Conformational Freedom of the LRP6 Ectodomain Is Regulated by N-glycosylation and the Binding of the Wnt Antagonist Dkk1

Title
Conformational Freedom of the LRP6 Ectodomain Is Regulated by N-glycosylation and the Binding of the Wnt Antagonist Dkk1
Authors
Keywords
LRP6, Wnt signal, negative-stain electron microscopy, Dkk1, single particle analysis, N-glycosylation, conformational flexibility, receptor ectodomain
Journal
Cell Reports
Volume 18, Issue 1, Pages 32-40
Publisher
Elsevier BV
Online
2017-01-05
DOI
10.1016/j.celrep.2016.12.017

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