Article
Obstetrics & Gynecology
R. K. Dhillon-Smith, P. Melo, A. J. Devall, P. P. Smith, M. Al-Memar, K. Barnhart, G. Condous, O. B. Christiansen, M. Goddijn, D. Jurkovic, D. Lissauer, A. Maheshwari, O. T. Oladapo, J. Preisler, L. Regan, R. Small, M. Stephenson, C. Wijeyaratne, S. Quenby, T. Bourne, A. Coomarasamy
Summary: The objective of this study was to develop core outcome sets (COS) for miscarriage management and prevention. Through a modified Delphi survey and consensus development meeting, stakeholders from 15 countries were included. The final COS for miscarriage management and prevention were established, providing important guidance for future randomized trials and systematic reviews.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Multidisciplinary Sciences
Elham Esfandiari, Anna M. Chudyk, Sanya Grover, Erica Y. Lau, Christiane Hoppmann, W. Ben Mortenson, Kate Mulligan, Christie Newton, Theresa Pauly, Beverley Pitman, Kathy L. Rush, Brodie M. Sakakibara, Bobbi Symes, Sian Tsuei, Robert J. Petrella, Maureen C. Ashe
Summary: This study protocol aims to co-create a core outcome set for middle-aged and older adults (40 years+) in social prescribing research, using modified Delphi methods. The study focuses on people involved in social prescribing and includes methods to evaluate collaboration. The three-part process includes identifying relevant systematic reviews, conducting online surveys, and convening a virtual team meeting to finalize the core outcome set.
Article
Multidisciplinary Sciences
Natalia dos Reis Ferreira, Carlos Miguel Machado Marto, Aleli Torres de Oliveira, Maria Joao Rodrigues, Marcos Fabio DosSantos
Summary: This study aims to develop a core outcome sets (COS) for clinical trials in intra-articular TMD and masticatory muscle disorders. By conducting systematic reviews and international Delphi surveys, the study aims to determine the core outcomes for TMD management interventions, reducing publication bias and enabling proper comparison of results.
Review
Allergy
Hywel C. Williams, Jochen Schmitt, Kim S. Thomas, Phyllis Spuls, Eric L. Simpson, Christian J. Apfelbacher, Joanne R. Chalmers, Masutaka Furue, Norito Katoh, Louise A. A. Gerbens, Yael A. Leshem, Laura Howells, Jasvinder A. Singh, Maarten Boers
Summary: Core outcome sets are crucial in atopic dermatitis research, providing a standardized approach to measuring outcomes and improving clinical practice.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2022)
Article
Health Care Sciences & Services
Ming Liu, Ya Gao, Yuan Yuan, Shuzhen Shi, Kelu Yang, Cuncun Lu, Jiarui Wu, Junhua Zhang, Jinhui Tian
Summary: This study revealed numerous inconsistencies between protocols and full-text publications in the development of core outcome sets (COSs), especially in terms of study types, databases searched, Delphi surveys, and face-to-face consensus meetings. Transparency regarding any changes to the methods is crucial in developing COSs.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2021)
Article
Medicine, General & Internal
Sarah A. Ibrahim, Bianca Y. Kang, Daniel Schlessinger, Sarah G. Chiren, Jennifer C. Tang, Jamie J. Kirkham, Jochen Schmitt, Emily Poon, Ian A. Maher, Joseph F. Sobanko, Todd Cartee, Murad Alam
Summary: This article describes a research plan on core outcomes in clinical trials of melasma. The study will extract potential outcomes through systematic literature reviews, patient interviews, and expert interviews, and will ultimately determine the core outcomes through a consensus meeting.
Article
Multidisciplinary Sciences
Hayat Hamzeh, Sally Spencer, Carol Kelly
Summary: This study aims to develop a core outcome set and outcome measurement set for physiotherapy research in adults with bronchiectasis, in order to ensure the consistent use and reporting of outcomes important to key stakeholders in future studies.
Article
Medicine, General & Internal
Jan R. Boehnke, Rusham Zahra Rana, Jamie J. Kirkham, Louise Rose, Gina Agarwal, Corrado Barbui, Alyssa Chase-Vilchez, Rachel Churchill, Oscar Flores-Flores, John R. Hurst, Naomi Levitt, Josefien van Olmen, Marianna Purgato, Kamran Siddiqi, Eleonora Uphoff, Rajesh Vedanthan, Judy Wright, Kath Wright, Gerardo A. Zavala, Najma Siddiqi
Summary: This article aims to develop core outcome sets (COSs) for interventions to prevent and treat multimorbidity in low-/middle-income countries (LMICs) through systematic reviews, Delphi surveys, and consensus meetings. The study has received approval for ethics and dissemination, and the findings will be disseminated through publications and conferences.
Review
Medicine, General & Internal
Tamer S. Sabet, David B. Anderson, Peter W. Stubbs, Rachelle Buchbinder, Caroline B. Terwee, Alessandro Chiarotto, Joel Gagnier, Arianne P. Verhagen
Summary: This study aims to identify common core domains from existing musculoskeletal core outcome sets (COSs) and facilitate the development of new COSs for musculoskeletal conditions. A systematic review will be conducted to describe the core domains recommended within each musculoskeletal COS, and common domains found may be used in the initial stages of development of future musculoskeletal COSs.
SYSTEMATIC REVIEWS
(2022)
Article
Medicine, General & Internal
Ting Zhang, Xuechao Li, Liang Zhao, Jiaoyan Zhang, Jinhui Tian, Junhua Zhang
Summary: This study aims to develop a core outcome set (COS) for clinical trials of traditional Chinese medicine (TCM)/Integrative Medicine in the treatment of stroke. The study includes systematic reviews and patient interviews to develop an initial outcome list, followed by Delphi surveys to prioritize important outcomes. The outcomes will be integrated into a core outcome set through a consensus meeting, aiming to improve the efficacy and safety outcomes of stroke treatment.
FRONTIERS IN MEDICINE
(2022)
Article
Dermatology
Anna Lechner, Susanne Coleman, Katrin Balzer, Jamie J. Kirkham, Delia Muir, Jane Nixon, Jan Kottner
Summary: Core outcomes for pressure ulcer prevention trials were identified through a workshop, a three-round Delphi survey, and an online consensus meeting. Six core outcomes were defined: pressure ulcer occurrence, pressure ulcer precursor signs and symptoms, mobility, acceptability and comfort of intervention, adherence/compliance, and adverse events/safety.
BRITISH JOURNAL OF DERMATOLOGY
(2022)
Article
Dermatology
T. Lange, J. Kottner, T. Weberschock, E. Hahnel, C. Apfelbacher, S. Brandstetter, A. Dreher, T. Datzmann, E. Burden-Teh, N. K. Rogers, P. Spuls, M. J. Grainge, L. Jacobi, H. C. Williams, J. Schmitt
Summary: Standardized outcome reporting is crucial for trial evidence synthesis and translation of findings into clinical decision-making. The OMERACT 2.0 Filter provides a framework for consistent reporting of outcomes, but there is currently a lack of a uniform dermatology-specific reporting strategy. Our study aimed to map efficacy/effectiveness outcomes assessed in dermatological trials to the OMERACT 2.0 Filter to develop a dermatology-specific outcome taxonomy, highlighting the need for precise and consistent outcome definitions in dermatology trials.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2021)
Article
Medicine, General & Internal
Xin Yue Dai, Ming Jie Zi, Chun Xiang Liu, Yi Ming Wang, Rui Gao
Summary: Diabetic foot is a common complication of diabetes, and traditional Chinese medicine treatment has certain advantages in addressing it. However, there is currently no core set of outcomes for measuring or monitoring diabetic foot with traditional Chinese medicine. Developing a core outcome set for traditional Chinese medicine in the treatment of diabetic foot is important for addressing these issues.
FRONTIERS IN MEDICINE
(2022)
Article
Health Care Sciences & Services
Karen Matvienko-Sikar, Kerry Avery, Jane M. Blazeby, Declan Devane, Susanna Dodd, Aoife M. Egan, Sarah L. Gorst, Karen Hughes, Pamela Jacobsen, Jamie J. Kirkham, Jan Kottner, Katie Mellor, Christopher P. Millward, Smitaa Patel, Fiona Quirke, Ian J. Saldanha, Valerie Smith, Caroline B. Terwee, Amber E. Young, Paula R. Williamson
Summary: This study examined current practices in late-phase trials published in major medical journals and investigated trialists' views on the use of core outcome sets (COS). The study found that the use of COS in these trials was low, even when relevant COS were available. The most common barrier to COS use was trialists' own outcome preferences and choice, while awareness and knowledge about COS were perceived as the most common facilitator.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2022)
Article
Medicine, Research & Experimental
Daphne H. H. Klerk, Otis C. C. van Varsseveld, Martin Offringa, Neena Modi, Martin Lacher, Augusto Zani, Mikko P. P. Pakarinen, Antti Koivusalo, Ingo Jester, Marie Spruce, Joep P. M. Derikx, Roel Bakx, Amine Ksia, Marijn J. J. Vermeulen, Elisabeth M. W. Kooi, Jan B. F. Hulscher
Summary: This study aims to develop a Core Outcome Set (COS) for the treatment trials of necrotizing enterocolitis (NEC) in preterm infants. Through systematic review and Delphi process, the research team will identify the most important outcomes and reach consensus with experts and patients worldwide. The final COS will contribute to the comparison and implementation of NEC treatment strategies.