An Ancient Pseudoknot in TNF-α Pre-mRNA Activates PKR, Inducing eIF2α Phosphorylation that Potently Enhances Splicing

Published 2017 View Full Article

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Title
An Ancient Pseudoknot in TNF-α Pre-mRNA Activates PKR, Inducing eIF2α Phosphorylation that Potently Enhances Splicing
Authors
Keywords
inflammatory response, tumor necrosis factor, regulation of mRNA splicing, integrated cellular stress response, stress kinase PKR, translation initiation factor eIF2, eIF2α phosphorylation, RNA activator of PKR, RNA pseudoknot, phylogenetic conservation of RNA structure
Journal
Cell Reports
Volume 20, Issue 1, Pages 188-200
Publisher
Elsevier BV
Online
2017-07-06
DOI
10.1016/j.celrep.2017.06.035

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