The lncRNA MEG3 downregulation leads to osteoarthritis progression via miR-16/SMAD7 axis

Long noncoding RNAs in osteoarthritis

(2017) Shi-de Jiang et al.   JOINT BONE SPINE

Osteoarthritis year in review 2016: biology

(2017) E.N. Blaney Davidson et al.   OSTEOARTHRITIS AND CARTILAGE

Oxidative stress, autophagy, epigenetic changes and regulation by miRNAs as potential therapeutic targets in osteoarthritis

(2016) Sergio Portal-Núñez et al.   BIOCHEMICAL PHARMACOLOGY

Long non-coding RNA MEG3 inhibits microRNA-125a-5p expression and induces immune imbalance of Treg/Th17 in immune thrombocytopenic purpura

(2016) Jian-Qin Li et al.   BIOMEDICINE & PHARMACOTHERAPY

New developments in osteoarthritis and cartilage biology

(2016) Blandine Poulet et al.   CURRENT OPINION IN PHARMACOLOGY

Upregulation of lncRNA HOTAIR contributes to IL-1β-induced MMP overexpression and chondrocytes apoptosis in temporomandibular joint osteoarthritis

(2016) Chunping Zhang et al.   GENE

Global molecular changes in a tibial compression induced ACL rupture model of post-traumatic osteoarthritis

(2016) Jiun C. Chang et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Long non-coding RNA NEAT1 promotes non-small cell lung cancer progression through regulation of miR-377-3p-E2F3 pathway

(2016) Chengcao Sun et al.   Oncotarget

Review: Long Noncoding RNAs in the Regulation of Inflammatory Pathways in Rheumatoid Arthritis and Osteoarthritis

(2016) Mark J. Pearson et al.   Arthritis & Rheumatology

Emerging targets in osteoarthritis therapy

(2015) Mary B Goldring et al.   CURRENT OPINION IN PHARMACOLOGY

MicroRNA-16-5p Controls Development of Osteoarthritis by Targeting SMAD3 in Chondrocytes

(2015) Lisong Li et al.   CURRENT PHARMACEUTICAL DESIGN

Noncoding RNAs, cytokines, and inflammation-related diseases

(2015) José Luiz Marques-Rocha et al.   FASEB JOURNAL

Smad7 Protein Interacts with Receptor-regulated Smads (R-Smads) to Inhibit Transforming Growth Factor-β (TGF-β)/Smad Signaling

(2015) Xiaohua Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PCGEM1 stimulates proliferation of osteoarthritic synoviocytes by acting as a sponge for miR-770

(2015) Yeonho Kang et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

miRTarBase 2016: updates to the experimentally validated miRNA-target interactions database

(2015) Chih-Hung Chou et al.   NUCLEIC ACIDS RESEARCH

The lncRNA H19 promotes epithelial to mesenchymal transition by functioning as miRNA sponges in colorectal cancer

(2015) Wei-Cheng Liang et al.   Oncotarget

The human long noncoding RNA lnc-IL7R regulates the inflammatory response

(2014) Huachun Cui et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A long non-coding RNA, GAS5, plays a critical role in the regulation of miR-21 during osteoarthritis

(2014) Jinsoo Song et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Destabilization of the medial meniscus leads to subchondral bone defects and site-specific cartilage degeneration in an experimental rat model

(2014) H. Iijima et al.   OSTEOARTHRITIS AND CARTILAGE

A Network Based Method for Analysis of lncRNA-Disease Associations and Prediction of lncRNAs Implicated in Diseases

(2014) Xiaofei Yang et al.   PLoS One

MEG3: a novel long noncoding potentially tumour-suppressing RNA in meningiomas

(2013) Vladimir Balik et al.   JOURNAL OF NEURO-ONCOLOGY

miR-15a and miR-16 affect the angiogenesis of multiple myeloma by targeting VEGF

(2012) Chun-Yan Sun et al.   CARCINOGENESIS

Evidence for serum miR-15a and miR-16 levels as biomarkers that distinguish sepsis from systemic inflammatory response syndrome in human subjects

(2012) Huijuan Wang et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Two new miR-16 targets: caprin-1 and HMGA1, proteins implicated in cell proliferation

(2009) Tagrid Kaddar et al.   BIOLOGY OF THE CELL

CCL20 produced in the cytokine network of rheumatoid arthritis recruits CCR6+ mononuclear cells and enhances the production of IL-6

(2009) Shimei Tanida et al.   CYTOKINE

miR-15b and miR-16 are implicated in activation of the rat hepatic stellate cell: An essential role for apoptosis

(2009) Can-Jie Guo et al.   JOURNAL OF HEPATOLOGY

Smad7 as a therapeutic agent for chronic kidney diseases

(2008) Hui Yao Lan   Frontiers in Bioscience-Landmark