlings showed an increasing trend with higher nitrate concentration. Increasing the nitrate supply decreased the leaf-root difference in δ^15N values of N assimilates. Quantifying the δ^15N values of N assimilates in B. papyrifera seedlings grown under different nitrate concentrations contributes to estimating their assimilatory demand for nitrate, while the leaf-root difference in δ^15N values can be used to estimate the partitioning of nitrate assimilation between roots and leaves.
Article
Plant Sciences
Xiaopan Zhao, Yanyou Wu, Deke Xing, Haitao Li, Furong Zhang
Summary: The karst carbon sink caused by rock outcrops affects the physiological processes of plants by enriching bicarbonate in the soil. This study compared the water use efficiency of Lonicera japonica and Parthenocissus quinquefolia under different rock outcrop habitats, and found that Lonicera japonica was more adaptable to karst environments.
Editorial Material
Horticulture
Yanyou Wu
Summary: Abiotic stress factors have a significant impact on various aspects of plant physiology. The research in this Special Issue explores the deeper meaning of plant physiology, such as plant electrophysiology, under abiotic stress and expands the definition of abiotic stress factors to include environmental pollutants. The selected papers published in this Special Issue also demonstrate their potential value in the production of horticultural plants.
Article
Agronomy
Yanyou Wu, Yansheng Wu
Article
Agronomy
Haitao Li, Jiamei Lv, Yue Su, Yanyou Wu
Summary: This study investigated the effects of varying concentrations of sodium bicarbonate on the growth, electrophysiological properties, intracellular water metabolism, nutrient transport, photosynthesis, and chlorophyll fluorescence of Coix lacryma-jobi L. It was found that a concentration of 2.0 mmol L-1 sodium bicarbonate effectively improved the biomass formation and various physiological parameters of Coix lacryma-jobi L., while concentrations of 7.0 and 12.0 mmol L-1 had inhibitory effects on photosynthesis and plant growth. The study highlights the importance of appropriate bicarbonate levels in enhancing plant physiological functions and suggests that electrophysiological measurement is superior to photosynthesis measurement for monitoring these responses.
Article
Plant Sciences
Antong Xia, Yanyou Wu, Jiqian Xiang, Hongqing Yin, Jiajia Ming, Zhanghui Qin
Summary: The study found that in karst habitats, bicarbonate and ammonium have varying effects on different plants, with some plants shifting towards PPP to promote ammonium utilization. Quantifying the relationships between EMP, PPP, NO3-, and NH4+ utilization can help improve carbon and nitrogen use efficiency in plants.
Article
Geochemistry & Geophysics
Yanyou Wu, Shaogang Guo
Summary: Photosynthesis is the most important biochemical reaction on Earth, which converts light energy into chemical energy. Recent studies suggest that bicarbonate plays a crucial role in photosynthesis, working together with water in a 1:1 stoichiometric relationship. This finding provides a logical explanation for the coordination between light and dark reactions during photosynthesis.