Inhibition of Rho-kinase by Fasudil protects dopamine neurons and attenuates inflammatory response in an intranasal lipopolysaccharide-mediated Parkinson's model

Rho Kinase Inhibitor Fasudil Regulates Microglia Polarization and Function

(2017) Haifei Zhang et al.   NEUROIMMUNOMODULATION

Sex differences in Parkinson's disease and other movement disorders

(2014) Kara M. Smith et al.   EXPERIMENTAL NEUROLOGY

Macrophage Polarization in Bacterial Infections

(2014) M. Benoit et al.   JOURNAL OF IMMUNOLOGY

Inhibition of the microglial response is essential for the neuroprotective effects of Rho-kinase inhibitors on MPTP-induced dopaminergic cell death

(2014) Ana Borrajo et al.   NEUROPHARMACOLOGY

Rho Kinase Inhibitor Fasudil Protects againstβ-Amyloid-Induced Hippocampal Neurodegeneration in Rats

(2013) Yun Song et al.   CNS Neuroscience & Therapeutics

Alpha-synuclein promotes early neurite outgrowth in cultured primary neurons

(2013) Guangwei Liu et al.   JOURNAL OF NEURAL TRANSMISSION

Activation of microglia induces symptoms of Parkinson’s disease in wild-type, but not in IL-1 knockout mice

(2013) Sachiko Tanaka et al.   Journal of Neuroinflammation

Inhibition of Rho kinase mediates the neuroprotective effects of estrogen in the MPTP model of Parkinson's disease

(2013) Ana I. Rodriguez-Perez et al.   NEUROBIOLOGY OF DISEASE

Innate Immune Response of Alveolar Macrophage to House Dust Mite Allergen Is Mediated through TLR2/-4 Co-Activation

(2013) Chia-Fang Liu et al.   PLoS One

Critical Role of Regulator G-Protein Signaling 10 (RGS10) in Modulating Macrophage M1/M2 Activation

(2013) Jae-Kyung Lee et al.   PLoS One

Intranasal LPS-Mediated Parkinson’s Model Challenges the Pathogenesis of Nasal Cavity and Environmental Toxins

(2013) Qing He et al.   PLoS One

Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease

(2012) L. Tonges et al.   BRAIN

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Involvement of microglial RhoA/Rho-Kinase pathway activation in the dopaminergic neuron death. Role of angiotensin via angiotensin type 1 receptors

(2012) Begoña Villar-Cheda et al.   NEUROBIOLOGY OF DISEASE

Fasudil and Ozagrel in Combination Show Neuroprotective Effects on Cerebral Infarction after Murine Middle Cerebral Artery Occlusion

(2011) A. Koumura et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

A randomized pilot trial of estrogen replacement therapy in post-menopausal women with Parkinson’s disease

(2011)   PARKINSONISM & RELATED DISORDERS

Macrophage Polarization in Health and Disease

(2011) Luca Cassetta et al.   TheScientificWorldJOURNAL

Hydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer's disease by reduction of oxidative stress

(2010) Jian Li et al.   BRAIN RESEARCH

Mechanisms Underlying Inflammation in Neurodegeneration

(2010) Christopher K. Glass et al.   CELL

Fasudil protects hippocampal neurons against hypoxia-reoxygenation injury by suppressing microglial inflammatory responses in mice

(2010) Jing Ding et al.   JOURNAL OF NEUROCHEMISTRY

Parkinson's Disease

(2009) Christopher H. Hawkes et al.   Annals of the New York Academy of Sciences

Rho Kinase (ROCK) Inhibitors and Their Application to Inflammatory Disorders

(2009) Philip LoGrasso et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Purification, Cloning, and Functional Characterization of a Novel Immunomodulatory Protein from Antrodia camphorata (Bitter Mushroom) That Exhibits TLR2-Dependent NF-κB Activation and M1 Polarization within Murine Macrophages

(2009) Fuu Sheu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Highly pathogenic H5N1 influenza virus can enter the central nervous system and induce neuroinflammation and neurodegeneration

(2009) H. Jang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NF-κB and phosphatidylinositol 3-kinase activity mediates the HCMV-induced atypical M1/M2 polarization of monocytes

(2009) Gary Chan et al.   VIRUS RESEARCH

The olfactory vector hypothesis of neurodegenerative disease: Is it viable?

(2008) Richard L. Doty   ANNALS OF NEUROLOGY

Nuclear Factor-κB Activation: From Bench to Bedside

(2008) Gautam Sethi et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

The lipopolysaccharide Parkinson’s disease animal model: mechanistic studies and drug discovery

(2008) Garima Dutta et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Nitrated Alpha-Synuclein and Microglial Neuroregulatory Activities

(2008) Ashley D. Reynolds et al.   Journal of Neuroimmune Pharmacology