Varying Intolerance of Gene Pathways to Mutational Classes Explain Genetic Convergence across Neuropsychiatric Disorders

Title
Varying Intolerance of Gene Pathways to Mutational Classes Explain Genetic Convergence across Neuropsychiatric Disorders
Authors
Keywords
de novo mutations, missense mutations, loss of function mutations, intellectual disability, schizophrenia, autism spectrum disorders, gene expression, constrained genes, systems biology, brain development
Journal
Cell Reports
Volume 18, Issue 9, Pages 2217-2227
Publisher
Elsevier BV
Online
2017-03-01
DOI
10.1016/j.celrep.2017.02.007

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